Day: October 24, 2022

In 2017,Mohammad, Akbar; Chandra, Prakash; Ghosh, Topi; Carraro, Mauro; Mobin, Shaikh M. published 《Facile Access to Amides from Oxygenated or Unsaturated Organic Compounds by Metal Oxide Nanocatalysts Derived from Single-Source Molecular Precursors》.Inorganic Chemistry published the findings.SDS of cas: 103-74-2 The information in the text is summarized as follows:

Oxidative amidation is a valuable process for the transformation of oxygenated organic compounds to valuable amides. However, the reaction is severely limited using an expensive catalyst and limited substrate scope. To circumvent these limitations, designing a transition-metal-based nanocatalyst via more straightforward and economical methodol. with superior catalytic performances with broad substrate scope is desirable. To resolve the aforementioned issues, the authors report a facile method for the synthesis of nanocatalysts NiO and CuO by the sol-gel-assisted thermal decomposition of [Ni(hep-H)(H2O)4]SO4 (SSMP-1) and [Cu(μ-hep)(BA)]2 (SSMP-2) [hep-H = 2-(2-hydroxylethyl)pyridine; BA = HOBz] as single-source mol. precursors (SSMPs) for the oxidative amidation of benzyl alc., benzaldehyde, and BA by using DMF as the solvent and as an amine source, in the presence of tert-butylhydroperoxide (TBHP) as the oxidant, at T = 80°. In addition to nanocatalysts NiO and CuO, the authors’ previously reported Co/CoO nanocatalyst (CoNC), derived from [CoII(hep-H)(H2O)4]SO4 (A) as an SSMP, was also explored for the aforementioned reaction. Also, the authors have carefully studied the difference in the catalytic performance of Co-, Ni-, and Cu-based nanoparticles synthesized from the SSMP for the conversion of various oxygenated and unsaturated organic compounds to their resp. amides. CuO showed an optimum catalytic performance for the oxidative amidation of various oxygenated and unsaturated organic compounds with a broad reaction scope. Finally, CuO can be recovered unaltered and reused for several (six times) recycles without any loss in catalytic activity. In the experimental materials used by the author, we found 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2SDS of cas: 103-74-2)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.SDS of cas: 103-74-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,ACS Omega included an article by Oppong-Quaicoe, Anita A.; DeBoef, Brenton. Formula: C6H6BrN. The article was titled 《FeCl2-Mediated Rearrangement of Allylic Alcohols》. The information in the text is summarized as follows:

Aryllithium reagents underwent one-pot regioselective addition and rearrangement reactions with cyclic α,β-unsaturated ketones and an acyclic diaryl-α,β,γ,δ-dienone in the presence of FeCl2 to yield cyclic secondary β-arylallylic alcs. Addition of an arylithium to an α’-methyl-α,β-enone followed by FeCl2-mediated rearrangement of the mixture of diastereomers indicated that the rearrangement is stereoselective.2-Bromo-5-methylpyridine(cas: 3510-66-5Formula: C6H6BrN) was used in this study.

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Formula: C6H6BrN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,New Journal of Chemistry included an article by Das, Suman; Bhattacharjee, Jayeeta; Panda, Tarun K.. SDS of cas: 100-48-1. The article was titled 《An imidazolin-2-iminato ligand organozinc complex as a catalyst for hydroboration of organic nitriles》. The information in the text is summarized as follows:

The reaction of diethylzinc with imidazolin-2-imines (ImRNH, R = Dipp (2,6-diisopropylphenyl)), Mes (2,4,6-trimethylphenyl), and tBu (tert-butyl) afforded the corresponding dimeric Zn(II) imidazolin-2-iminato complexes [{(ImRN)ZnEt}2] (R = Dipp, 1a; R = Mes, 1b; R = tBu, 1c). The Zn complexes were characterized using spectroscopic techniques and the mol. structure of complex 1b was established by single-crystal x-ray diffraction anal. Complex 1c was used as a catalyst for the chemoselective hydroboration of organic nitriles with pinacolborane (HBpin) at ambient temperature to obtain diborylamines of a broad substrate scope in high yield. Zn complex 1c exhibits a versatile substrate scope and good functional group tolerance for catalytic hydroboration reactions. A most plausible mechanism is proposed from the kinetic study. In the experiment, the researchers used many compounds, for example, 4-Cyanopyridine(cas: 100-48-1SDS of cas: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.SDS of cas: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Science China: Chemistry included an article by Miao, Meng; Liao, Li-Li; Cao, Guang-Mei; Zhou, Wen-Jun; Yu, Da-Gang. Recommanded Product: 100-48-1. The article was titled 《Visible-light-mediated external-reductant-free reductive cross coupling of benzylammonium salts with (hetero)aryl nitriles》. The information in the text is summarized as follows:

A novel visible-light-mediated external reductant-free reductive cross coupling for the construction of C sp2-C sp3 bonds was reported. A variety of benzylammonium salts RCH(R1)N+(CH3)3O-S(O)2CF3 (R = naphthalen-2-yl, 1-benzothiophen-3-yl, 4-tert-butylphenyl, etc.; R1 = H, Me, n-Pr) and 1,2,3,4-tetrahydro-N,N,N-trimethyl-1-naphthalenaminium 1,1,1-trifluoromethanesulfonate underwent selective coupling with (hetero)aryl nitriles R2CN (R2 = 4-cyano-3-methylphenyl, 2-phenylpyridin-4-yl, isoquinolin-1-yl, etc.) to deliver important diarylmethanes RCH(R1)R2 and 4-(1,2,3,4-tetrahydronaphthalen-1-yl)benzonitrile under mild reaction conditions. Importantly, photocatalysts can be omitted for many cases, which might involve the electron donor acceptor (EDA) complex. Mechanistic studies indicated that benzylic radicals might be involved as the key intermediates. Moreover, the in situ NMe3 generated via cleavage of C-N bond in ammonium salts acts as the electron donor, thus avoiding the use of external-reductant. In the experimental materials used by the author, we found 4-Cyanopyridine(cas: 100-48-1Recommanded Product: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Molecular-level design of Fe-N-C catalysts derived from Fe-dual pyridine coordination complexes for highly efficient oxygen reduction》 were Zhang, Xiaoran; Mollamahale, Yaser Bahari; Lyu, Dandan; Liang, Lizhe; Yu, Feng; Qing, Ming; Du, Yonghua; Zhang, Xinyi; Tian, Zhi Qun; Shen, Pei Kang. And the article was published in Journal of Catalysis in 2019. Reference of 2,6-Diaminopyridine The author mentioned the following in the article:

Iron-nitrogen-carbon (Fe-N-C) materials as the most promising non-precious metal catalysts for oxygen reduction reaction (ORR) to replace Pt-based catalysts are in high demand for large scale application of fuel cells. However, their activity and durability are still critical issues. Development of Fe/N/C-containing precursors is a straightforward strategy for obtaining advanced Fe-N-C ORR catalysts to address these issues. Herein, we report an advanced Fe-N-C catalyst with a hybrid structure of single Fe atom sites (Fe-Nx moieties) and exposed Fe carbides/nitrides nanodots with diameters <2 nm embedded onto highly graphitic N-doped carbon matrix. The catalyst is synthesized by pyrolysis of a new kind of Fe-dual pyridine coordinated complex as the precursor. This facile chem. route results in a non-conventional Fe-N-C catalyst with encapsulated Fe-metallic phase nanoparticles or Fe-Nx moieties. The catalyst exhibits excellent ORR activity and remarkable durability in both acidic and alk. media. Its onset and half-wave potentials are 1.08 V and 0.88 V vs. (RHE) in 0.1 M KOH, resp., and 0.95 V and 0.81 V vs. RHE, resp., in 0.5 M H2SO4. Furthermore, a single proton exchange membrane (PEM) fuel cell fabricated by our catalyst generates the output power of 0.65 W cm-2, which indicates great potential of our hybrid structured Fe-N-C catalyst for the practical application in fuel cells. In the experiment, the researchers used many compounds, for example, 2,6-Diaminopyridine(cas: 141-86-6Reference of 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Reference of 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Construction of Nitrogen-containing Polycyclic Aromatic Compounds by Intramolecular Oxidative C-H/C-H Coupling of Bis(9H-carbazol-9-yl)benzenes and Their Properties》 were Taniguchi, Taisei; Itai, Yuhei; Nishii, Yuji; Tohnai, Norimitsu; Miura, Masahiro. And the article was published in Chemistry Letters in 2019. Category: pyridine-derivatives The author mentioned the following in the article:

Treatment of 1,3- and 1,4-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)benzenes with an oxidizing system of Pd(II)/Ag(I) has been found to induce double intramol. C-H/C-H coupling to give the corresponding highly π-extended polycyclic compds I (X = CH, N), II and III. In contrast, a singly cyclized product IV in a different manner has been isolated from the reaction of 1,2-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)benzene. Cardinal optoelectronic properties of the products have also been estimated2,6-Dibromopyridine(cas: 626-05-1Category: pyridine-derivatives) was used in this study.

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Decarboxylative Hydroalkylation of Alkynes via Dual Copper-Photoredox Catalysis》 was published in ACS Catalysis in 2020. These research results belong to Mastandrea, Marco M.; Canellas, Santiago; Caldentey, Xisco; Pericas, Miquel A.. Recommanded Product: 2510-22-7 The article mentions the following:

A photoredox strategy for the synthesis of a wide range of allylic amines and ethers from carboxylic acids and alkynes has been developed. This approach relies on the perturbation of the ground-state electronic properties of terminal alkynes through the formation and photoexcitation of copper acetylide intermediates. This process takes place through cooperative copper and organic photoredox catalysis and can be carried out in a stereodivergent manner. Thus, a systematic multivariate HTE screening spotlighted that a switch in the stereochem. outcome can be provoked by choosing an appropriate combination of ligand and base. The developed methodol. has been applied to the stereoselective coupling of primary, secondary, and tertiary alkyl radicals with (hetero)aromatic terminal alkynes. As an addnl. practicality, similar reaction conditions allowed for the use of aromatic amines as radical precursors in a cross dehydrogenative coupling for the direct vinylation of inactivated C-H bonds. In the experiment, the researchers used 4-Ethynylpyridine(cas: 2510-22-7Recommanded Product: 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Design, synthesis, characterization of peripherally tetra-pyridine-triazole-substituted phthalocyanines and their inhibitory effects on cholinesterases (AChE/BChE) and carbonic anhydrases (hCA I, II and IX)》 was published in Dalton Transactions in 2020. These research results belong to Arslan, Tayfun; Bugrahan Ceylan, M.; Bas, Huseyin; Biyiklioglu, Zekeriya; Senturk, Murat. Quality Control of 4-Ethynylpyridine The article mentions the following:

In this study, phthalocyanine precursors (5 and 9) and 1,2,3-triazole-substituted metal-free and metallo phthalocyanines (9a-c) were designed and synthesized for the first time and evaluated in vitro for key mol. targets. The structures of the novel compounds were characterized via FT-IR, 1H/13C NMR, UV-Vis, and mass spectroscopy. The inhibitory activities of the compounds were tested against human carbonic anhydrase isoforms hCA I, II (cytosolic, ubiquitous isoenzymes), and IX (transmembrane, cancer-associated isoenzyme) and cholinesterases (AChE and BChE, which are associated with Alzheimer’s disease). Among the three phthalocyanines and starting compounds, 9b showed the most interesting profile as a nanomolar selective inhibitor of hCA I (Ki = 37.2 nM) and 9c showed the most effective inhibitory effect on hCA II, IX, AChE and BChE (Ki = 41.9, 27.4, 5.8 and 45.8 nM, resp.). This study is also the first example of cancer-associated isoenzyme hCA IX inhibition by phthalocyanines. The experimental process involved the reaction of 4-Ethynylpyridine(cas: 2510-22-7Quality Control of 4-Ethynylpyridine)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Quality Control of 4-Ethynylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Mechanosynthesis of Noels-type NHC-Ruthenium Complexes and Applications in Ring-Opening Metathesis Polymerization》 was published in Organometallics in 2020. These research results belong to Quintin, Francois; Pinaud, Julien; Lamaty, Frederic; Bantreil, Xavier. Synthetic Route of C6H7Br2N The article mentions the following:

The use of ball-mills enabled the efficient mechanosynthesis of a variety of N-aryl,N-alkyl imidazolium salts and of corresponding NHC Ag(I) complexes. Transmetalation with Ru via mechanochem. allowed the rapid access (1.5 min to 1 h) to complexes having a similar structure to Noels-type precatalysts. Evaluation of the complexes in the ring-opening metathesis polymerization of norbornene in different solvent, including nontoxic ones, showed a high catalytic activity for one of them, comparable to the one of Noels catalyst.2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Synthetic Route of C6H7Br2N) was used in this study.

2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Synthetic Route of C6H7Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Acylation of 2-benzylpyridine N-oxides and subsequent in situ [3,3]-sigmatropic rearrangement reaction》 was published in Tetrahedron Letters in 2020. These research results belong to Jing, Hua-qing; Li, Hong-liang; Antilla, Jon C.. Application In Synthesis of 2-Bromo-5-methylpyridine The article mentions the following:

An effective method for the acylation of 2-benzylpyridine N-oxides and their fast in situ [3,3]-sigmatropic rearrangement was reported. This transformation has a wide substrate scope under mild conditions, giving moderate to excellent yields. The application for the synthesis of chiral phenyl-2-pyridylmethanol products was briefly explored. Furthermore, an interesting example of tandem substitution and in situ [3,3]-sigmatropic rearrangement of 2-benzylpyridine N-oxide with benzenecarboximidoyl chloride was reported. In addition to this study using 2-Bromo-5-methylpyridine, there are many other studies that have used 2-Bromo-5-methylpyridine(cas: 3510-66-5Application In Synthesis of 2-Bromo-5-methylpyridine) was used in this study.

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Application In Synthesis of 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem