Month: November 2021

Product Details of 91-02-1. Bravo, C; Robalo, MP; Marques, F; Fernandes, AR; Sequeira, DA; Piedade, MFM; Garcia, MH; de Brito, MJV; Morais, TS in [Bravo, Catarina; Sequeira, Diogo A.; Helena Garcia, M.; Villa de Brito, Maria J.; Morais, Tania S.] Univ Lisbon, Fac Ciencias, Ctr Quim Estrutural, Lisbon, Portugal; [Bravo, Catarina; Piedade, M. Fatima M.; Helena Garcia, M.; Villa de Brito, Maria J.; Morais, Tania S.] Univ Lisbon, Fac Ciencias, Dept Quim & Bioquim, Lisbon, Portugal; [Paula Robalo, M.; Piedade, M. Fatima M.] Univ Lisbon, Inst Super Tecn, Ctr Quim Estrutural, Lisbon, Portugal; [Paula Robalo, M.] Inst Politecn Lisboa, Inst Super Engn Lisboa, Area Dept Engn Quim, Rua Conselheiro Emidio Navarro 1, P-1959007 Lisbon, Portugal; [Marques, Fernanda] Univ Lisbon, Inst Super Tecn, Dept Engn & Ciencias Nucl, Ctr Ciencias & Tecnol Nucl, Lisbon, Portugal; [Fernandes, Alexandra R.; Sequeira, Diogo A.] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Ciencias Vida, UCBIO, Lisbon, Portugal published First heterobimetallic Cu(i)-dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity in 2019.0, Cited 50.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

A new family of eight heterobimetallic Cu(i)-dppf complexes of general formula [Cu(dppf)L][BF4] with dppf = 1,1 ‘-bis(diphenylphosphino)ferrocene and L representing N,N-, N,O- and N,S-heteroaromatic bidentate ligands have been synthesized and fully characterized by classical analytical, spectroscopic and electrochemical methods. The single crystal structures of [Cu(dppf)(pBI)][BF4] (6), [Cu(dppf)(dpytz)][BF4] (7) and [Cu(dppf)(5-Aphen)][BF4] (8) complexes (where pBI = 2-(2-pyridyl)benzimidazole, dpytz = 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine and 5-Aphen = 1,10-phenanthrolin-5-amine) were determined by X-ray diffraction studies. Cytotoxicity of all complexes was evaluated in two human breast adenocarcinoma cell lines (MCF7 and MDAMB231). All the complexes exhibit high cytotoxicity against both human breast cancer cells with IC50 values far lower than those found for the antitumor drug cisplatin in the same cell lines. The IC50 values on primary healthy fibroblasts are of the same order of magnitude as those found for the tumoral cells.

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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about FLUORIDE-ION; ANION; FLUORESCENCE; AGGREGATION; METALLOGELS; DYE; CHEMOSENSORS; RECOGNITION; VITAMIN-B-6; DERIVATIVES, Saw an article supported by the UGC, New Delhi, IndiaUniversity Grants Commission, India; SERB, DST, New Delhi [EMR/2016/008005/OC]. Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Pati, C; Ghosh, K. The CAS is 65-22-5. Through research, I have a further understanding and discovery of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

A naphthalimide-pyridoxal conjugate 1 has been designed and synthesized. Compound 1 forms a stable greenish yellow colored gel in DMSO:H2O (8:1 v/v). Rheological study reveals that the gel is mechanically strong (G> G) over a wide range of applied strains. The morphology of the gel as determined by FESEM shows a highly cross-linked fibrous network. The gel is anion-responsive and is selectively transformed into a sol with a color change from greenish yellow to deep blue only in the presence of F- among other anions. In CH3CN, compound 1 was also sensitive to basic anions such as F- and AcO- ions. In solution, F- was differentiated from AcO- through a color change. While the yellow colored solution of 1 in acetonitrile was changed into deep blue in the presence of F-, AcO- ions gave a faint blue coloration. A similar colorimetric differentiation of F- from AcO- has been possible in CH3CN by a reusable Schiff base-linked Merrifield resin 1a or 1b.

Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Bye, fridends, I hope you can learn more about C8H10ClNO3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 91-02-1. In 2020.0 CHEM COMMUN published article about FUNCTIONALIZATION; ARENES; DECARBONYLATION; SULFONATION; ACTIVATION; AMIDATION; MILD in [Li, Gang; Cai, Xiaofeng; Zhong, Lei; Zou, Lei] Anyang Normal Univ, Coll Chem & Chem Engn, Anyang 455000, Peoples R China; [Li, Gang; Cai, Xiaofeng; Zhong, Lei; Zou, Lei] Anyang Normal Univ, Henan Prov Key Lab New Optoelect Funct Mat, Anyang 455002, Peoples R China; [Jia, Chunqi; Cui, Xiuling] Huaqiao Univ, Key Lab Fujian Mol Med, Key Lab Xiamen Marine & Gene Drugs, Sch Biomed Sci,Engn Res Ctr Mol Med,Minist Educ, Xiamen 361021, Fujian, Peoples R China in 2020.0, Cited 41.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

The first example of meta-selective C-Ar-H bond functionalization of aryl 2-pyridyl ketones has been developed using [Ru(p-cymene)Cl-2](2) as the catalyst and alkyl bromide as the coupling reagent. This development provides an efficient strategy for modifying the meta-position of aryl 2-pyridyl ketone skeletons, which are found in various functional molecules.

Product Details of 91-02-1. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Name: 3-Pyridinecarboxaldehyde. Recently I am researching about ALZHEIMERS-DISEASE; GSK-3 INHIBITORS; DESIGN; CANCER; GENE; COMBINATION; INDIRUBINS; METABOLISM; SIMULATION; EFFICIENT, Saw an article supported by the Russian Foundation for Basic Research (RFBR), RussiaRussian Foundation for Basic Research (RFBR) [17-03-01320]; Council on grants of the President of the Russian Federation [SP-595.2018.4]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Lozinskaya, NA; Babkov, DA; Zaryanova, EV; Bezsonova, EN; Borisov, AV; Tsymlyakov, MD; Anikina, LV; Zakharyascheva, OY; Borisov, AV; Perfilova, VN; Tyurenkov, IN; Proskurnina, MV; Spasov, AA. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde

Glycogen synthase kinase 3 beta (GSK-3 beta) is a widely investigated molecular target for numerous diseases including Alzheimer’s disease, cancer, and diabetes mellitus. Inhibition of GSK-3 beta activity has become an attractive approach for treatment of diabetes and cancer. We report the discovery of novel GSK-3 beta inhibitors of 3-arylidene-2-oxindole scaffold with promising activity. The most potent compound 3a inhibits GSK-3 beta with IC(50 )4.19 nM. In a cell-based assay 3a shows no significant leucocyte toxicity at 10 mu M and is moderately cytotoxic against A549 cells. Compound 3a demonstrated high antidiabetic efficacy in obese streptozotocin-treated rats improving glucose tolerance at a dose of 50 mg/kg body weight thus representing an interesting lead for further optimization.

Name: 3-Pyridinecarboxaldehyde. Welcome to talk about 500-22-1, If you have any questions, you can contact Lozinskaya, NA; Babkov, DA; Zaryanova, EV; Bezsonova, EN; Borisov, AV; Tsymlyakov, MD; Anikina, LV; Zakharyascheva, OY; Borisov, AV; Perfilova, VN; Tyurenkov, IN; Proskurnina, MV; Spasov, AA or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Synthesis and Characterization of Magnetic Functionalized Ni and Cu Nano Catalysts and Their Application in Oxidation, Oxidative Coupling and Various Multi-Component Reactions WOS:000604191500004 published article about ONE-POT SYNTHESIS; RECYCLABLE CATALYST; EFFICIENT CATALYST; 5-SUBSTITUTED 1H-TETRAZOLES; SELECTIVE OXIDATION; HYDROGEN-PEROXIDE; IRON-OXIDE; NANOPARTICLES; SULFIDES; COMPLEX in [Hajjami, Maryam] Bu Ali Sina Univ, Dept Organ Chem, Fac Chem, Hamadan 6517838683, Hamadan, Iran; [Sheikhaei, Shiva; Gholamian, Fatemeh; Yousofvand, Zakieh] Ilam Univ, Fac Sci, Dept Chem, POB 69315516, Ilam, Iran in 2021.0, Cited 47.0. Safety of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Two magnetic nano catalysts of nickel and copper, Fe3O4@SiO2@DOP-BenPyr-M(II), (M=Ni and Cu) have been synthesized. These catalysts were applied as recoverable, efficient and new heterogeneous catalysts for the high yielding and room temperature one-pot procedure of selective oxidation of sulfides to sulfoxides and oxidative coupling of thiols to disulfides. In addition, the catalytic activity of Fe3O4@SiO2@DOP-BenPyr-Ni(II) was investigated as heterogeneous nanocatalyst for synthesis of 2,3-dihydroquinazolin-4(1H)-ones, 5-substituted 1H-tetrazoles and polyhydroquinolines. The synthesized catalysts were characterized by FT-IR, TGA, XRD, VSM, EDX, ICP and SEM techniques. These catalysts were recovered by an external magnet and reused several times without significant loss of catalytic efficiency. [GRAPHICS] .

Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.. Safety of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Chatterjee, A; Khan, S; Ghosh, R in PERGAMON-ELSEVIER SCIENCE LTD published article about COBALT(III) COMPLEX; CATECHOLASE; OXIDATION; DIOXYGEN; LIGAND; EXAMPLE in [Chatterjee, Arnab; Ghosh, Rajarshi] Univ Burdwan, Dept Chem, Burdwan 713104, W Bengal, India; [Khan, Sumitava] Burdwan Raj Coll, Dept Chem, Burdwan 713104, W Bengal, India in 2019.0, Cited 32.0. HPLC of Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Three new mononuclear complexes of the type [M(L)(2)](ClO4)(2), with Ni(II) (1), Cu(II) (2) and Zn(II) (3) ions, have been synthesized and structurally characterized, using the N,N,O donor Schiff base ligand 2-[(phenyl-pyridine-2-yl-methylene)-amino]-ethanol]. An X-ray diffraction study reveals identical crystallization patterns for each of the complexes, in the monoclinic crystal system with the C2/c space group. Interestingly, the synthesized complexes are isostructural in nature. The complexes showed biomimetic phenoxazinone synthase-like activity for the aerial oxidation of o-aminophenol to phenoxazine-2-one, separately in methanol (MeOH) and acetonitrile (ACN) solutions. For each of the complexes, the turnover numbers were found to be higher in MeOH than in ACN. The highest catalytic activity between among the three complexes was found to be for complex 2. (C) 2019 Elsevier Ltd. All rights reserved.

Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Recently I am researching about EPITHELIAL OVARIAN CARCINOMAS; NITRIC-OXIDE SYNTHASE; HYDROXY-L-ARGININE; PROGNOSTIC VALUE; CANCER; EXPRESSION; RECEPTOR; MICROENVIRONMENT; THERAPIES; SURVIVAL, Saw an article supported by the University of New England office of research and scholarship; University of New England college of Pharmacy. Published in ELSEVIER URBAN & PARTNER SP Z O O in WROCLAW ,Authors: Mohan, S; Patel, S; Barlow, D; Rojas, AC. The CAS is 65-22-5. Through research, I have a further understanding and discovery of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Purpose: We investigated Nw-hydroxy L-Arginine (NOHA) predictive response in serous ovarian carcinoma based on estrogen-hormone receptor expression status; and assessed the distinctive NOHA response between estrogen-receptor-negative (ER-) tumor subtypes of ovarian and breast cancer. Materials/methods: Three-dimensional (3D) spheroids models of ER- and estrogen-receptor-positive (ER+) from breast and ovarian tumor, cultured for 9 weeks, were assayed for cellular levels of inducible nitric oxide synthase (NOS2), nitric oxide (as total nitrite) and L-Arginine, and compared to NOHA in culture medium. Statistical difference was set at p < 0.01. Results: Nine-week in vitro studies showed a progressive NOHA reduction in culture medium by at least 0.4-0.8 fold, and 0.65-0.92 fold only in the ER-breast tumor and ER-ovarian tumor 3D spheroids, respectively; with increases in cellular NOS2 and nitric-oxide levels, by at least 1.0-2.45 fold in both ER-tumor subtype 3D spheroids (p < 0.01; n = 6). Within ER-subtypes, medium NOHA decreased by >= 38.9% in ovarian cancer over breast cancer 3D-spheroids, with cellular increases in NOS2 (by >= 17.4%), and nitric oxide (by >= 18.8%). Cellular L-Arginine to medium NOHA ratio was higher, and by at least 6.5-22.5 fold in ER-breast tumor 3D-spheroids, and at least 10-70 fold in ER-ovarian tumor 3D spheroids, than in ER+ and control conditions; and was >= 48% higher in ER-ovarian cancer than in ER-breast cancer 3D-spheroids. Conclusions: The present study shows NOHA as a sensitive and selective indicator differentiating and distinguishing ER-subtypes based on the tumor grade.

Welcome to talk about 65-22-5, If you have any questions, you can contact Mohan, S; Patel, S; Barlow, D; Rojas, AC or send Email.. Safety of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Structurally characterized mononuclear isostructural Ni(II), Cu(II) and Zn (II) complexes as a functional model for phenoxazinone synthase activity WOS:000499768700046 published article about COBALT(III) COMPLEX; CATECHOLASE; OXIDATION; DIOXYGEN; LIGAND; EXAMPLE in [Chatterjee, Arnab; Ghosh, Rajarshi] Univ Burdwan, Dept Chem, Burdwan 713104, W Bengal, India; [Khan, Sumitava] Burdwan Raj Coll, Dept Chem, Burdwan 713104, W Bengal, India in 2019.0, Cited 32.0. COA of Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Three new mononuclear complexes of the type [M(L)(2)](ClO4)(2), with Ni(II) (1), Cu(II) (2) and Zn(II) (3) ions, have been synthesized and structurally characterized, using the N,N,O donor Schiff base ligand 2-[(phenyl-pyridine-2-yl-methylene)-amino]-ethanol]. An X-ray diffraction study reveals identical crystallization patterns for each of the complexes, in the monoclinic crystal system with the C2/c space group. Interestingly, the synthesized complexes are isostructural in nature. The complexes showed biomimetic phenoxazinone synthase-like activity for the aerial oxidation of o-aminophenol to phenoxazine-2-one, separately in methanol (MeOH) and acetonitrile (ACN) solutions. For each of the complexes, the turnover numbers were found to be higher in MeOH than in ACN. The highest catalytic activity between among the three complexes was found to be for complex 2. (C) 2019 Elsevier Ltd. All rights reserved.

Welcome to talk about 91-02-1, If you have any questions, you can contact Chatterjee, A; Khan, S; Ghosh, R or send Email.. COA of Formula: C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Huang, C; Qiao, J; Ci, RN; Wang, XZ; Wang, Y; Wang, JH; Chen, B; Tung, CH; Wu, LZ in CELL PRESS published article about SP(3) C-H; LIGHT PHOTOREDOX CATALYSIS; TRANSITION-METAL; FUNCTIONALIZATION; ALLYLATION; CARBONYL; PHOTOCATALYSIS; SELECTIVITY; ACTIVATION; ALDEHYDES in [Huang, Cheng; Qiao, Jia; Ci, Rui-Nan; Wang, Xu-Zhe; Wang, Yang; Wang, Jing-Hao; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China; [Huang, Cheng; Qiao, Jia; Ci, Rui-Nan; Wang, Xu-Zhe; Wang, Yang; Wang, Jing-Hao; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu] Chinese Acad Sci, Univ Chinese Acad Sci, Beijing 100190, Peoples R China; [Huang, Cheng; Qiao, Jia; Ci, Rui-Nan; Wang, Xu-Zhe; Wang, Yang; Wang, Jing-Hao; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu] Univ Chinese Acad Sci, Sch Future Technol, Beijing 100049, Peoples R China in 2021, Cited 67. COA of Formula: C8H9NO2. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6

Direct alkylation and arylation of allylic C(sp3)-H bonds are straight-forward approaches for accessing allylic C-C products. However, the engagement of allylic C-C bond- forming reaction without introducing extraneous functional groups and stoichiometric oxidant or reductant has proved difficult. Here, we report a general and mild strategy using semiconductor quantum dots (QDs) as photocatalysts for coupling a broad range of available allylic C(sp(3))-H bonds with alpha- amino C-H bonds or heteroarenes, respectively, under sunlight irradiation (> 85 examples). The protocol bypasses stoichiometric oxidant or reductant and pre-functionalization of both the coupling partners and produces hydrogen (H-2) as the byproduct. The outstanding efficiency and selectivity and step- and atom-economy represents the first direct alkylation and arylation of allylic C(sp(3))-H bonds with hydrogen evolution powered by solar energy.

Welcome to talk about 614-18-6, If you have any questions, you can contact Huang, C; Qiao, J; Ci, RN; Wang, XZ; Wang, Y; Wang, JH; Chen, B; Tung, CH; Wu, LZ or send Email.. COA of Formula: C8H9NO2

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Structural divergence in binuclear Cu(ii) pyridoxal Schiff base complexes probed by co-ligands: catecholase mimetic activity and sulphide ion sensing WOS:000554833200003 published article about 2,6-DIACETYLPYRIDINE DAP HYDRAZONES; CRYSTAL-STRUCTURES; SPECTROSCOPIC PROPERTIES; MAGNETIC-PROPERTIES; AROYL HYDRAZONES; II COMPLEXES; COPPER(II); OXIDASE; COORDINATION; MN(II) in [Chakraborty, Moumita; Mondal, Antu; Chattopadhyay, Shyamal Kumar] Indian Inst Engn Sci & Technol, Dept Chem, Sibpur 711103, Howrah, India in 2020.0, Cited 74.0. COA of Formula: C8H10ClNO3. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5

Three hydroxymethyl bridged Cu(ii) complexes of a pyridoxal Schiff base ligand 4-((E)-(2-(pyridin-2-yl)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (LH) have been synthesized and characterized on the basis of spectroscopic, elctrochemical and structural properties. The X-ray crystal structures of the complexes reveal dual denticity of the ligand, bidenticity in the absence of a co-ligand as in complex1, and tridenticity in the presence of a co-ligand such as SCN-/N(CN)(2)(-)as in complexes2and3. The complexes, though binuclear in the solid state, exist as a monomeric unit in solution due to the exceptionally long axial Cu-O-hydroxymethyl(2.4-2.5 angstrom) bond. All three complexes show efficient catalytic activities towards the aerial oxidation of 3,5-ditertiarybutylcatechol (DTBCH2) withk(cat)values of 5.38 x 10(4)h(-1), 1.18 x 10(5)h(-1)and 1.06 x 10(5)h(-1)in methanol. Complexes1and2also act as a selective sulphide ion sensor withK(b)values of 6.6 x 10(3)M(-1)and 8.1 x 10(3)M(-1), respectively, while their respective L.O.D. values are 3.4 mu M and 3.2 mu M.

COA of Formula: C8H10ClNO3. Welcome to talk about 65-22-5, If you have any questions, you can contact Chakraborty, M; Mondal, A; Chattopadhyay, SK or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem