Month: October 2022

The author of 《In situ polymerization of magnetic graphene oxide-diaminopyridine composite for effective adsorption of Pb(II) and application in battery industry wastewater treatment》 were Wang, Zongwu; Wu, Qing; Zhang, Jing; Zhang, Huan; Feng, Jinglan; Dong, Shuying; Sun, Jianhui. And the article was published in Environmental Science and Pollution Research in 2019. Recommanded Product: 2,6-Diaminopyridine The author mentioned the following in the article:

The efficient removal of heavy metals from aqueous environment is imperative and challenging. A novel ternary composite constructed of diaminopyridine polymers, graphene oxide, and ferrite magnetic nanoparticles was designed by a facile in situ polymerization strategy for the removal of Pb(II) from aqueous solution Detailed characterization of morphol., chem., and magnetic properties was employed systematically to confirm the formation of the composite material. Batch adsorption experiment studies suggested that the composite was an excellent adsorbent for Pb(II) which was easily collected after use via exposure to an external magnetic field for 30 s. The effects of different parameters such as solution pH, adsorbent dosage, contact time, initial Pb(II) concentration, temperature, and co-existing ions were examined The maximum adsorption capacity at pH = 5 was estimated to be 387.2 mg g-1 at 298 K by the Langmuir isotherm model, accompanied by favorable adsorption recyclability according to the investigation of regeneration experiments Thermodn. studies revealed that the Pb(II) adsorption via our ternary composite was endothermic and spontaneous. The corresponding removal performance for effluent containing Pb(II) from the battery industry was successfully examined The present results indicated that our designed adsorbent is beneficial to the practical Pb(II) removal in wastewater purification In the experimental materials used by the author, we found 2,6-Diaminopyridine(cas: 141-86-6Recommanded Product: 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Recommanded Product: 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《A Single-Crystal Open-Capsule Metal-Organic Framework》 were Wei, Yong-Sheng; Zhang, Mei; Kitta, Mitsunori; Liu, Zheng; Horike, Satoshi; Xu, Qiang. And the article was published in Journal of the American Chemical Society in 2019. Application In Synthesis of 4-Acetylpyridine The author mentioned the following in the article:

Micro-/nanocapsules have received substantial attention due to various potential applications for storage, catalysis, and drug delivery. However, their conventional enclosed non-/polycrystalline walls pose huge obstacles for rapid loading and mass diffusion. Here, the authors present a new single-crystal capsular-MOF with openings on the wall, which is carefully designed at the mol. level and constructed from a crystal-structure transformation. This rare open-capsule MOF can easily load the largest amounts of S and I among known MOFs. Derived from capsular-MOF and melamine through pyrolysis-phosphidation, the authors fabricated a N-doped capsular C-based framework with Fe-Ni phosphide nanoparticles immobilized on capsular carbons interconnected by plentiful carbon nanotubes. Benefiting from synergistic effects between the C framework and highly surface-exposed phosphide sites, the material exhibits efficient multifunctional electrocatalysis for O evolution, H evolution, and O reduction, achieving well-qualified assemblies of an overall H2O splitting (low potential of 1.59 V at 10 mA cm-2) and a rechargeable Zn-air battery (high peak power d. of 250 mW cm-2 and excellent stability for 500 h), which afford remarkably practical prospects over previously known electrocatalysts. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9Application In Synthesis of 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Application In Synthesis of 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Structure characterization and antitumor activity of palladium pseudo halide complexes with 4-acetylpyridine》 were El-bendary, Mohamed M.; Arshad, Muhammad N.; Asiri, Abdullah M.. And the article was published in Journal of Coordination Chemistry in 2019. Related Products of 1122-54-9 The author mentioned the following in the article:

The addition of an aqueous solution of palladium chloride to an aqueous acetonitrile solution of 4-acetylpyridine (4-Acpy) and KSCN or NaN3 produces new complexes, [Pd(SCN)2(4-Acpy)2] (1) and [Pd(N3)2(4-Acpy)2] (2), at ambient conditions. Complexes 1 and 2 were characterized by elemental anal., FTIR, and UV-Visible spectra. The structures of 1 and 2 were determined by single crystal x-ray diffraction. The coordination geometry around the palladium center is distorted square planar in 1 and 2 as the palladium is coordinated with two 4-acetylpyridine and two thiocyanates in 1 or two azide groups in 2. The discrete units of 1 and 2 extend along the a-axis creating a 1 D-chain via noncovalent hydrogen bonds. The extensive noncovalent hydrogen bonds extend the structure of 1 and 2 to 3-dimensional-networks. Using MTT assay, the cytotoxic activities of 1 and 2 were screened against two cancer cell lines, HePG-2 (liver cancer) and MCF-7 (breast cancer). The MTT assay revealed that the cytotoxic activity of 1 is stronger than 2 for HePG-2 and MCF-7. Antioxidant and anti-hemolytic activities of 1 and 2 were examined Also, the luminescence spectra in the solid state of 1 and 2 are discussed. In the experiment, the researchers used 4-Acetylpyridine(cas: 1122-54-9Related Products of 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Related Products of 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Graphene Oxide as a Carbocatalyst for Sustainable ipso-Hydroxylation of Arylboronic Acids: A Simple and Straightforward Strategy To Access Phenols》 were Karthik, Murugan; Suresh, Palaniswamy. And the article was published in ACS Sustainable Chemistry & Engineering in 2019. COA of Formula: C5H6BNO2 The author mentioned the following in the article:

A metal-free and straightforward protocol for the synthesis of phenols from aryl and heteroaryl boronic acids has been demonstrated using graphene oxide as a carbocatalyst. This sustainable ipso-hydroxylation takes place under mild conditions using aqueous H2O2 as an oxidant in a water medium in a short time under organocatalytic and base-free conditions. The control experiments reveal that the presence of carboxyl groups promotes ipso-hydroxylation. The developed methodol. offers GO as a benign solid-acid catalyst with good sustainability which can be reused several times without significant loss in its catalytic activities; this was proven by the Fourier transform IR and powder X-ray diffraction studies of the reused catalyst. In the experiment, the researchers used Pyridin-3-ylboronic acid(cas: 1692-25-7COA of Formula: C5H6BNO2)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. COA of Formula: C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Non-chelating p-phenylidene-linked bis-imidazoline analogs of known influenza virus endonuclease inhibitors: Synthesis and anti-influenza activity》 were Dar’in, Dmitry; Zarubaev, Vladimir; Galochkina, Anastasia; Gureev, Maxim; Krasavin, Mikhail. And the article was published in European Journal of Medicinal Chemistry in 2019. Electric Literature of C5H6BNO2 The author mentioned the following in the article:

A novel chemotype topol. similar to known influenza virus PA endonuclease inhibitors was designed. It was aimed to reproduce the extended topol. of the known metal-chelating ligands with a p-phenylidene-linked bis-imidazoline scaffold. It was envisioned that aromatic groups introduced to this scaffolds via metal-catalyzed N-arylation (Buchwald-Hartwig or Chan-Evans-Lam) would contribute to lipophilic binding to the target and one of the imidazoline nitrogen atoms would ensure non-chelating coordination to the prosthetic divalent metal ion. The compounds displayed appreciable anti-influenza activity in vitro and substantial concentration window from the general cytotoxicity range. Docking anal. of low-energy poses of the most active compound (as well as their comparison to the binding of an inactive compound) revealed that these compounds reproduced similar binding components to a known PA endonuclease inhibitor and displayed similar binding pose and desired monodentate metal coordination, as was initially envisioned. These findings warrant further study of the mechanism of action of the newly discovered series. In addition to this study using 2-Pyridinylboronic acid, there are many other studies that have used 2-Pyridinylboronic acid(cas: 197958-29-5Electric Literature of C5H6BNO2) was used in this study.

2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Electric Literature of C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Asymmetric remote C-H borylation of aliphatic amides and esters with a modular iridium catalyst》 was published in Science (Washington, DC, United States) in 2020. These research results belong to Reyes, Ronald L.; Sato, Miyu; Iwai, Tomohiro; Suzuki, Kimichi; Maeda, Satoshi; Sawamura, Masaya. Electric Literature of C5H6BNO2 The article mentions the following:

Site selectivity and stereocontrol remain major challenges in C-H bond functionalization chem., especially in linear aliphatic saturated hydrocarbon scaffolds. We report the highly enantioselective and site-selective catalytic borylation of remote C(sp3)-H bonds γ to the carbonyl group in aliphatic secondary and tertiary amides and esters. A chiral C-H activation catalyst was modularly assembled from an iridium center, a chiral monophosphite ligand, an achiral urea-pyridine receptor ligand, and pinacolatoboryl groups. Quantum chem. calculations support an enzyme-like structural cavity formed by the catalyst components, which bind the substrate through multiple noncovalent interactions. Versatile synthetic utility of the enantioenriched γ-borylcarboxylic acid derivatives was demonstrated. In the experimental materials used by the author, we found Pyridin-3-ylboronic acid(cas: 1692-25-7Electric Literature of C5H6BNO2)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Electric Literature of C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Aryl-Nickel-Catalyzed Benzylic Dehydrogenation of Electron-Deficient Heteroarenes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Zhang, Pengpeng; Huang, David; Newhouse, Timothy R.. Recommanded Product: 2-Bromo-5-methylpyridine The article mentions the following:

This manuscript describes the first practical benzylic dehydrogenation of electron-deficient heteroarenes, including pyridines, pyrazines, pyrimidines, pyridazines, and triazines. This transformation allows for the efficient benzylic oxidation of heteroarenes to afford heterocyclic styrenes by the action of nickel catalysis paired with an unconventional bromothiophene oxidant. The experimental part of the paper was very detailed, including the reaction process of 2-Bromo-5-methylpyridine(cas: 3510-66-5Recommanded Product: 2-Bromo-5-methylpyridine)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Recommanded Product: 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Huang, Zhiliang; Guan, Renpeng; Shanmugam, Muralidharan; Bennett, Elliot L.; Robertson, Craig M.; Brookfield, Adam; McInnes, Eric J. L.; Xiao, Jianliang published their research in Journal of the American Chemical Society in 2021. The article was titled 《Oxidative Cleavage of Alkenes by O2 with a Non-Heme Manganese Catalyst》.Synthetic Route of C7H7NO The article contains the following contents:

The oxidative cleavage of C=C double bonds with mol. oxygen to produce carbonyl compounds is an important transformation in chem. and pharmaceutical synthesis. In nature, enzymes containing the first-row transition metals, particularly heme and non-heme iron-dependent enzymes, readily activate O2 and oxidatively cleave C=C bonds with exquisite precision under ambient conditions. The reaction remains challenging for synthetic chemists, however. There are only a small number of known synthetic metal catalysts that allow for the oxidative cleavage of alkenes at an atm. pressure of O2, with very few known to catalyze the cleavage of nonactivated alkenes. In this work, we describe a light-driven, Mn-catalyzed protocol for the selective oxidation of alkenes to carbonyls under 1 atm of O2. For the first time, aromatic as well as various nonactivated aliphatic alkenes could be oxidized to afford ketones and aldehydes under clean, mild conditions with a first row, biorelevant metal catalyst. Moreover, the protocol shows a very good functional group tolerance. Mechanistic investigation suggests that Mn-oxo species, including an asym., mixed-valent bis(μ-oxo)-Mn(III,IV) complex, are involved in the oxidation, and the solvent methanol participates in O2 activation that leads to the formation of the oxo species. In the part of experimental materials, we found many familiar compounds, such as 4-Acetylpyridine(cas: 1122-54-9Synthetic Route of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Synthetic Route of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wagener, Tobias; Lueckemeier, Lukas; Daniliuc, Constantin G.; Glorius, Frank published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Interrupted pyridine hydrogenation: Asymmetric synthesis of δ-lactams》.Name: 2-Bromo-5-methylpyridine The article contains the following contents:

Metal-catalyzed hydrogenation is an effective method to transform readily available arenes into saturated motifs, however, current hydrogenation strategies are limited to the formation of C-H and N-H bonds. The stepwise addition of hydrogen yields reactive unsaturated intermediates that are rapidly reduced. In contrast, the interruption of complete hydrogenation by further functionalization of unsaturated intermediates offers great potential for increasing chem. complexity in a single reaction step. Overcoming the tenet of full reduction in arene hydrogenation has been seldom demonstrated. In this work the authors report the synthesis of sought-after, enantioenriched δ-lactams from oxazolidinone-substituted pyridines and water by an interrupted hydrogenation mechanism. The experimental process involved the reaction of 2-Bromo-5-methylpyridine(cas: 3510-66-5Name: 2-Bromo-5-methylpyridine)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Name: 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rajesh, Sarigama; Zhai, Jiali; Drummond, Calum J.; Tran, Nhiem published an article in 2021. The article was titled 《Synthetic ionizable aminolipids induce a pH dependent inverse hexagonal to bicontinuous cubic lyotropic liquid crystalline phase transition in monoolein nanoparticles》, and you may find the article in Journal of Colloid and Interface Science.Recommanded Product: 2-(2-Hydroxyethyl)pyridine The information in the text is summarized as follows:

A prospective class of materials for drug delivery is lyotropic liquid crystalline (LLC) nanoparticles, such as cubosomes and hexosomes. Efforts are being made to generate a pH dependent system, which exhibits slow release hexosomes (H2) at physiol. pH and relatively fast release cubosomes (Q2) at acidic disease sites such as in various cancers and bacterial infection (pH ∼ 5.5-6.5). Herein, we report the synthesis of nine ionizable aminolipids, which were doped into monoolein (MO) lipid nanoparticles. Using high throughput formulation and synchrotron small angle X-ray scattering (SAXS), the effects of aminolipid structure and concentration on the mesophase of MO nanoparticles at various pHs were determined As the pH changed from neutral to acidic, mesophases, could be formed in an order L2 (inverse micelles) → H2 → Q2. Specifically, systems with heterocyclic oleates exhibited the H2 to Q2 transition at pH 5.5-6.5. Furthermore, the phase transition pH could be fine-tuned by incorporating two aminolipids into the nanoparticles. Nanoparticles with a pH dependent phase transition as described in this study may be useful as drug delivery carriers for the treatment of cancers and certain bacterial infection. In the experiment, the researchers used many compounds, for example, 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Recommanded Product: 2-(2-Hydroxyethyl)pyridine)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 2-(2-Hydroxyethyl)pyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem