Month: October 2022

Hu, Jun-Chao; Sun, Shanshan; Li, Ming-De; Xia, Wu; Wu, Jin; Liu, Hongfang; Wang, Feng published the artcile< A biomimetic self-assembled cobaloxime@CdS/rGO hybrid for boosting photocatalytic H2 production>, Synthetic Route of 3731-53-1, the main research area is biomimetic cobaloxime CdS rGO hybrid photocatalytic hydrogen prduction.

A biomimetic CoPe@CdS/rGO hybrid that self-assembles via the integration of a mol. cobalt catalyst and CdS nano-semiconductor on reduced graphene oxide was constructed for boosting photocatalytic H2 production Photoinduced electron transfer from CdS/rGO to the mol. catalyst occurs and a long-lived charge-separation state forms for high H2 production

Chemical Communications (Cambridge, United Kingdom) published new progress about Attenuated-total-reflectance IR spectroscopy. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Synthetic Route of 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Angnes, Ricardo A.; Oliveira, Juliana M.; Oliveira, Caio C.; Martins, Nelson C.; Correia, Carlos Roque D. published the artcile< Stereoselective Synthesis of Aryl Cyclopentene Scaffolds by Heck-Matsuda Desymmetrization of 3-Cyclopentenol>, COA of Formula: C13H15F3N2O, the main research area is arylcyclopentenol diastereoselective enantioselective preparation; arylcyclopentanone enantioselective preparation; Heck Matsuda desymmetrization cyclopentenol aryldiazonium salt palladium pyridinyloxazoline catalyst; diastereoselective enantioselective Heck Matsuda reaction aryldiazonium salt cyclopentenol; bromophenyl chlorophenyl cyclopentenol mol crystal structure; Heck reaction; aryldiazonium salts; chiral N,N ligands; desymmetrization; palladium.

In the presence of palladium bis(trifluoroacetate) and nonracemic (trifluoromethyl)pyridinyloxazoline I, aryldiazonium trifluoroborates RN2+ BF4- [R = 4-MeOC6H4, 2-MeOC6H4, 3,4-(MeO)2C6H3, 3,4,5-(MeO)3C6H2, 4-HOC6H4, 2-HOC6H4, Ph, 4-BrC6H4, 4-ClC6H4, 4-O2NC6H4, 3-O2NC6H4, 2-O2NC6H4, 4-F3CC6H4, 3-F3CC6H4, 2-F3CC6H4] underwent enantioselective Heck-Matsuda desymmetrization reactions with 3-cyclopenten-1-ol to give arylcyclopentenols II [R = 4-MeOC6H4, 2-MeOC6H4, 3,4-(MeO)2C6H3, 3,4,5-(MeO)3C6H2, 4-HOC6H4, 2-HOC6H4, Ph, 4-BrC6H4, 4-ClC6H4, 4-O2NC6H4, 3-O2NC6H4, 2-O2NC6H4, 4-F3CC6H4, 3-F3CC6H4, 2-F3CC6H4] in 20-70% yields and in 85-99% ee and (in some cases) nonracemic 3-arylcyclopentenones in 12-27% yields and in 17-93% ee. The hydroxy group of the cyclopentenol reactant acted as a directing group to control the relative stereochem. of the coupling reaction. The structures of II (R = 4-BrC6H4, 4-ClC6H4) were determined by X-ray crystallog.

Chemistry – A European Journal published new progress about Alcohols, unsaturated Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, COA of Formula: C13H15F3N2O.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tunca, Ekrem; Bulbul, Metin; Ilkimen, Halil; Canlidinc, Rukiye Saygili; Yenikaya, Cengiz published the artcile< Investigation of the effects of the proton transfer salts of 2-aminopyridine derivatives with 5-sulfosalicylic acid and their Cu(II) complexes on cancer-related carbonic anhydrases: CA IX and CA XII>, Reference of 21901-29-1, the main research area is cancer sulfosalicylic acid aminopyridine carbonic anhydrase IX XII.

Abstract: Six novel proton transfer compounds (15-20) obtained from 5-sulfosalicylic acid (1) and 2-aminopyridine derivatives [2-amino-3-benzyloxypyridine (2), 2-amino-3-hydroxylpyridine (3), 2-amino-3-methylpyridine (4), 2-amino-3-nitropyridine (5), 2-amino-3-nitro-4-methylpyridine (6) and 2-amino-3-nitro-6-methylpyridine (7)] and their Cu(II) complexes (21-26) along with the Cu(II) complexes of 2-7 (9-14) have been prepared and characterized by spectroscopic techniques. The in vitro inhibition effects of all compounds on CA IX and CA XII isoenzymes as well as on hCA I and hCA II were investigated and the results were compared. The inhibition studies showed that the synthesized compounds are more selective to CA XII isoenzyme. The hydratase IC50 values of the compounds were determined as in the range of 15.61 ± 2.32 uM-99.02 ± 4.99 uM for hCA I, 22.36 ± 0.75 uM-77.03 ± 4.03 uM for hCA II, 23.90 ± 1.67 uM-138.63 ± 5.45 uM for CA IX, and 9.50 ± 1.16 uM-693.15 ± 8.96 uM for CA XII. The inhibition data have been analyzed using one-way anal. of variance for multiple comparisons (p < 0.0001). Chemical Papers published new progress about Enzyme inhibition kinetics. 21901-29-1 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Reference of 21901-29-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tapanyigit, Ozan; Demirkol, Onur; Guler, Ece; Ersatr, Mehmet; Cam, Muhammet Emin; Giray, Elife Sultan published the artcile< Synthesis and investigation of anti-inflammatory and anticonvulsant activities of novel coumarin-diacylated hydrazide derivatives>, Product Details of C7H7NO2, the main research area is coumarin diacylated hydrazide derivative anticonvulsant anti inflammatory.

A number of novel coumarin derivatives synthesized by the reaction of 3-carbonyl chloride coumarin with some substituted aryl acid hydrazides to investigate their anti-inflammatory and anticonvulsant activities. Carrageenan (0.1 mL of 1%, w/v) was injected subplantarly in the right paw of rats to induce an acute model of inflammation. Anti-inflammatory efficacy was evaluated for 5 h at 3 different dosages 5, 10, 25 mg/kg. After that, the changes in the level of paw edema volumes and percentage inhibition of all groups were observed and the most effective coumarin derivative was found as N′-(2-hyroxybenzoyl)-2-oxo-2H-chromene-3-carbohydrazide. In addition, N′-(2-oxo-2H-chromene-3-carbonyl)nicotinohydrazide, (E)-N′-(3-(4-hydroxyphenyl)acryloyl)-2-oxo-2H-chromene-3-carbohydrazide, and N′-(5-amino-2-hydroxybenzoyl)-2-oxo-2H-chromone-3-carbohydrazide showed their anti-inflammatory effects in a dose-dependent manner. On the other hand, pentylenetetrazole (PTZ, 80 mg/kg, i.p.)-induced seizure model was used to investigate the anticonvulsant activities of six newly synthesized coumarin derivatives in mice. Hybrid compound of salicylic acid hydrazide and 3-carbonyl chloride coumarin was found the most promising anticonvulsant agent among all treatment groups according to the onset of seizure and survival rate. Moreover, (E)-N′-cinnamoyl-2-oxo-2H-chromene-3-carbohyrazide and (E)-N′-(3-(4-hyroxyphenyl)acryloyl)-2-oxo-2H-chromene-3-carbohydrazide has potential anticonvulsant efficiency in low doses (30 mg/kg). The anticonvulsant effect of these coumarin derivatives may be through enhanced GABA-mediated inhibition in the brain.

Arabian Journal of Chemistry published new progress about Anti-inflammatory agents. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Product Details of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Schuster, Georg; Lindner, Wolfgang published the artcile< Comparative characterization of hydrophilic interaction liquid chromatography columns by linear solvation energy relationships>, Related Products of 21876-43-7, the main research area is hydrophilic interaction liquid chromatog column linear solvation energy relationship; acid organic hydrophilic interaction LC linear solvation energy relation; base organic hydrophilic interaction LC linear solvation energy relation.

Twenty-two com. available and home-made stationary phases with different surface modifications were compared under hydrophilic interaction liquid chromatog. (HILIC) conditions. The column set comprised neutral, basic, acidic, zwitterionic and mixed surface modifications. Retention data of 68 differently structured test solutes were acquired to generate retention models based on a linear solvation energy relation (LSER) approach. A recently modified solvation parameter model with two addnl. mol. descriptors was evaluated in terms of its universal applicability when electrostatic forces are enabled in addition to predominant partition phenomena. The suggested method could not be confirmed to be a standardized way to characterize HILIC systems when different operating conditions are applied. However, the significant contribution of the recently introduced charge descriptors (D- and D+) on explaining the interactions within HILIC systems was confirmed. The solvation parameter model is a useful tool in column development, to affirm or dismiss the preceding educated guess on how certain immobilized ligands will behave. Acidic modified surfaces (stationary phases) exhibit a very small hydrogen bond acceptor property and are less versatile when it comes to an even distribution of solutes along the retention window. Also, basic and neutral columns are more preferable for HILIC applications and might explain why only a limited variety of strong acidic modified HILIC columns, although found in literature, are available com.

Journal of Chromatography A published new progress about Electrostatic force. 21876-43-7 belongs to class pyridine-derivatives, and the molecular formula is C9H13NO3S, Related Products of 21876-43-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

He, Qiao; Guo, Mingming; Jin, Tony Z.; Arabi, Saifanassour Ali; Liu, Donghong published the artcile< Ultrasound improves the decontamination effect of thyme essential oil nanoemulsions against Escherichia coli O157: H7 on cherry tomatoes>, Electric Literature of 123-03-5, the main research area is cherry tomato Escherichia coli thyme essential oil nanoemulsion decontamination; Antibacterial activity; Cherry tomato; E. coli O157:H7; Thyme essential oil nanoemulsion; Ultrasound.

Development of novel and effective decontamination technologies to ensure the microbiol. safety of fresh produce has gained considerable attention, mainly driven by numerous outbreaks. This work presented the first approach regarding to the application of the previously reported hurdle technologies on the sanitization of artificially contaminated cherry tomatoes. Thyme (Thymus daenensis) essential oil nanoemulsion (TEON, 8.28 nm in diameter with a narrow size distribution) was formulated via ultrasonic nanoemulsification, showing remarkably improved antimicrobial activity against Escherichia coli (E. coli) O157:H7, compared to the coarse emulsion. The antimicrobial effect of ultrasound (US), thyme essential oil nanoemulsion (TEON) and the combination of both treatments was assessed against E. coli O157:H7. The remarkable synergistic effects of the combined treatments were achieved, which decontaminated the E. coli populations by 4.49-6.72 log CFU/g on the surface of cherry tomatoes, and led to a reduction of 4.48-6.94 log CFU/sample of the total inactivation. TEON combined with US were effective in reducing the presence of bacteria in wastewater, which averted the potential detrimental effect of cross-contamination resulted from washing wastewater in fresh produce industry. Moreover, the treatments did not noticeably alter the surface color and firmness of cherry tomatoes. Therefore, ultrasound combined with TEON is a promising and feasible alternative for the reduction of microbiol. contaminants, as well as retaining the quality characteristics of cherry tomatoes.

International Journal of Food Microbiology published new progress about Antimicrobial agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Electric Literature of 123-03-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Attatsi, Isaac Kwaku; Zhu, Weihua; Liang, Xu published the artcile< Noncovalent immobilization of Co(II) porphyrin through axial coordination as an enhanced electrocatalyst on carbon electrodes for oxygen reduction and evolution>, Category: pyridine-derivatives, the main research area is cobalt tetraphenylporphyrin carbon nanotube glassy carbon oxygen reduction evolution.

Catalysis of fuel-producing reactions can be transferred from homogeneous solution to a surface via attachment of the mol. catalyst. A pyrene-pyridine hybrid (Py-Py) was used as an axial ligand to bridge Co(II)tetraphenylporphyrin which was finally immobilized on carbon nanotubes via noncovalent interactions and further deposited on glassy carbon. This noncovalent immobilization of Co(II)porphyrin through axial coordination provides significantly enhanced electrochem. catalyzed oxygen reduction and oxygen evolution, illustrating a new insight into understanding surface catalysis.

New Journal of Chemistry published new progress about Bifunctional catalysts. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rashed, Nurnobi Md.; Masuda, Koichiro; Ichitsuka, Tomohiro; Koumura, Nagatoshi; Sato, Kazuhiko; Kobayashi, Shu published the artcile< Zirconium Oxide-Catalyzed Direct Amidation of Unactivated Esters under Continuous-Flow Conditions>, Product Details of C7H7NO2, the main research area is amine ester zirconium catalyst amidation green chem; amide preparation.

A sustainable and environmentally benign direct amidation reaction of unactivated esters with amines was developed in a continuous-flow system. A com. available amorphous zirconium oxide was found to be an efficient catalyst for this reaction. While the typical amidation of esters with amines required a stoichiometric amount of a promoter or metal activator, the present continuous-flow method enabled the direct amidation reaction under additive-free conditions with an extensive diversity towards various functional groups. High yields of the products were obtained with a nearly equimolar proportion of starting materials to reduce byproduct formation, which rendered this process applicable for use in a sequential-flow system.

Advanced Synthesis & Catalysis published new progress about Amidation. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Product Details of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sun, Yi; Hu, Xueyan; Guo, Du; Shi, Chao; Zhang, Chunling; Peng, Xiaoli; Yang, Hua; Xia, Xiaodong published the artcile< Disinfectant Resistance Profiles and Biofilm Formation Capacity of Escherichia coli Isolated from Retail Chicken>, Formula: C21H38ClN, the main research area is resistance biofilm formation Escherichia chicken; biofilm formation capacity; disinfectant resistance; disinfectant-resistant genes.

Disinfectant resistance and biofilm formation capacity are two important characteristics that contribute to the persistence of microorganisms in food processing environments and contamination of food products. This study investigated the susceptibility of 510 Escherichia coli isolates against 5 disinfectants and the prevalence of 10 disinfectant-resistant genes in these isolates. The biofilm formation capacity of 194 isolates was determined, and the correlation between disinfectant resistance and biofilm formation was analyzed. The minimal inhibitory concentrations (MICs) of cetyltrimethylammonium bromide (CTAB), benzalkonium chloride (BC), cetylpyridinium chloride, and chlorhexidine (CHX) against isolates were 32-512, 16-256, 32-256, and 2-32 mg/L, resp. The MICs of triclosan against 88.43% of isolates were 8-1,024 mg/L, while the MICs for the rest of isolates exceed 2,048 mg/L. The presence of ydgE, ydgF, and qacF genes was significantly correlated with the CHX resistance of E. coli isolates, while the presence of qacF and qacEΔ1 genes was significantly correlated with CTAB and BC resistance, resp. The biofilm formation capacity (adjusted optical d. value) was pos. correlated with BC resistance (r = 0.201, p < 0.01) and showed no correlation with other disinfectants. The presence of sugE(p) was pos. correlated with biofilm formation, while four genes were neg. correlated with biofilm formation. This study provides useful data on disinfectant resistance and biofilm formation capacity of E. coli contaminating poultry products, which could be helpful in guiding proper disinfectant usage and establishing effective biofilm eradication strategy in food industry. Microbial Drug Resistance (New Rochelle, NY, United States) published new progress about Biofilms (microbial). 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Shahsavari, Hamid R.; Babadi Aghakhanpour, Reza; Biglari, Abbas; Niazi, Maryam; Mastrorilli, Piero; Todisco, Stefano; Gallo, Vito; Lalinde, Elena; Moreno, M. Teresa; Gimenez, Nora; Halvagar, Mohammad Reza published the artcile< C(sp2)-C(sp2) Reductive Elimination from a Diarylplatinum(II) Complex Induced by a S-S Bond Oxidative Addition at Room Temperature>, Product Details of C10H8N2S2, the main research area is arylplatinum benzothiazolethiolate pyridinethiolate preparation crystal structure; crystal structure diarylplatinum benzothiazolethiolate pyridinethiolate dinuclear platinum lantern complex; mol structure diarylplatinum benzothiazolethiolate pyridinethiolate dinuclear platinum lantern complex; dinuclear platinum lantern complex preparation crystal structure; diarylplatinum complex oxidative addition benzothiazolethiolate pyridinethiolate.

The synthesis and characterization of three six-coordinated Pt(IV) complexes [Pt(Ar)2(S[symbol omitted]N)2] (S[symbol omitted]N = Sbt, benzothiazole-2-thiolate, Ar = p-MeC6H4 (1a), C6F5 (1b); S[symbol omitted]N = Spy, 2-pyridinethiolate, Ar = p-MeC6H4 (1c)) is described. Of these, 1a undergoes, at room temperature and within 18 h, a remarkable C-C reductive elimination process between the aryl ligands to give, as the final products, the stable binuclear lantern complex [Pt2(Sbt)4] (2a) and 4,4′-dimethylbiphenyl. Differently from 1a, solutions of 1b,c are indefinetively stable up to 60° and do not undergo reductive elimination. Complexes 1a-c and 2a were characterized by IR and NMR spectroscopy, high-resolution mass spectrometry, and single-crystal x-ray crystallog. (1b,c and 2a). 1H-19F HOESY experiments on 1b demonstrated the presence of a through-space coupling between proximal F and H atoms of the mol. that are separated by six bonds but are in close spatial proximity.

Organometallics published new progress about Crystal structure. 2127-03-9 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2S2, Product Details of C10H8N2S2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem