Reference of 36404-90-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 36404-90-7, name is 2-Fluoro-3-formylpyridine, molecular formula is C6H4FNO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Add 50g of intermediate 1-1 to a 1L three-necked flask.19.0 g of intermediate 6-1,29.3g potassium carbonate,30g 4A molecular sieve,500ml acetonitrile,The temperature was raised to 80 C and the reaction was stirred for 10 h.TLC monitors the raw materials to complete room temperature and then drops to room temperature.The reaction mixture was concentrated by filtration. The obtained crude crystals were evaporated to dryness.
According to the analysis of related databases, 36404-90-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Xi’an Ruilian New Materials Co., Ltd.; Sun Jun; Liu Kaipeng; Zhang Hongke; Guo Jing; Wang Xiaowei; Liu Qianfeng; Gao Renxiao; (35 pag.)CN109293583; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem