Month: January 2022

Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. In 2019.0 NEW J CHEM published article about COORDINATION CHEMISTRY; FLUORESCENT SENSORS; CU(II) COMPLEXES; SYNAPTIC ZINC; MECHANISM; RUTHENIUM(II); VITAMIN-B-6; COPPER(II); INDUCTION; LIGANDS in [Mondal, Satyajit; Chakraborty, Moumita; Mondal, Antu; Pakhira, Bholanath; Chattopadhyay, Shyamal Kumar] Indian Inst Engn Sci & Technol, Dept Chem, Sibpur 711103, Howrah, India; [Mukhopadhyay, Subhra Kanti; Banik, Avishek] Univ Burdwan, Dept Microbiol, Burdwan 713104, W Bengal, India; [Sengupta, Swaraj] Birla Inst Technol, Dept Chem, Ranchi 835215, Jharkhand, India in 2019.0, Cited 67.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5.

Herein we report, a mononuclear, highly fluorescent zinc(ii) complex Zn(L)(N-3)(H2O) (1) that was prepared by an easy one pot method, in which the tridentate Schiff base ligand (E)-4-((2-(dimethylamino)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (HL) was generated in situ. The compound is characterized by various spectroscopic techniques, and its structure was determined by single crystal X-ray diffraction studies. DFT calculations were used to understand the electronic structures of the ligand and the complex, and TD-DFT calculations were performed to interpret the nature of the electronic transitions observed in their UV-vis spectra. In the complex, Zn(II) is found to be penta-coordinated with one azide ligand, an aqua ligand and a monoanionic tridentate N,N,O-donor ligand. In an aqueous methanol (1:9 by volume) solution, at the physiological pH (0.01 M Tris-HCl buffer, pH 7.4), compound 1 exhibits an intense greenish blue fluorescence (lambda(ex) 390 nm, lambda(em) 462 nm), whose intensity is about 17-fold stronger than that of the free ligand. Compound 1 is found to show significant DNA binding activity. The pyridoxal appended tridentate ligand can be used for the bio-imaging of Zn(II).

Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. About 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride, If you have any questions, you can contact Mondal, S; Chakraborty, M; Mondal, A; Pakhira, B; Mukhopadhyay, SK; Banik, A; Sengupta, S; Chattopadhyay, SK or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: 65-22-5. I found the field of Chemistry very interesting. Saw the article A novel diarylethene probe with high selective recognition of CN- and Mg2+ and its application published in 2020.0, Reprint Addresses Li, H; Pu, SZ (corresponding author), Jiangxi Sci & Technol Normal Univ, Jiangxi Key Lab Organ Chem, Nanchang 330013, Jiangxi, Peoples R China.. The CAS is 65-22-5. Through research, I have a further understanding and discovery of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride.

A chemical sensor composed of pyridoxal hydrochloride schiff base based on diarylethene (1O) was synthesized. Its photochemical properties and selectivity to ions were further studied. The chemosensor could detect cyanide effectively and is almost undisturbed by other ions. When titrating CN-, the reaction aroused a distinct change in the absorption spectrum with the color change from transparent to yellow, and the fluorescence intensity centered at 562 nm was increased 68 folds. It also exhibited a good fluorescence sensing of Mg(2+ )with high selectivity and sensitivity. Upon addition of Mg2+, its emission intensity enhanced 110 folds, with the color change from dark to bright blue. Its good spectral response could be applied to molecular logic circuit. Moreover, the chemosensor could be made into test paper strips for the qualitative and quantitative detection of CN- and Mg2+.

Welcome to talk about 65-22-5, If you have any questions, you can contact Yuwen, ZY; Mei, HX; Li, H; Pu, SZ or send Email.. Recommanded Product: 65-22-5

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Molecular structures, spectral, electrochemical, DFT and antioxidant activities of copper(II) complexes with NNO donor Schiff base ligand WOS:000609160500005 published article about TRANSITION-METAL-COMPLEXES; X-RAY STRUCTURES; CRYSTAL-STRUCTURE; ELECTRONIC-PROPERTIES; SUPEROXIDE; BINUCLEAR; NITROGEN; MIMICS; ION; STEREOCHEMISTRY in [Singh, Yogendra Pratap; Patel, Satish Kumar] APS Univ, Dept Chem, Rewa 486003, MP, India in 2021.0, Cited 72.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Product Details of 91-02-1

The synthesis and solid state structural, spectral and electrochemical solution characterization of [Cu(L)(acpy)]ClO4 1 and [Cu(L)(NO3)]( )2 [where L = N'[(E)-phenyl(pyridin-2-yl)methylideneithiophene-2-carbohydrazide and acpy = 2,6-Diacetylpyridine] have been done by elemental analysis, UV-vis, FTIR, electrochemical techniques (CV and DPV) and electron paramagnetic resonance (epr) spectroscopy. The single crystal structures were solved by the X-ray diffraction technique. In complex 1, copper ion is in a distorted octahedral environment. The geometry of copper(II) in complex 2 is distorted square pyramidal (tau = 0.201). The mono deprotonated, HL ligand act as a tridentate to a copper(II) ion. On the basis of density functional theory (DFT) calculation, the electronic excitations involve transitions mainly from metal ligand bonding mostly the alpha-LUMO within the dominant Cu d(xy) character and to alpha-LUMO+1. Epr spectra for polycrystalline samples showed the copper(II) hyperfine features as well as half-field signal which are appropriate for Delta M-s = +/- 2 of dimers. Presence of half-field signal in 1 is due to solid-solid interaction (intra-molecular) where as in 2 the nature of interaction is intra-molecular. The antioxidant superoxide measurements show that the both complexes 1 and 2 behave as superoxide mimic in alkaline nitro blue tetrazolium chloride assay. (C) 2020 Elsevier B.V. All rights reserved.

Product Details of 91-02-1. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Microwave-assisted synthesis and antibacterial propensity of N ‘-s-benzylidene-2-propylquinoline-4-carbohydrazide and N ‘-((s-1H-pyrrol-2-yl)methylene)-2-propylquinoline-4-carbohydrazide motifs WOS:000505076000135 published article about QUINOLINE DERIVATIVES; ESCHERICHIA-COLI; BINDING; MECHANISMS; RESISTANCE; DOCKING; OVENS in [Ajani, Olayinka O.; Iyaye, King T.; Aderohunmu, Damilola V.; Olanrewaju, Ifedolapo O.] Covenant Univ, Dept Chem, CST, Km 10 Idiroko Rd,PMB 1023, Ota, Ogun State, Nigeria; [Germann, Markus W.; Bello, Babatunde L.] Georgia State Univ, Dept Chem, Atlanta, GA 30302 USA; [Olorunshola, Shade J.] Covenant Univ, Dept Biol Sci, CST, Km 10 Idiroko Rd,PMB 1023, Ota, Ogun State, Nigeria in 2020.0, Cited 53.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1. COA of Formula: C6H5NO

Microwave-assisted approach was utilized as green approach to access a series of 2-pro pylquinoline-4-carbohydrazide hydrazone derivatives 10a-j of aromatic and heteroaromatic aldehydes in highly encouraging yields. It involved four steps reaction which was initiated with ring opening reaction of isatin in a basified environment and subsequent cross-coupling with pentan-2-one to produce compound 7. Esterification of 7 in acid medium led to the formation of compound 8 which was reacted with hydrazine hydrate to access 9 which upon microwave-assisted condensed with aromatic and heteroaromatic aldehydes furnished the targeted compounds 10a-j. The structures of 10aj were confirmed by physico-chemical, elemental analyses and spectroscopic characterization which include UV, FT-IR, H-1 and C-13 NMR as well as DEPT-135. The targeted compounds 10a-j, alongside with gentamicin clinical standard, were investigated for their antibacterial efficacies using agar diffusion method. 2-Propyl-N’-(pyridine-3-ylmethylene) quinoline-4-carbohydrazide 10j emerged as the best antibacterial hydrazide-hydrazone with lowest MIC value of 0.39 +/- 0.02 – 1.56 +/- 0.02 mu g/ mL across all the organisms screened. (C) 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University.

COA of Formula: C6H5NO. Welcome to talk about 500-22-1, If you have any questions, you can contact Ajani, OO; Iyaye, KT; Aderohunmu, DV; Olanrewaju, IO; Germann, MW; Olorunshola, SJ; Bello, BL or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 65-22-5. In 2019.0 NEW J CHEM published article about COORDINATION CHEMISTRY; FLUORESCENT SENSORS; CU(II) COMPLEXES; SYNAPTIC ZINC; MECHANISM; RUTHENIUM(II); VITAMIN-B-6; COPPER(II); INDUCTION; LIGANDS in [Mondal, Satyajit; Chakraborty, Moumita; Mondal, Antu; Pakhira, Bholanath; Chattopadhyay, Shyamal Kumar] Indian Inst Engn Sci & Technol, Dept Chem, Sibpur 711103, Howrah, India; [Mukhopadhyay, Subhra Kanti; Banik, Avishek] Univ Burdwan, Dept Microbiol, Burdwan 713104, W Bengal, India; [Sengupta, Swaraj] Birla Inst Technol, Dept Chem, Ranchi 835215, Jharkhand, India in 2019.0, Cited 67.0. The Name is 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. Through research, I have a further understanding and discovery of 65-22-5.

Herein we report, a mononuclear, highly fluorescent zinc(ii) complex Zn(L)(N-3)(H2O) (1) that was prepared by an easy one pot method, in which the tridentate Schiff base ligand (E)-4-((2-(dimethylamino)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (HL) was generated in situ. The compound is characterized by various spectroscopic techniques, and its structure was determined by single crystal X-ray diffraction studies. DFT calculations were used to understand the electronic structures of the ligand and the complex, and TD-DFT calculations were performed to interpret the nature of the electronic transitions observed in their UV-vis spectra. In the complex, Zn(II) is found to be penta-coordinated with one azide ligand, an aqua ligand and a monoanionic tridentate N,N,O-donor ligand. In an aqueous methanol (1:9 by volume) solution, at the physiological pH (0.01 M Tris-HCl buffer, pH 7.4), compound 1 exhibits an intense greenish blue fluorescence (lambda(ex) 390 nm, lambda(em) 462 nm), whose intensity is about 17-fold stronger than that of the free ligand. Compound 1 is found to show significant DNA binding activity. The pyridoxal appended tridentate ligand can be used for the bio-imaging of Zn(II).

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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Name: Phenyl(pyridin-2-yl)methanone. Recently I am researching about ASYMMETRIC HYDROGENATION; NITRIC-ACID; CHEMISTRY; SYSTEM; GENERATION; CONVERSION; NITRATION; ARYL, Saw an article supported by the Shanghai Post-doctoral Excellence Program, Shanghai Sailing Program [20YF1410400]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21572056]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities; 111 projectMinistry of Education, China – 111 Project [B07023]; Open Project of State Key Laboratory of Chemical Engineering [SKL-ChE-17C01]. Published in SPRINGER in NEW YORK ,Authors: Sun, ML; Li, JC; Liang, CM; Shan, C; Shen, XY; Cheng, RH; Ma, YY; Ye, JX. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

2-Pyridyl ketones widely appear in bioactive molecules, natural products, and are employed as precursors of chiral 2-pyridine alky/aryl alcohols or 2-aminoalkyl pyridine ligands for asymmetric catalysis. Herein, a practical method for the rapid synthesis of 2-pyridyl ketone library in continuous flow is reported, in which the 2-lithiopyridine formed by Br/Li exchange reacts with commercially available esters to obtain 2-pyridyl ketones in a good yield at short reaction time. This protocol functions broadly on a variety of esters and has been applied to the synthesis of TGF-beta type 1 receptor inhibitor LY580276 intermediate in an environmentally friendly method. It is rapid, reliable, and cost-efficient to afford diverse kinds of 2-pyridyl ketones in the compound library.

Name: Phenyl(pyridin-2-yl)methanone. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Polynuclear zinc(II) complexes of thiosemicarbazone: Synthesis, X-ray structure and biological evaluation WOS:000510109900013 published article about RUTHENIUM(II) ARENE COMPLEXES; VITRO ANTICANCER ACTIVITY; IN-VITRO; RIBONUCLEOTIDE REDUCTASE; ZN(II) COMPLEXES; DNA CLEAVAGE; PHASE-II; 3-AMINOPYRIDINE-2-CARBOXALDEHYDE THIOSEMICARBAZONE; SPECTRAL CHARACTERIZATION; CYTOTOXIC ACTIVITIES in [Saswati; Mohanty, Monalisa; Banerjee, Atanu; Biswal, Sonaleen; Dinda, Rupam] Natl Inst Technol, Dept Chem, Rourkela 769008, Odisha, India; [Horn, Adolfo, Jr.] Univ Estadual Norte Fluminense, Lab Ciencias Quim, Campos Dos Goytacaces, RJ, Brazil; [Schenk, Gerhard] Univ Queensland, Sch Chem & Mol Biosci, St Lucia, Qld 4072, Australia; [Brzezinski, Krzysztof] Univ Bialystok, Inst Chem, Ciolkowskiego 1K, PL-15245 Bialystok, Poland; [Sinn, Ekkehard] Western Michigan Univ, Dept Chem, Kalamazoo, MI 49008 USA; [Reuter, Hans] Univ Osnabruck, Inst Chem New Mat, Barbarastr 6, D-49069 Osnabrucks, Germany in 2020.0, Cited 98.0. Recommanded Product: 91-02-1. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Two new dimeric Zn(II) ([{ZnL1(DMSO2)}(2)]center dot DMSO (1), [{(ZnLCl)-Cl-2}(2)] (2)) and a novel tetrameric Zn(II) complex ([(Zn2L3)(2)(mu-OAc)(2)(mu(3)-O)(2)] (3)), where H2L1 = 4-(p-methoxyphenyl) thiosemicarbazone of o-hydroxynapthaldehyde, HL2 = 4-(p-methoxyphenyl)thiosemicarbazone of benzoyl pyridine and H2L3 = 4-(p-chlorophenyl)thiosemicarbazone of o-vanillin are reported. Ligands and their complexes were characterized by spectroscopic and single crystal X-ray diffraction techniques. In addition, the complexes exhibited good binding affinity towards HSA (10(12)M(-1)), which is supported by their ability to quench the tryptophan fluorescence emission spectra of HSA. The complexes were also screened for their DNA binding propensity through UV-vis absorption titration, circular dichroism and fluorescence spectral studies. Results show that they effectively interact with CT-DNA through an intercalative mode of binding, with binding constants ranging from 10(3) to 10(4) M-1. Among the three complexes 1 has the highest binding affinity towards CT-DNA. Further, the phosphatase activity was evaluated using bis(2,4-dinitrophenyl)phosphate (BDNPP) as substrate, however, the complexes did not yield any measurable catalytic activity. Nevertheless the complexes showed significant cytotoxic potential against HeLa and HT-29 cancer cell lines that was assessed through MTT assay and DAPI staining. Remarkably, complex 1 showed better activity than cisplatin against HT-29 cell line.

Recommanded Product: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Saswati; Mohanty, M; Banerjee, A; Biswal, S; Horn, A; Schenk, G; Brzezinski, K; Sinn, E; Reuter, H; Dinda, R or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

SDS of cas: 91-02-1. Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA in [Enamullah, Mohammed; Hossain, Mohammad Anwar; Bindu, Mortuza Mamun; Islam, Mohammad Khairul; Zaman, Mohammad Al-Moktadir] Jahangirnagar Univ, Dept Chem, Dhaka, Bangladesh published Diastereoselection and induced chirality at-metal in distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-copper(PF6)(2) in 2020.0, Cited 41.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

The enantiopure Schiff bases (RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamine (R-1= H and OCH3) are synthesized from reaction between the 2-benzoyl-pyridine andchiral-amine (RorS)-1-(p-R-1-C6H4)ethylamine, respectively. These Schiff bases react with the copper(II) acetate to give distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-Cu(PF6)(2)in the presence of NH4PF6. A conformational change fromcis- totrans-isomer occurs in solution and thereby, the copper(II) coordinates to the solelytrans-form to provide the complexes. Cyclic voltammograms demonstrate two quasi-reversible one electron charge transfer processes for the Cu2+/Cu(+)and Cu+/Cu(0)couples in acetonitrile. ECD spectra reveal expected mirror-image relationships and indicate enantiopurity or enantiomeric excess of theRorS-ligands and their associated complexes in solution. Comparisons of experimental and simulated ECD spectra suggest induced chirality at-metal center, which diastereoselectively provides the Delta-Cu-Ror ?-Cu-Sdiastereomer as major product in solution. DFT/TDDFT optimized structures and excited state properties correspond well to the experimental results.

SDS of cas: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L in PERGAMON-ELSEVIER SCIENCE LTD published article about CAPILLARY ELECTROPHORETIC DETERMINATION; RATIOMETRIC FLUORESCENT; SELECTIVE DETECTION; SO2 DERIVATIVES; SULFUR-DIOXIDE; RAPID DETECTION; RED EMISSION; THIOPHENOLS; BISULFITE; SAMPLES in [Chen, Song; Hou, Peng; Sun, Jingwen; Wang, Haijun; Liu, Lei] Qiqihar Med Univ, Coll Pharm, 333 Bukui St, Qiqihar 161006, Heilongjiang, Peoples R China in 2020.0, Cited 35.0. COA of Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

By taking advantage of the intramolecular charge transfer (ICT) process, we presented a novel fluorescent probe IPY-SO2 based on imidazo[1,5-alpha]pyridine derivative for detecting SO32- with a low detection limit (70 nM). Combining its favorable turn-on fluorescence feature (75-fold), rapid response (5 min), high selectivity, large Stokes shift (174 nm) and low cytotoxicity, IPY-SO2 was successfully applied to imaging SO32 in living MCF-7 cells and zebrafish. (C) 2019 Elsevier B.V. All rights reserved.

COA of Formula: C12H9NO. Welcome to talk about 91-02-1, If you have any questions, you can contact Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Formula: C6H5NO. In 2020.0 CHEM-US published article about MUKAIYAMA-MICHAEL REACTIONS; SILYL ENOL ETHERS; ASYMMETRIC ALDOL; INTERMOLECULAR ADDITION; PROTODEAURATION STEP; EFFICIENT SYNTHESIS; PROPARGYLIC ESTERS; CARBONYL-COMPOUNDS; REACTION 40YEARS; REACTIVITY in [Yuan, Teng; Ye, Xiaohan; Teng, Shun; Wang, Jin; Shan, Chuan; Wojtas, Lukasz; Jean, Jonathan; Shi, Xiaodong] Univ S Florida, Dept Chem, Tampa, FL 33620 USA; [Zhao, Pengyi; Chen, Hao] New Jersey Inst Technol, Dept Chem & Environm Sci, Newark, NJ 07102 USA; [Yi, Yaping] Tsinghua Univ, Dept Chem, Beijing, Peoples R China in 2020.0, Cited 93.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.

A synergistic gold-iron (Au-Fe) catalytic system was developed for sequential alkyne hydration and vinyl Au addition to aldehydes or ketones. Fe(acac)(3) was identified as an essential co-catalyst in preventing vinyl Au protodeauration and facilitating nucleophilic additions. Effective C-C bond formation was achieved under mild conditions (room temperature) with excellent regioselectivity and high efficiency (1% [Au], up to 95% yields). The intramolecular reaction was also achieved, giving successful macrocyclization (16-31 ring sizes) with excellent yields (up to 90%, gram scale) without extended dilution (0.2 M), which highlights the great potential of this new crossed aldol strategy in challenging target molecule synthesis.

Welcome to talk about 500-22-1, If you have any questions, you can contact Yuan, T; Ye, XH; Zhao, PY; Teng, S; Yi, YP; Wang, J; Shan, C; Wojtas, L; Jean, J; Chen, H; Shi, X or send Email.. Formula: C6H5NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem