Day: October 14, 2022

Yang, Guo-Xi; Chen, Yuwen; Zhu, Jie-Ji; Song, Jia-Yu; Tang, Shan-Shun; Ma, Dongge; Tong, Qing-Xiao published the artcile< Rational design of pyridine-containing emissive materials for high performance deep-blue organic light-emitting diodes with CIEy ∼ 0.06>, Reference of 329214-79-1, the main research area is rational design pyridine containing emissive material high performance deep.

Charge balance does matter for emission materials to obtain high-performance organic light-emitting diodes (OLEDs), and it is well-known that the electron-transporting ability is inferior to the hole-transporting for the majority of organic emitting materials, especially for blue-emitting compounds Hence, systematically investigating the effect of the electron-withdrawing group on fluorophore is of vital importance. In this study, we designed and synthesized two deep-blue phenanthro[9,10-d]imidazole (PI) based materials named DPy-PPI and DmPy-PPI by using pyridine-containing groups as electron acceptor as well as adjusting the conjugation length. The photophys., theor., thermal and electrochem. properties of the compounds were investigated systematically, and the relationship between the conjugation length of substituent groups on phenanthroimidazole and the EL performance was clarified. Both of them exhibited good thermal stability and high photoluminescence quantum yields. Non-doped devices based on DPy-PPI and DmPy-PPI as emitter achieved deep-blue emissions with the Commission Internationale de L’Eclairage (CIE) index of (0.14, 0.06) and (0.15, 0.08) and high external quantum efficiencies (EQEmax) of 4.24% and 3.74%, resp. Meanwhile, using DPy-PPI and DmPy-PPI as the host materials, yellow-orange phosphorescent organic light-emitting diodes (PHOLEDs) were fabricated with EQEmax, CEmax and PEmax of 20.55%, 63.86 cd/A, 37.08 lm/W and 18.14%, 55.84 cd/A, 32.47 lm/W, resp. Furthermore, the red PHOLEDs were also constructed using DPy-PPI and DmPy-PPI as the host with EQEmax, CEmax and PEmax of 14.53%, 17.04 cd/A, 18.51 lm/W and 16.62%, 23.58 cd/A, 21.16 lm/W, resp. And we believe this work can provide some insight suggestions for scientific researchers to design deep-blue emitting materials.

Dyes and Pigments published new progress about Blue-emitting electroluminescent devices. 329214-79-1 belongs to class pyridine-derivatives, and the molecular formula is C11H16BNO2, Reference of 329214-79-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wang, Huai-Wei; Qiao, Yu-Han; Wu, Jia-Xue; Wang, Qiu-Ping; Tian, Meng-Xin; Li, Yong-Fei; Yao, Qing-Xia; Li, Da-Cheng; Dou, Jian-Min; Lu, Yi published the artcile< RhIII-Catalyzed C-H (Het)arylation/Vinylation of N-2,6-Difluoroaryl Acrylamides>, Product Details of C11H16BNO2, the main research area is arylboronate difluorophenyl acrylamide rhodium catalyst regioselective diastereoselective arylation; aryl difluorophenyl acrylamide preparation; vinylboronate difluorophenyl acrylamide rhodium catalyst regioselective diastereoselective vinylation; vinyl difluorophenyl acrylamide preparation.

RhIII-catalyzed sp2 C-H cross-coupling of acrylamides with organoboron reactants was accomplished using a com.available N-2,6-difluoroaryl acrylamide auxiliary. A broad range of aryl and vinyl boronates as well as a variety of heterocyclic boronates with strong coordinating ability served as the coupling partners. This transformation proceeded under moderate reaction conditions with excellent functional group tolerance and high regioselectivity.

Organic Letters published new progress about Acrylamides Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 329214-79-1 belongs to class pyridine-derivatives, and the molecular formula is C11H16BNO2, Product Details of C11H16BNO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Croisy-Delcey, Martine; Bisagni, Emile published the artcile< Aza analogs of lucanthone: synthesis and antitumor and bactericidal properties>, Product Details of C9H9Cl2NO2, the main research area is aza analog lucanthone; antitumor lucanthone aza analog; bactericide lucanthone aza analog.

Aza analogs of lucanthone (e.g., I; X = S, NH) were synthesized for evaluation as antitumor drugs. None of the compounds had significant cytotoxic effects on either Friend-tumor or L1210 leukemia cells. However, I (X = NH) had noticeable antibiotic properties.

Journal of Medicinal Chemistry published new progress about Antitumor agents. 86129-63-7 belongs to class pyridine-derivatives, and the molecular formula is C9H9Cl2NO2, Product Details of C9H9Cl2NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Youssef, Heba; Sedykh, Alexander E.; Becker, Jonathan; Schafer, Thomas; Taydakov, Ilya V.; Li, Huanrong R.; Mueller-Buschbaum, Klaus published the artcile< Variable Luminescence and Chromaticity of Homoleptic Frameworks of the Lanthanides together with Pyridylpyrazolates>, Electric Literature of 350-03-8, the main research area is lanthanide pyridylpyrazolate coordination polymer homoleptic framework chromaticity luminescence; rare earth pyridylpyrazolate coordination polymer homoleptic framework chromaticity luminescence; N ligands; coordination polymers; homoleptic; lanthanides; luminescence.

Homoleptic, 3D coordination polymers of the formula 33∞[Ln(3-PyPz)3] and 3∞[Ln(4-PyPz)3], (3-PyPz)- = 3-(3-pyridyl)pyrazolate anion, (4-PyPz)- = 3-(4-pyridyl)pyrazolate anion, both C8H6N3-, Ln = Sm, Eu, Gd, Tb, Dy, were obtained as highly luminescent frameworks by reaction of the lanthanide metals (Ln) with the aromatic heterocyclic amine ligands 3-PyPzH and 4-PyPzH. The compounds form 2 isotypic series of 3D coordination polymers and exhibit fair thermal stability up to 360°. The luminescence properties of all 10 compounds were determined in the solid state, with an antenna effect through ligand-metal energy transfer leading to high efficiency of the luminescence displayed by good quantum yields of up to 74%. The emission is mainly based on ion-specific lanthanide-dependent intra 4f-4f transitions for Tb3+: green, Dy3+: yellow, Sm3+: orange-red, Eu3+: red. For the Gd3+-containing compounds, the yellow emission of ligand triplet-based phosphorescence is observed at room temperature and 77 K. Codoping of the Gd-containing frameworks with Eu3+ and Tb3+ allow further shifting of the chromaticity towards white light emission.

Chemistry – A European Journal published new progress about Color. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Electric Literature of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Xuefu; Ru, Shaoguo; Tian, Hua; Zhang, Suqiu; Lin, Zhenxian; Gao, Ming; Wang, Jun published the artcile< Combined exposure to environmentally relevant copper and 2,2-dithiobis-pyridine induces significant reproductive toxicity in male guppy (Poecilia reticulata)>, Application of C10H8N2S2, the main research area is Poecilia reproductive toxicity dithiobis pyridine copper risk assessment; (PS)(2); Co-exposure; Cu; Ecological safety; Guppy (Poecilia reticulata); Impaired reproduction.

Metal pyrithiones (MePTs), the most widely used biocides in antifouling paints (AFs) coated on the hulls, are usually used in combination with Cu-containing substances. In the aquatic environment, 2,2-dithiobis-pyridine ((PS)2), the main degradation product of MePTs, and Cu usually coexist. However, their combined impacts on aquatic organisms are unclear. This study exposed male guppy (Poecilia reticulata) to an environmentally realistic concentration of Cu (10μg/L) alone or Cu (10μg/L) combined with 20, 200, and 2000 ng/L (PS)2 to explore their combined reproductive toxicity. The results showed that co-exposure to Cu and (PS)2 increased Cu accumulation in the fish body in a dose-dependent manner and induced obvious spermatozoon apoptosis and necrosis, which was mediated by the peroxidation and caspase activation. Compared to Cu alone, co-exposure to Cu and 200, 2000 ng/L (PS)2 significantly decreased the testosterone level and collapsed spermatogenesis, and depressed male sexual interest and mating behavior were observed in three co-exposure groups. Moreover, co-exposure to Cu and (PS)2 increased the disturbance on cyp19a and cyp19b transcription and suppressed the “”display”” reproductive behavior. Eventually, co-exposure to Cu and (PS)2 caused male reproductive failure. Therefore, the concurrence of Cu and (PS)2 induced significant reproductive toxicity in male guppies and would threaten the sustainability of fish populations. Considering the extensive usage of MePTs products in the AFs, their ecol. risk warrants more evaluation.

Science of the Total Environment published new progress about Animal gene Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (cyp19a). 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Application of C10H8N2S2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Meng, Genyi; Guo, Taijie; Ma, Tiancheng; Zhang, Jiong; Shen, Yucheng; Sharpless, Karl Barry; Dong, Jiajia published the artcile< Modular click chemistry libraries for functional screens using a diazotizing reagent>, Computed Properties of 56622-54-9, the main research area is alkyl aryl azide triazole chemoselective preparation; fluorosulfonyl azide generation chemoselective diazotization primary amine; combinatorial generation library alkyl aryl azide cycloaddition alkyne; functional screen click chem azide generated in situ.

Alkyl and aryl azides were prepared from the corresponding primary alkyl and aryl amines by reaction with fluorosulfonyl azide generated in situ from a fluorosulfonylimidazolium triflate and sodium azide, expanding access to azides and both to the 1,2,3-triazoles derived from them and to functional screens employing them. The method allowed the preparation of a library of >1000 azides from the corresponding amines; the azide library underwent copper-catalyzed azide-alkyne cycloaddition reactions to yield a library of >1000 1,2,3-triazoles.

Nature (London, United Kingdom) published new progress about Alkyl azides Role: CMB (Combinatorial Study), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 56622-54-9 belongs to class pyridine-derivatives, and the molecular formula is C7H10N2, Computed Properties of 56622-54-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ozturkkan Ozbek, Fureya Elif; Ugurlu, Guventurk; Kalay, Erbay; Necefoglu, Hacali; Hokelek, Tuncer published the artcile< Theoretical and experimental assessment of structural, spectroscopic, electronic and nonlinear optical properties of two aroylhydrazone derivative>, Related Products of 93-60-7, the main research area is structural spectroscopic electronic nonlinear optical property aroylhydrazone derivative.

Two aroylhydrazone, N’-(pyridine-4-ylmethylene)nicotic acid hydrazide (1) and N’-(pyridine-3-ylmethylene)nicotic acid hydrazide (2), were synthesized and their structures were determined by single-crystal X-ray diffraction anal. The X-ray anal. indicated that the compound 1 was crystallized in triclinic crystal system with P -1 space group a = 8.7899 (2) Å, b = 10.8983 (3) Å, c = 11.7726 (3) Å, α= 89.952 (3)°, β = 88.684 (3)°, γ= 75.293 (2)°, V = 1090.50 (5) Å3 and Z = 4 and compound 2 was crystallized in monoclinic crystal system with P21/c space group, a = 11.9239 (3) Å, b = 8.6495 (2) Å, c = 11.1021 (3) Å, α= 90 (3)°, β = 111.664 (3) (3)°, γ= 90°, V = 1064.14 (5) Å3 and Z = 4. Intermol. interactions of the compounds were determined by Hirhfeld Surface Anal. The H ··· H interactions with 37.9% (for compound 1) and 37.5% (for compound 2) contributions are the most important interactions to the overall crystal packings. FT-IR, Raman, 1H and 13C NMR and UV-Vis spectroscopy methods were used for spectroscopic characterization of the compounds The spectroscopic properties of the compounds were calculated theor. by using D. Functional Theory (DFT) with B3LYP and ab initio Hartree-Fock (HF) methods at different basis sets. A correlation was found between the theor. and exptl. values for the spectroscopic results. Moreover, the HOMO (HOMO), the LUMO (LUMO), elec. dipole moment (μ), polarizability (α) and hyperpolarizability (β) of the compounds were computed both DFT/B3LYP/6-311++G(d,p) and ab initio HF/6-311++G(d,p) methods. The calculated first hyperpolarizability value at the DFT/B3LYP/6-31++G (d,p) level of compound 1 with dimer structure is 18.14 times larger than urea, the standard nonlinear optical material. So, this value implies that compound 1 considered have potential candidates for designing high quality nonlinear optical materials. The energy gap (ΔEgap) and Mol. Electrostatic Potential (MEP) of the compounds were investigated. The structural and vibration frequency values calculated theor. were compared with the exptl. values.

Journal of Molecular Structure published new progress about Band gap. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hu, Chaopeng; Zhang, Jianying; Yang, Hao; Guo, Lulu; Cui, Chunming published the artcile< Synthesis of Cationic Silaamidinate Germylenes and Stannylenes and the Catalytic Application for Hydroboration of Pyridines>, HPLC of Formula: 350-03-8, the main research area is cationic silaamidinate germylene stannylene preparation catalyst hydroboration pyridine; crystal structure cationic silaamidinate germylene stannylene; mol structure cationic silaamidinate germylene stannylene; silaamidine deprotonation reaction germanium tin chloride.

The N-heterocyclic germylenes and stannylenes LSi(NAr)2EX (L = PhC(NtBu)2, Ar = 2,6-iPr2C6H3; E = Ge, Sn; X = Cl, CF3SO3, BPh4) supported by the bulky silaamidinate ligand [LSi(NAr)2]- were synthesized and fully characterized. The germylene triflate LSi(NAr)2GeOTf (3b) and dimeric borate [LSi(NAr)2Ge]2ClBPh4 (3a) enabled highly regio- and chemoselective catalytic hydroboration of pyridines and may represent the most active catalytic system for the transformation. DFT calculations disclosed that the cationic germylene [LSi(NAr)2Ge]+ with a low-lying LUMO energy initiated the catalytic process. In contrast, the analogous amidinate germylene triflates are almost inactive, indicating the silaamidinate ligand is essential for the stabilization of cationic species.

Inorganic Chemistry published new progress about Amidination. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, HPLC of Formula: 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cheng, Yin-Jia; Qin, Si-Yong; Ma, Yi-Han; Chen, Xiao-Sui; Zhang, Ai-Qing; Zhang, Xian-Zheng published the artcile< Super-pH-Sensitive Mesoporous Silica Nanoparticle-Based Drug Delivery System for Effective Combination Cancer Therapy>, Product Details of C10H8N2S2, the main research area is peptide doxorubicin silica nanoparticle tumor antitumor; charge-reversal; combinational tumor therapy; mesoporous silica nanoparticles; multifunctional peptide; redox-sensitive drug release.

A multifunctional nanoplatform based on mesoporous silica nanoparticles (MSNs) was developed for combinational tumor therapy. Doxorubicin (DOX) was chosen as an antitumor drug and loaded into mesopores of MSNs via phys. absorption. Then, a tumor-targeted fusion peptide conjugated with 2,3-dimethylmaleic anhydride (DTCPP) and a therapeutic peptide conjugated with 2,3-dimethylmaleic anhydride (DTPP) were introduced to the surface of MSNs as super-pH-sensitive nanovalves through disulfide linkages. The BSA adsorption assay confirmed the charge-reversal property of MSN-ss-DTPP&DTCPP nanoparticles at slightly acidic condition (pH 6.8) and superior stability in physiol. environment (pH 7.4). According to the drug release research, both glutathione (GSH) and acidic condition are required for the accelerated drug release from DOX@MSN-ss-DTPP&DTCPP nanoparticles. Moreover, in vitro studies demonstrated the significantly reinforced tumor cellular uptake efficiency and mitochondrial disruption ability of DOX@MSN-ss-DTPP&DTCPP nanoparticles in tumor environment, in which DOX@MSN-ss-DTPP&DTCPP nanoparticles exhibited the preferred cytotoxicity toward αvβ3-pos. human cervical carcinoma (HeLa) cells. We believe that the multifunctional dual-stimuli-sensitive MSN could provide an effective strategy for combinational tumor therapy.

ACS Biomaterials Science & Engineering published new progress about Antitumor agents. 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Product Details of C10H8N2S2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bazyar, Zahra; Tavakoliana, Mina; Hosseini-Sarvari, Mona published the artcile< Au-Pd@ZnO alloy nanoparticles: a promising heterogeneous photocatalyst toward decarboxylative trifluoromethylation under visible-light irradiation>, Electric Literature of 3796-23-4, the main research area is trifluoromethyl arene preparation; carboxylic acid decarboxylative trifluoromethylation palladium gold alloy nanoparticle photocatalyst.

Considering the high synergistic effect of Pd and Au supported on semiconductors, herein, Au-Pd@ZnO was synthesized and characterized with high potential toward the decarboxylative trifluoromethylation of aromatic carboxylic acids RCOOH (R = Ph, 1-naphthyl, benzthiophen-2-yl, etc.). Moreover, the combination of pyridine N-oxide and trifluoroacetic anhydride as a cost-effective and easy-to-handle source of CF3 could successfully generate the trifluoromethyl radical in the presence of the photocatalyst. To shed light on the synergistic effect of Pd and Au various control experiments were conducted, indicating the crucial role of both of them. This protocol was applicable to different aromatic and heteroaromatic compounds to deliver desired adducts in moderate to good yields and high functional group tolerance. Au-Pd@ZnO not only exhibited high catalytic performance but can also be recovered three times.

New Journal of Chemistry published new progress about Aromatic carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Electric Literature of 3796-23-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem