Month: October 2022

Zhang, Penglin; Zhang, Min; Ji, Yuqi; Xing, Mimi; Zhao, Qian; Zhang, Chun published the artcile< Nickel-Catalyzed Highly Selective Hydroalkenylation of Alkenyl Boronic Esters to Access Allyl Boron>, Application of C13H15F3N2O, the main research area is nickel catalyzed hydroalkenylation alkenyl boronic ester cyclohexenyl triflate; boronate allyl preparation oxidation; allyl alc preparation.

Allyl B derivatives are valuable building blocks in the synthesis of natural products and bioactive mols. Herein, a practical strategy of Ni-catalyzed highly selective hydroalkenylation of alkenyl boronic esters was developed. Under the mild reaction conditions, a variety of allyl boronic esters were accessed with excellent chemo- and regioselectivity. The mechanism of this transformation was illustrated by control experiments and kinetic studies.

Organic Letters published new progress about Alkenylation catalysts (Ni complexes). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Application of C13H15F3N2O.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jia, Jidong; Zhang, Xueru; Wang, Yuxiao; Shi, Yufang; Sun, Jinyu; Yang, Junyi; Song, Yinglin published the artcile< Enhanced Two-Photon Absorption of Cross-Conjugated Chalcone Derivatives: Modulation of the Effective π-Conjugated Structure>, Recommanded Product: 1-(Pyridin-3-yl)ethanone, the main research area is enhanced photon absorption cross conjugated chalcone derivative modulation effective.

Three cross-conjugated chalcone derivatives T3CT, T3CP2, and T3CP3 were designed and synthesized to develop excellent organic nonlinear optical (NLO) materials. In a Z-scan experiment, all compounds show good NLO absorption characteristics in the visible to near-IR region. The photophys. mechanism is confirmed to be two-photon absorption (TPA)-induced excited-state absorption (ESA). Intramol. charge transfer (ICT) observed in transient absorption spectra (TAS) significantly affects mol. NLO properties. We define the π-conjugated system that dominates the electron transition process in the cross-conjugated structure as the effective π-conjugated structure. Electron transition anal. shows a sufficiently strong ICT can effectively expand the effective π-conjugated structure in these cross-conjugated structures. The TPA cross sections of these compounds at 650 and 750 nm are only in the range of 17-97 GM. However, we achieve a significant enhancement of the TPA cross section at 580 nm (1737-2027 GM) by extending the effective π-conjugated structure. Excited by 580 nm femtosecond laser pulses, all compounds exhibit excellent OL performance and the min. OL threshold is 4.71 x 10-3 J/cm2. The results show that these cross-conjugated chalcone derivatives have promising applications in OL, and their NLO performance can be effectively improved by modulating the effective π-conjugated structure.

Journal of Physical Chemistry A published new progress about Conjugation (bond). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Recommanded Product: 1-(Pyridin-3-yl)ethanone.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Smolyar, N. N.; Yutilov, Yu. M. published the artcile< Reduction of 2-amino-3- and -5-nitropyridine derivatives with hydrazine hydrate>, Related Products of 21901-29-1, the main research area is nitropyridinamine reduction hydrazine hydrate; pyridinamine preparation.

The reactions of 3- and 5-nitro-2-pyridinamine with N2H4.H2O resulted in elimination of the NH2 group and reduction of the NO2 group with formation of 3-pyridinamine. A probable reaction mechanism involves addition of N2H4.H2O to the N-C(2) bond, followed by elimination of NH3 and reduction of the NO2 group to NH2. 4- And 5-methyl-3-nitro-2-pyridinamine reacted with N2H4.H2O in a similar way.

Russian Journal of Organic Chemistry published new progress about Aromatic amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 21901-29-1 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Related Products of 21901-29-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tkachuk, Viktor M.; Lukianov, Oleh O.; Vovk, Mykhailo V.; Gillaizeau, Isabelle; Sukach, Volodymyr A. published the artcile< Chan-Evans-Lam N1-(het)arylation and N1-alkenylation of 4-fluoroalkylpyrimidin-2(1H)-ones>, Related Products of 329214-79-1, the main research area is substituted pyrimidone preparation; fluoroalkylpyrimidinone boronic acid arylation alkenylation copper catalyst; alkenylboronic acid pinacol ester fluoroalkylpyrimidinone arylation alkenylation copper catalyst; Chan–Evans–Lam reaction; C–N cross-coupling; boronic acids; fluoroalkyl group; pyrimidin-2(1Н)-ones.

The Chan-Evans-Lam reaction of 1-unsubstituted 4-fluoroalkylpyrimidin-2(1H)-ones with arylboronic acids was reported as a facile synthetic route to hitherto unavailable N1-(het)aryl and N1-alkenyl derivatives of the corresponding pyrimidines I [R = CH=CH2, Ph, 3-thienyl, etc.; R1 = CHF2, CF3, C2F5, CClF2; R2 = H, Br, CO2Me]. An efficient C-N bond-forming process was also observed by using boronic acid pinacol esters as coupling partners in the presence of Cu(II) acetate and boric acid. The 4-fluoroalkyl group on the pyrimidine ring significantly assists in the formation of the target N1-substituted products, in contrast to the 4-Me and 4-unsubstituted substrates which did not undergo N1-arylation under similar reaction conditions.

Beilstein Journal of Organic Chemistry published new progress about Alkenylation. 329214-79-1 belongs to class pyridine-derivatives, and the molecular formula is C11H16BNO2, Related Products of 329214-79-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Huo, Shuaicong; Kong, Siqi; Zeng, Guang; Feng, Qi; Hao, Zhiqiang; Han, Zhangang; Lin, Jin; Lu, Guo-Liang published the artcile< Efficient access to quinolines and quinazolines by ruthenium complexes catalyzed acceptorless dehydrogenative coupling of 2-aminoarylmethanols with ketones and nitriles>, Product Details of C7H7NO, the main research area is quinoline preparation; quinazoline preparation; ketone aminoarylmethanol dehydrogenative coupling reaction ruthenium catalyst; nitrile aminoarylmethanol dehydrogenative coupling reaction ruthenium catalyst.

Treatment of N,N,O-tridentate pyrazolyl-pyridinyl-alc. ligands, I (R = H, Me; R1 = H, Me, Ph; R2 = Me, Ph) with RuCl3·xH2O in refluxing EtOH afforded the corresponding Ru(III) complexes II, as chlorides, which were well characterized by IR, HR-MS and X-ray single crystal structural determination These Ru complexes II showed similarly high catalytic performance for both dehydrogenative couplings of 2-aminoarylmethanols [2-NH2-3-R3-5-R4C6H2CH2OH (R3 = H, Me, Br; R4 = H, F, Cl, Br) and 3-amino-3-phenyl-1-propanol] with ketones [R5C(O)CH3 (R5 = Ph, pyridin-3-yl, thiophen-2-yl, etc.), cycloheptanone and 1,2,3,4-tetrahydronaphthalen-1-one] and nitriles R6CN (R6 = Ph, 3-bromophenyl, thien-2-yl, etc.), giving the quinolines III, IV, V and 2,6-diphenylpyridine and quinazolines VI in good to excellent yields. This protocol provides an atom-economical and sustainable route to access various structurally important quinolines III, IV, V and 2,6-diphenylpyridine and quinazolines VI derivatives by using phosphine-free ligand based Ru catalysts II.

Molecular Catalysis published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Product Details of C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N. published the artcile< Synthesis of some fluorine-containing pyridinealdoximes of potential use for the treatment of organophosphorus nerve-agent poisoning>, Name: 2-Amino-3-nitro-6-picoline, the main research area is fluorinated pyridinealdoxime preparation treatment organophosphorus nerve agent poisoning; sarin poisoning fluorinated pyridinealdoxime preparation treatment.

Fluoroheterocyclic aldoximes were screened as therapeutic agents for the treatment of anticholinesterase poisoning. 2-Fluoropyridine-3- and -6-aldoxime and 3-fluoropyridine-2- and -4-aldoxime were synthesized. Attempts to obtain 3,5,6-trifluoropyridine-2,4-bis(aldoxime) and -2-aldoxime, however, proved unsuccessful. Pentafluorobenzaldoxime was prepared by oximation of pentafluorobenzaldehyde. Acid dissociation constants (pKa) and second-order rate constants (kox-) of the fluorinated pyridinealdoximes towards sarin were measured. 2,3,5,6-Tetrafluoropyridine-4-aldoxime had the best profile: its kox- approached that of the therapeutic oxime P2S (310 vs. 120 l mol-1 min-1), but its higher pKa (9.1 vs. 7.8) fell short of the target figure of 8 required for reactivation of inhibited acetylcholinesterase in vivo. N-alkylation of the fluorinated pyridine-aldoximes may reduce their pKa nearer to 8 and enhance their therapeutic potential.

Journal of Fluorine Chemistry published new progress about Antidotes. 21901-29-1 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, Name: 2-Amino-3-nitro-6-picoline.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cao, Bing-Jun; Li, Ran; Huang, Xi-He published the artcile< Synthesis, structure and photophysical properties of two tetranuclear copper(I) iodide complexes based on acetylpyridine and diphosphine mixed ligands>, Application of C7H7NO, the main research area is copper iodide complex acetylpyridine diphosphine ligand structure photophys property; TADF; acetylpyridine; bis(diphenyphosphanyl)propane; cluster; copper(I) iodide; crystal structure; photoluminescence; tetramer; thermally activated delayed fluorescence.

Two copper(I) iodide tetramers, namely, [μ2-1,3-bis(diphenylphosphanyl)propane-κ2P:P′]di-μ3-iodido-di-μ2-iodido-[1-(pyridin-3-yl)ethan-1-one-κN]tetracopper(I) dichloromethane disolvate, [Cu4I4(C6H7NO)2(C27H26P2)2]·2CH2Cl2 (CuL3), and [μ2-1,3-bis(diphenylphosphanyl)propane-κ2P:P′]di-μ3-iodido-di-μ2-iodido-[1-(pyridin-4-yl)ethan-1-one-κN]tetracopper(I), [Cu4I4(C6H7NO)2(C27H26P2)2] (CuL4), have been synthesized from reactions of CuI, 1,3-bis(diphenylphosphanyl)propane (dppp) and 3- or 4-acetylpyridine (3/4-acepy). The complexes were characterized by elemental anal., IR spectroscopy, single-crystal X-ray diffraction (XRD), powder XRD and photoluminescence spectroscopy. Both complexes possess a stair-step [Cu4I4] cluster structure with a crystallog. inversion center located in the middle of a Cu2I2 ring (Z′ = 1/2). The dppp ligands each adopt a bidentate coordination mode that bridges two CuI centers on one side of the [Cu4I4] cluster and the acepy ligands act as terminal ligands. The solid-state samples of similar complexes show highly efficiency thermally activated delayed fluorescence (TADF) at room temperature At ambient temperature, both CuL3 and CuL4 exhibit photoluminescence, with a maximum emission in the region 560-580 nm and with short emissive decay times, but only phosphorescence was observed at 77 K. The narrow gaps between the higher lying singlet state and the triplet state, ΔE(S1 – T1), also confirm the presence of TADF. Structure anal. and consideration of photoluminescence indicates that the position of the acetyl group on the heterocyclic ligand has an obvious influence on the structural arrangement, on intermol. interactions and on the observed photophys. properties.

Acta Crystallographica, Section C: Structural Chemistry published new progress about Absorption spectra. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Application of C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yang, Cheng; Xie, Hao published the artcile< Multiple fluorescence response behaviours to proteins/bacteria and selective antibacterial activity of cetylpyridinium chloride (CPC)-based cationic carbon dots>, Formula: C21H38ClN, the main research area is fluorescence cetylpyridinium chloride cationic carbon dot.

Direct interaction between carbon dots (CDs) and biomols. leads to changes in the chem. and phys. status as well as properties of CDs, which can have various biol. and biomedical applications. In this work, the surface of CDs was modified with cetylpyridinium chloride (CPC) to facilitate interactions between CDs and biomols. Multiple fluorescence response behaviors of CPC-based CDs were observed towards several proteins (bovine serum albumin, lysozyme, protamine, and Hb) and bacterial cells (Escherichia coli and Staphylococcus aureus). Electrostatic attraction and hydrogen bonding were involved in inducing aggregation of CDs and fluorence enhancement. An inner filter effect might also occur to reduce fluorescence of CDs when interacting with proteins. Selective antibacterial activity of CPC-based CDs was observed towards Gram pos. bacterium Staphylococcus aureus. This work provides potential to develop CD-based techniques for detecting and visualizing proteins/bacteria as well as selective antibacterial agents towards Gram-pos. bacteria.

RSC Advances published new progress about Antibacterial agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Schwarze, Benedikt; Sobottka, Sebastian; Schiewe, Robert; Sarkar, Biprajit; Hey-Hawkins, Evamarie published the artcile< Spectroscopic and Electronic Properties of Molybdacarborane Complexes with Non-innocently Acting Ligands>, Formula: C10H8N2, the main research area is molybdacarborane containing bipyridine phenanthroline noninnocent ligand preparation electrochem; crystal structure molybdacarborane containing bipyridine phenanthroline noninnocent ligand; mol structure molybdacarborane containing bipyridine phenanthroline noninnocent ligand; Raman spectroscopy; carborane; density functional theory calculations; molybdacarborane; spectroelectrochemistry.

The molybdacarboranes [3-{L-κ2N,N}-3-(CO)2-closo-3,1,2-MoC2B9H11] (L = 2,2′-bipyridine (2,2′-bpy, 1a) or 1,10-phenanthroline (1,10-phen, 1b)) incorporating known potentially noninnocent ligands (CO, 2,2′-bpy, 1,10-phen) and the nonspectator nido-carborane ([η5-C2B9H11]2-) ligand were prepared and fully characterized. High-resolution mass spectrometry, single-crystal x-ray diffraction methods, spectroscopy (IR, (resonance) Raman, NMR), cyclic voltammetry and spectroelectrochem. (electrochem. properties) were supported by theor. studies of the electronic structure (DFT, CAS-SCF, TD-DFT).

Chemistry – A European Journal published new progress about Carboranes Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), SPN (Synthetic Preparation), PROC (Process), PREP (Preparation) (molybdacarboranes containing N,N-donor ligands). 366-18-7 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Formula: C10H8N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Wenbin; Sidhik, Siraj; Traore, Boubacar; Asadpour, Reza; Hou, Jin; Zhang, Hao; Fehr, Austin; Essman, Joseph; Wang, Yafei; Hoffman, Justin M.; Spanopoulos, Ioannis; Crochet, Jared J.; Tsai, Esther; Strzalka, Joseph; Katan, Claudine; Alam, Muhammad A.; Kanatzidis, Mercouri G.; Even, Jacky; Blancon, Jean-Christophe; Mohite, Aditya D. published the artcile< Light-activated interlayer contraction in two-dimensional perovskites for high-efficiency solar cells>, Name: Pyridin-4-ylmethanamine, the main research area is light activated interlayer contraction 2D perovskite solar cell.

Abstract: Understanding and tailoring the phys. behavior of halide perovskites under practical environments is critical for designing efficient and durable optoelectronic devices. Here, we report that continuous light illumination leads to >1% contraction in the out-of-plane direction in two-dimensional hybrid perovskites, which is reversible and strongly dependent on the specific superlattice packing. XPS measurements show that constant light illumination results in the accumulation of pos. charges in the terminal iodine atoms, thereby enhancing the bonding character of inter-slab I-I interactions across the organic barrier and activating out-of-plane contraction. Correlated charge transport, structural and photovoltaic measurements confirm that the onset of the light-induced contraction is synchronized to a threefold increase in carrier mobility and conductivity, which is consistent with an increase in the electronic band dispersion predicted by first-principles calculations Flux-dependent space-charge-limited current measurement reveals that light-induced interlayer contraction activates interlayer charge transport. The enhanced charge transport boosts the photovoltaic efficiency of two-dimensional perovskite solar cells up to 18.3% by increasing the device′s fill factor and open-circuit voltage.

Nature Nanotechnology published new progress about Band gap. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Name: Pyridin-4-ylmethanamine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem