Month: October 2022

Liu, Shengrong; Chen, Ming; Cao, Xiaoqiang; Li, Guang; Zhang, Di; Li, Mingzhen; Meng, Na; Yin, Jieji; Yan, Bingqi published the artcile< Chromium (VI) removal from water using cetylpyridinium chloride (CPC)-modified montmorillonite>, Reference of 123-03-5, the main research area is chromium removal water cetylpyridinium chloride modified montmorillonite.

Montmorillonite (Mt) has been used widely for metal removal from water and wastewater due to its various advantages including low cost, large surface area, high structure stability, and high ion exchange capacity. However, the removal of anionic hexavalent chromium (Cr) using Mt is inhibited by the neg. charges on the adsorbent. To enhance Cr (VI) adsorption on Mt, a cationic surfactant – cetylpyridinium chloride (CPC) – was utilized to modify the interlayer surface of Mt. Fourier-transform IR spectroscopy and X-ray diffraction were performed to characterize the CPC modified Mt (CPC-Mt) and the structure change of Mt. Studies have shown that CPC intercalated into Mt interlayers via electrostatic interaction between Mt and CPC, as well as the hydrophobic interaction among CPC mols. After modification, the CPC-Mt showed a pos. zeta potential at pH 2-11; while the sp. surface area decreased, CPC effectively increased the interlayer distance of Ca-Mt, with a maximum d001 value of 4.37 nm, and provided more exchange sites for Cr (VI) adsorption. Cr (VI) was efficiently removed using CPC-Mt at low pH values, but the removal was influenced adversely by the increase of pH and ionic strength. The adsorption process was described by a Langmuir isotherm model with the constant of 0.342 L/mg and the maximum adsorption capacity of 43.84 mg/g at 298 K, and by a pseudo-second order kinetic model with a kinetic coefficient of 6.62 g/(mg·min). The adsorption mechanism anal. has shown that electrostatic attraction is the main mechanism for Cr (VI) removal; at the same time, the reduction of Cr (VI) to Cr (III) by Fe (II) in Mt cannot be neglected at low pH values, which increased Cr removal and was confirmed by the X-ray photoelectron spectroscopic anal.

Separation and Purification Technology published new progress about Adsorbents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Reference of 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hsu, Day-Shin; Wang, Meng-Yu; Huang, Jiun-Yi published the artcile< Asymmetric Total Syntheses of (+)-5-epi-Schisansphenin B and the Proposed Structure of (+)-15-Hydroxyacora-4(14),8-diene>, Reference of 1416819-91-4, the main research area is Heck alkenylation Stetter Tiffeneau Demjanov enantioselective diastereoselective regioselective; epi schisansphenin B total synthesis; hydroxyacoradiene total synthesis.

The asym. total syntheses of (+)-5-epi-schisansphenin B and the proposed structure of (+)-15-hydroxyacora-4(14),8-diene have been accomplished from 1,3-cyclopentadione in eight synthetic steps. The enantioselective palladium-catalyzed redox-relay Heck alkenylation, the intramol. Stetter reaction, and the regioselective Tiffeneau-Demjanov-type ring expansion were the pivotal steps in these syntheses.

Journal of Organic Chemistry published new progress about Alkenylation, stereoselective (redox-relay Heck). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Reference of 1416819-91-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mihajlovic-Lalic, Ljiljana E.; Stankovic, Dalibor; Novakovic, Irena; Grguric-Sipka, Sanja published the artcile< (Electro)chemical and antimicrobial characterization of novel Ru(II) bipyridine complexes with acetylpyridine analogs>, Related Products of 350-03-8, the main research area is ruthenium bipyridine acetylpyridine complex preparation antibacterial antifungal antioxidant; DNA intercalation ruthenium bipyridine acetylpyridine complex.

Three ruthenium-bipyridine complexes (1-3) carrying acetylpyridine ligand unit were synthesized in methanol via the reaction of [RuCl2(bpy)2] with corresponding acetylpyridine (2-, 3-, and 4-acpy). Obtained complexes were characterized by (1H and 13C) NMR and IR spectroscopy, MS spectrometry, UV-visible spectrophotometry, and cyclic voltammetry. Their structural characterization revealed bidentate coordination mode for 2-acpy while 3- and 4-acpy acted as monodentate ligands. The electrochem. profile of newly synthesized compounds was studied by cyclic voltammetry which confirmed their electrochem. activity. Voltammetric responses within the -1.20 < Ep < 1.50 v range of potentials were summarized in two major events: Ru(II)→Ru(III) oxidation spotted at apparatus ΔEp = 0.65 v and successive reductions of bpy units located from -0.79 v to 0.47 v (vs. Ag/AgCl (3 M) electrode). The DNA-binding activity of the complexes was evaluated by both UV-visible spectrophotometry and cyclic voltammetry indicating DNA-intercalation with a slight contribution of electrostatic interactions. Furthermore, antimicrobial activity was tested against bacterial and fungal strains, for which moderate activity was observed Assessment of in vitro toxicity against freshly hatched nauplii of Artemia salina as well as radical scavenging capacity was evaluated. The test compounds showed neither toxicity nor antioxidant activity. Journal of Coordination Chemistry published new progress about Antibacterial agents. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Related Products of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco; Bartoli, Donatella; Massoli, Alberto published the artcile< The reactions of some halogenated pyridines with methoxide and methanethiolate ions in dimethylformamide>, Application of C6H6ClNO, the main research area is pyridine dihalo substitution methoxide alkanethiolate; halopyridine substitution methoxide alkanethiolate; substitution dihalopyridine methoxide alkanethiolate; mercaptopyridine; alkylthiopyridine.

Dihalopyridines I (R = 2-Br, R1 = 5-, 6-Br; R = 2-, 5-Cl, R1 = 3-Cl) reacted with NaSR2 (R2 = Me, CHMe2) in DMF to give 73-96% mono- or bis-substitution products I (R = SR2) or I (R = R1 = SR2), depending upon reaction conditions. The dihalo compounds reacted with NaOMe to give 72-93% I (R = OMe), but bis-substitution occurred easily only for I (R = 2-Br, R1 = 6-Br; R = 5-Cl, R1 = 3-Cl). Some I [R(R1) = OMe, R1(R) = SMe] were prepared by further reaction of monosubstitution products. I (R = R1 = SCHMe2 were fragmented by Na-HMPA to give I (R = R1 = SH), which were isolated as I (R = R1 = SMe) in 63-80% yield.

Tetrahedron published new progress about Nucleophilic aromatic substitution reaction. 13472-84-9 belongs to class pyridine-derivatives, and the molecular formula is C6H6ClNO, Application of C6H6ClNO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Liang, Apeng; Li, Xinjian; Liu, Dongfeng; Li, Jingya; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng published the artcile< The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters>, Name: 2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, the main research area is aryl boronic acid ester trifluoroethyl iodide cross coupling palladium; heteroaryl boronic acid ester trifluoroethyl iodide cross coupling palladium; trifluoroethyl arene preparation; palladium cross coupling catalyst.

The cross-coupling reactions of 1,1,1-trifluoro-2-iodoethane with aryl and heteroaryl boronic acid esters have been successfully achieved. The new protocol allows for a convenient introduction of trifluoroethyl groups into a variety of aryl and heteroaryl moieties under mild conditions.

Chemical Communications (Cambridge, United Kingdom) published new progress about Boronic acids, esters Role: RCT (Reactant), RACT (Reactant or Reagent) (aryl/heteroaryl). 832735-54-3 belongs to class pyridine-derivatives, and the molecular formula is C18H22BNO3, Name: 2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Koovits, Paul J.; Dessoy, Marco A.; Matheeussen, An; Maes, Louis; Caljon, Guy; Mowbray, Charles E.; Kratz, Jadel M.; Dias, Luiz C. published the artcile< Structure-activity relationship of 4-azaindole-2-piperidine derivatives as agents against Trypanosoma cruzi>, Synthetic Route of 1050501-88-6, the main research area is azaindole piperidine structure activity relationship trypanosoma cruzi chagas disease; Azaindole; Chagas disease; Drug discovery; Neglected diseases.

The structure-activity relationship of a 4-Azaindole-2-piperidine compound selected from GlaxoSmithKline’s recently disclosed open-resource “”Chagas box”” and possessing moderate activity against Trypanosoma cruzi, the parasite responsible for Chagas disease, is presented. Despite considerable medicinal chem. efforts, a suitably potent and metabolically stable compound could not be identified to advance the series into in vivo studies. This research should be of interest to those in the area of neglected diseases and in particular anti-kinetoplastid drug discovery.

Bioorganic & Medicinal Chemistry Letters published new progress about Chagas disease. 1050501-88-6 belongs to class pyridine-derivatives, and the molecular formula is C5H4BrClN2, Synthetic Route of 1050501-88-6.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gao, Kaige; Liu, Chunlin; Zhang, Wei; Wang, Kangni; Liu, Wenlong published the artcile< Pyroelectricity and fieldinduced spin-flop in 4-(aminomethyl)pyridinium manganese chloride dihydrate>, Quality Control of 3731-53-1, the main research area is aminomethyl pyridinium manganese chloride dihydrate pyroelectricity spinflop; ferroelectric; pyroelectric; single crystal; spin-flop.

Large single crystals of (4-(Aminomethyl)pyridinium)2 MnCl4 • 2H2O (1) were grown by slow evaporation of solution The crystal structure was solved to be Pi, which belongs to the ̅central sym. space group. But small pyroelec. current was detected, as well as a ferroelec. hysteresis loop. The pyroelec. and the ferroelec. properties were attributed to the strain caused by defects. Temperature-dependent magnetic curves and the M-H curve show that 1 is antiferromagnetic ordering below 2.5 K. A field-induced spin-flop is observed in the antiferromagnetic ordering state.

Royal Society Open Science published new progress about Antiferromagnetic films. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Quality Control of 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wu, Datong; Pan, Fei; Gao, Li; Tao, Yongxin; Kong, Yong published the artcile< An ionic-based carbon dot for enantioselective discrimination of nonaromatic amino alcohols>, Synthetic Route of 3731-53-1, the main research area is fluorescent sensor amino alc copper binding energy chiral recognition.

Here, ionized chiral carbon dots, (S,S)-C-dots-1 (λex = 430 nm, λem = 480 nm), were synthesized via a facile route with relatively high quantum yield (~24.4%) and used as a fluorescent chiral sensor. One of the advantages of the synthetic process is that it avoids the loss of the chiral center. That is, the chiral bromo compound can directly form an ionic pair with the pyridyl group, which is derived from the amine precursor in the first step. Furthermore, (S,S)-C-dots-1 shows clear discrimination toward different configurations of nonaromatic amino alcs. in the presence of Cu(II). When the (R)-isomer is added to a solution of (S,S)-C-dots-1 + Cu(II), it shows much higher fluorescent intensity than the (S)-isomer. The values of IR/IS are 2.9 and 2.3 for 2-aminobutan-1-ol and 2-aminopropan-1-ol, resp. In summary, we believe that this work can expand the synthetic routes and potential applications of functional carbon dots in the field of enantioselective sensing.

Analyst (Cambridge, United Kingdom) published new progress about Amino alcohols Role: ANT (Analyte), PEP (Physical, Engineering or Chemical Process), PRP (Properties), ANST (Analytical Study), PROC (Process). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Synthetic Route of 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tamang, Sem Raj; Singh, Arpita; Bedi, Deepika; Bazkiaei, Adineh Rezaei; Warner, Audrey A.; Glogau, Keeley; McDonald, Corey; Unruh, Daniel K.; Findlater, Michael published the artcile< Polynuclear lanthanide-diketonato clusters for the catalytic hydroboration of carboxamides and esters>, Category: pyridine-derivatives, the main research area is amine preparation; carboxamide hydroboration lanthanide diketonato cluster catalyst; tetramethyl dioxaborolane preparation.

The direct deoxygenation of carboxamides RC(O)N(R1)R2 [R = H, Ph, thiophen-2-yl, naphthalen-2-yl, etc.; R1 = H, Me, Et, (CH2)4CH3, iso-Pr, Ph, benzyl; R2 = H, Me, Et, isopropyl; R1R2 = (CH2)5, (CH2)2O(CH2)2] using earth-abundant lanthanum catalysts in the presence of HBpin presents good to excellent yields with broad substrate scope and functional group/heteroatom tolerance. Moreover, this method is also effective in catalyzing the hydroboration of esters R3C(O)OR4 [R3 = Ph, cyclohexyl, (CH2)6CH3, pyridin-3-yl, etc.; R4 = Me, Et, naphthalen-2-yl, 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl, etc.]. Finally, selective cleavage of the amide group bonds (C-N vs. C-O) could be achieved based on the nature of the nitrogen substituents. Catalytic reduction of carboxamides into their corresponding amines RCH2N(R1)R2 is attractive but extremely challenging transformation, which often meets with limited success; the valuable amine products drive ongoing research in this area.

Nature Catalysis published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Luo, Lihua; Tang, Juan; Sun, Rui; Li, Wenjing; Zheng, Xueli; Yuan, Maoling; Li, Ruixiang; Chen, Hua; Fu, Haiyan published the artcile< Direct C-H Sulfonylimination of Pyridinium Salts>, Recommanded Product: 2,4-Bipyridine, the main research area is sulfonyl iminopyridine preparation; pyridinium salt arylsulfonyl azide sulfonylimination.

A direct pyridinium C-H sulfonylimination has been developed for the synthesis of sulfonyl iminopyridine derivatives I (R = H, CN, Ph, thiophen-2-yl, etc.; R1 = H, OMe, Ph, thiophen-3-yl, etc.; R2 = H, cyclopropyl, Ph, 4-bromophenyl, etc.; R1R2 = -CH=CH-CH=CH-; R3 = Me, Et, i-Pr, etc.; R4 = Et, Ph, pyridin-3-yl, etc.) with high efficiency. This transformation features the direct and efficient formation of a C=N bond with a high functional group tolerance under metal-free conditions. The spectroscopic properties potentially enable these sulfonyl iminopyridine compounds I to be useful new emitting materials.

Organic Letters published new progress about Azides, sulfonyl azides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 581-47-5 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Recommanded Product: 2,4-Bipyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem