Month: October 2022

The author of 《Construction of Nitrogen-containing Polycyclic Aromatic Compounds by Intramolecular Oxidative C-H/C-H Coupling of Bis(9H-carbazol-9-yl)benzenes and Their Properties》 were Taniguchi, Taisei; Itai, Yuhei; Nishii, Yuji; Tohnai, Norimitsu; Miura, Masahiro. And the article was published in Chemistry Letters in 2019. Category: pyridine-derivatives The author mentioned the following in the article:

Treatment of 1,3- and 1,4-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)benzenes with an oxidizing system of Pd(II)/Ag(I) has been found to induce double intramol. C-H/C-H coupling to give the corresponding highly π-extended polycyclic compds I (X = CH, N), II and III. In contrast, a singly cyclized product IV in a different manner has been isolated from the reaction of 1,2-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)benzene. Cardinal optoelectronic properties of the products have also been estimated2,6-Dibromopyridine(cas: 626-05-1Category: pyridine-derivatives) was used in this study.

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Decarboxylative Hydroalkylation of Alkynes via Dual Copper-Photoredox Catalysis》 was published in ACS Catalysis in 2020. These research results belong to Mastandrea, Marco M.; Canellas, Santiago; Caldentey, Xisco; Pericas, Miquel A.. Recommanded Product: 2510-22-7 The article mentions the following:

A photoredox strategy for the synthesis of a wide range of allylic amines and ethers from carboxylic acids and alkynes has been developed. This approach relies on the perturbation of the ground-state electronic properties of terminal alkynes through the formation and photoexcitation of copper acetylide intermediates. This process takes place through cooperative copper and organic photoredox catalysis and can be carried out in a stereodivergent manner. Thus, a systematic multivariate HTE screening spotlighted that a switch in the stereochem. outcome can be provoked by choosing an appropriate combination of ligand and base. The developed methodol. has been applied to the stereoselective coupling of primary, secondary, and tertiary alkyl radicals with (hetero)aromatic terminal alkynes. As an addnl. practicality, similar reaction conditions allowed for the use of aromatic amines as radical precursors in a cross dehydrogenative coupling for the direct vinylation of inactivated C-H bonds. In the experiment, the researchers used 4-Ethynylpyridine(cas: 2510-22-7Recommanded Product: 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Design, synthesis, characterization of peripherally tetra-pyridine-triazole-substituted phthalocyanines and their inhibitory effects on cholinesterases (AChE/BChE) and carbonic anhydrases (hCA I, II and IX)》 was published in Dalton Transactions in 2020. These research results belong to Arslan, Tayfun; Bugrahan Ceylan, M.; Bas, Huseyin; Biyiklioglu, Zekeriya; Senturk, Murat. Quality Control of 4-Ethynylpyridine The article mentions the following:

In this study, phthalocyanine precursors (5 and 9) and 1,2,3-triazole-substituted metal-free and metallo phthalocyanines (9a-c) were designed and synthesized for the first time and evaluated in vitro for key mol. targets. The structures of the novel compounds were characterized via FT-IR, 1H/13C NMR, UV-Vis, and mass spectroscopy. The inhibitory activities of the compounds were tested against human carbonic anhydrase isoforms hCA I, II (cytosolic, ubiquitous isoenzymes), and IX (transmembrane, cancer-associated isoenzyme) and cholinesterases (AChE and BChE, which are associated with Alzheimer’s disease). Among the three phthalocyanines and starting compounds, 9b showed the most interesting profile as a nanomolar selective inhibitor of hCA I (Ki = 37.2 nM) and 9c showed the most effective inhibitory effect on hCA II, IX, AChE and BChE (Ki = 41.9, 27.4, 5.8 and 45.8 nM, resp.). This study is also the first example of cancer-associated isoenzyme hCA IX inhibition by phthalocyanines. The experimental process involved the reaction of 4-Ethynylpyridine(cas: 2510-22-7Quality Control of 4-Ethynylpyridine)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Quality Control of 4-Ethynylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Mechanosynthesis of Noels-type NHC-Ruthenium Complexes and Applications in Ring-Opening Metathesis Polymerization》 was published in Organometallics in 2020. These research results belong to Quintin, Francois; Pinaud, Julien; Lamaty, Frederic; Bantreil, Xavier. Synthetic Route of C6H7Br2N The article mentions the following:

The use of ball-mills enabled the efficient mechanosynthesis of a variety of N-aryl,N-alkyl imidazolium salts and of corresponding NHC Ag(I) complexes. Transmetalation with Ru via mechanochem. allowed the rapid access (1.5 min to 1 h) to complexes having a similar structure to Noels-type precatalysts. Evaluation of the complexes in the ring-opening metathesis polymerization of norbornene in different solvent, including nontoxic ones, showed a high catalytic activity for one of them, comparable to the one of Noels catalyst.2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Synthetic Route of C6H7Br2N) was used in this study.

2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Synthetic Route of C6H7Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Acylation of 2-benzylpyridine N-oxides and subsequent in situ [3,3]-sigmatropic rearrangement reaction》 was published in Tetrahedron Letters in 2020. These research results belong to Jing, Hua-qing; Li, Hong-liang; Antilla, Jon C.. Application In Synthesis of 2-Bromo-5-methylpyridine The article mentions the following:

An effective method for the acylation of 2-benzylpyridine N-oxides and their fast in situ [3,3]-sigmatropic rearrangement was reported. This transformation has a wide substrate scope under mild conditions, giving moderate to excellent yields. The application for the synthesis of chiral phenyl-2-pyridylmethanol products was briefly explored. Furthermore, an interesting example of tandem substitution and in situ [3,3]-sigmatropic rearrangement of 2-benzylpyridine N-oxide with benzenecarboximidoyl chloride was reported. In addition to this study using 2-Bromo-5-methylpyridine, there are many other studies that have used 2-Bromo-5-methylpyridine(cas: 3510-66-5Application In Synthesis of 2-Bromo-5-methylpyridine) was used in this study.

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Application In Synthesis of 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《One-Pot Synthesis of Indoles and Pyrazoles via Pd-Catalyzed Couplings/Cyclizations Enabled by Aqueous Micellar Catalysis》 was written by Landstrom, Evan B.; Akporji, Nnamdi; Lee, Nicholas R.; Gabriel, Christopher M.; Braga, Felipe C.; Lipshutz, Bruce H.. Application In Synthesis of 2-Bromo-5-methylpyridine And the article was included in Organic Letters in 2020. The article conveys some information:

An effective one-pot synthesis of either indoles or pyrazoles can be achieved via Pd-catalyzed aminations followed by subsequent cyclizations facilitated by aqueous micellar catalysis. This new technol. includes efficient couplings with low loadings of palladium, a more stable source of the required hydrazine moiety, greater atom economy for the initial coupling, and reduced reaction temperatures, all leading to environmentally responsible processes. In the part of experimental materials, we found many familiar compounds, such as 2-Bromo-5-methylpyridine(cas: 3510-66-5Application In Synthesis of 2-Bromo-5-methylpyridine)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Application In Synthesis of 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《ON/OFF Photoswitching and Thermoinduced Spin Crossover with Cooperative Luminescence in a 2D Iron(II) Coordination Polymer》 was written by Ghosh, Subrata; Kamilya, Sujit; Pramanik, Titas; Rouzieres, Mathieu; Herchel, Radovan; Mehta, Sakshi; Mondal, Abhishake. Related Products of 2510-22-7 And the article was included in Inorganic Chemistry in 2020. The article conveys some information:

A 2D coordination polymer, {[Fe(L)2(NCSe)2]·6MeOH·14H2O}n (1; L = 2,5-dipyridylethynylene-3,4-ethylenedioxythiophene), has been synthesized based on a redox active luminescence ligand. 1 possesses a 2D [4 x 4] square-grid network where the iron(II) center is in a FeN6 octahedral coordination environment. 1 displays reversible thermoinduced high-spin (HS; S = 2) to diamagnetic low-spin (LS; S = 0) ON/OFF spin-state switching with a T1/2 value of 150 K. Interestingly, optical reflectivity and photomagnetic studies at 10 K under light irradiation revealed an efficient conversion to a photoinduced metastable HS excited state from a LS ground state. Remarkably, the photoexcited HS state can be reversibly switched ON and OFF by using 625 and 850 nm light-emitting-diode lights. Intriguingly, the thermal dependence of the luminescence intensity of the maximum emission at 524 nm for 1 shows a min. at around the spin-crossover (SCO) temperature, indicating a cooperative nature between the SCO and luminescence properties. Theor. calculations confirmed the above findings. A 2D [4 x 4] square-grid iron(II) coordination polymer based on a 3,4-ethylenedioxythiophene-containing redox active luminescence ligand has been investigated. Temperature and/or light irradiation significantly alters the cooperative magnetic and optical properties, implying that the material exhibits reversible thermo- and photoinduced ON/OFF spin-state switching behavior with cooperative luminescence properties. The experimental process involved the reaction of 4-Ethynylpyridine(cas: 2510-22-7Related Products of 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Related Products of 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《A nitrogen-doped nanotube molecule with atom vacancy defects》 was written by Ikemoto, Koki; Yang, Seungmin; Naito, Hisashi; Kotani, Motoko; Sato, Sota; Isobe, Hiroyuki. Recommanded Product: 2,6-Dibromopyridine And the article was included in Nature Communications in 2020. The article conveys some information:

Nitrogen-doped carbon nanotubes have attracted attention in various fields, but lack of congeners with discrete mol. structures has hampered developments based on in-depth, chem. understandings. In this study, a nanotube mol. doped periodically with multiple nitrogen atoms has been synthesized by combining eight 2,4,6-trisubstituted pyridine units with thirty-two 1,3,5-trisubstituted benzene units. A synthetic strategy involving geodesic phenine frameworks is sufficiently versatile to tolerate pyridine units without requiring synthetic detours. Crystallog. analyses adopting aspherical multipole atom models reveal the presence of axially rotated structures as a minor disordered structure, which also provides detailed mol. and electronic structures. The nitrogen atoms on the nanotube serve as chem. distinct sites covered with neg. charged surfaces, and they increase the chance of electron injections by lowering the energy levels of the unoccupied orbitals that should serve as electron acceptors. In the experiment, the researchers used many compounds, for example, 2,6-Dibromopyridine(cas: 626-05-1Recommanded Product: 2,6-Dibromopyridine)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Recommanded Product: 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Phosphate and Water Sensing with a Zinc-Dipicolylamine-Based Charge-Transfer Dye》 was written by Gayton, Jacqueline; Autry, Shane A.; Kolodziejczyk, Wojciech; Hill, Glake A.; Hammer, Nathan I.; Delcamp, Jared H.. Recommanded Product: Bis(pyridin-2-ylmethyl)amine And the article was included in ChemistrySelect in 2020. The article conveys some information:

A D-π-A (donor-π bridge-acceptor) dye with a conjugated dipicolylamine group as the donor was synthesized and characterized. When zinc is bound to the dipicolylamine ligand, charge transfer strength from the donor is decreased resulting in a large blue-shift in the absorption spectrum with a quenching of dye emission. Upon addition of phosphate, changes in both the absorption and emission spectrum are observed with intermediate states between the starting zinc complex and free dye observed The zinc-dye complex was found to react with two equivalent of phosphate or trace water to give the free dye. The water response is unexpected given the widespread use of the dipicolylamine group as an anion sensor in water. When the dipicolylamine group is part of conjugated D-π-A dye designs with zinc complexes, the dye is observed to act as a humidity sensor at low water amounts In the part of experimental materials, we found many familiar compounds, such as Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Recommanded Product: Bis(pyridin-2-ylmethyl)amine)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Recommanded Product: Bis(pyridin-2-ylmethyl)amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bag, Sukdev; Jana, Sadhan; Pradhan, Sukumar; Bhowmick, Suman; Goswami, Nupur; Sinha, Soumya Kumar; Maiti, Debabrata published their research in Nature Communications in 2021. The article was titled 《Imine as a linchpin approach for meta-C-H functionalization》.Reference of 5-Bromo-2-chloropyridine The article contains the following contents:

An temporary directing group (TDG) for meta-C-H functionalization via reversible imine formation were reported. By overruling facile ortho-C-H bond activation by imine-N atom, a suitably designed pyrimidine-based TDG successfully delivered selective meta-C-C bond formation. Application of this temporary directing group strategy for streamlining the synthesis of complex organic mols. without any necessary pre-functionalization at the meta position were explored.5-Bromo-2-chloropyridine(cas: 53939-30-3Reference of 5-Bromo-2-chloropyridine) was used in this study.

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Reference of 5-Bromo-2-chloropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem