Month: October 2022

In 2022,Xing, Hao; Yu, Ying; Liu, Junkai; Qin, Peng; Lam, Jacky Wing Yip; Shi, Bingbing; Xie, Guohua; Tang, Ben Zhong published an article in Advanced Optical Materials. The title of the article was 《A Discrete Platinum(II) Metallacycle Harvesting Triplet Excitons for Solution-Processed Deep-Red Organic Light-Emitting Diodes》.Safety of 4-Ethynylpyridine The author mentioned the following in the article:

Platinum(II) coordination-driven architectures have exhibited unique features in fabricating functional supramol. materials. By introducing luminescent moieties into the ligand structure, various light-emitting metallacycles and metallacages have been facilely prepared, presenting specific applications in chem. sensing, light-harvesting, and bio-imaging. Except for building up the metal-ligand bonds, the platinum(II) center should also benefit the ultimate luminescence due to its unique photophys. traits. Here, a platinum(II) metallacycle with deep-red emission for solution-processed organic light-emitting diodes is reported. This metallacycle is assembled by mixing a 180° di-Pt(II) acceptor with a pyridyl-decorated ligand functionalized by a deep-red fluorescent emitter. Notably, the platinum(II) acceptor permits the efficient intramol. transfer of all elec. generated singlet and triplet excitons from itself to the fluorescent moiety, which dramatically enhances the external quantum efficiency of the device compared with the one consisting of the sole ligand. The present results reveal the function of platinum(II) metallacycles in light-emitting devices, a finding which should apply to other coordination-driven architectures with versatile properties. The experimental process involved the reaction of 4-Ethynylpyridine(cas: 2510-22-7Safety of 4-Ethynylpyridine)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Safety of 4-Ethynylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Jin, Yaping; Wang, Ting; Che, Xuefu; Dong, Jianhao; Li, Qingfeng; Yang, Jingshuai published an article in Journal of Power Sources. The title of the article was 《Poly(arylene pyridine)s: New alternative materials for high temperature polymer electrolyte fuel cells》.Synthetic Route of C7H7NO The author mentioned the following in the article:

Developing high-performance and low-cost high temperature polymer exchange membranes (HT-PEMs) is a huge challenge to fuel cells. Here, two poly(arylene pyridine)s (PTAP and PBAP) are synthesized through a simple one-step Friedel-Crafts polymerization of 4-acetylpyridine and para-terphenyl/biphenyl. Both PTAP and PBAP exhibit superior organic solubility and excellent thermal stability. Owing to pyridine groups, PBAP and PTAP membranes display excellent phosphoric acid (PA) absorption capability. The PTAP membrane achieves a PA uptake of 220% after immersing in 85 wt% PA solution at 100 °C, and a high conductivity of 0.102 S cm-1 at 180 °C. Specially, PBAP and PTAP also possess remarkable chem. stability. After 450 h Fenton test, the PTAP membrane still exhibits a high PA uptake of 200% and high conductivity of 0.086 S cm-1. A single H2-O2 cell based on the PTAP/220% membrane shows a peak power d. of 743 mW cm-2 at 180 °C without any back pressure, which also displays excellent durability under 200 mA cm-2 and 400 mA cm-2 at 160 °C. Thus, this work develops a facile, cost effective and up-scalable synthetic route of alternative HT-PEM under mild conditions, comparing with the state-of-the-art polybenzimidazole (PBI) membrane.4-Acetylpyridine(cas: 1122-54-9Synthetic Route of C7H7NO) was used in this study.

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Synthetic Route of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application In Synthesis of Picolinic acidIn 2020 ,《Ilex paraguariensis, white mulberry and chromium picolinate in patients with pre-diabetes》 appeared in Phytotherapy Research. The author of the article were Derosa, Giuseppe; D’Angelo, Angela; Maffioli, Pamela. The article conveys some information:

To evaluate if a nutraceutical compound containing Ilex paraguariensis, White Mulberry and Chromium Picolinate can ameliorate glycemic status in patients with pre-diabetes. We enrolled patients with IFG or IGT, not taking other hypoglycemic compounds Patients were randomized to take placebo or the nutraceutical compound for 3 mo, in a randomized, double-blind, placebo-controlled design. Both treatments were self-administered once a day, 1 tablet during the breakfast. A reduction of FPG was observed with the nutraceutical combination (-7.8%). Furthermore, there was a decrease of HOMA-IR with the nutraceutical combination (-7.9%). M value was higher (p < 0.05 vs baseline and p < 0.05 vs placebo) at the end of the treatment. We obtained a reduction of Tg with the nutraceutical combination (-8.3%). About 16.6% of patients treated with nutraceutical returned to have a normal glycemia (< 100 mg/dL), and all patients had an improvement of insulin-resistance, in particular 67% of patients returned to have a M value inside range of normal insulin sensitivity. A nutraceutical containing Ilex paraguariensis, White Mulberry and Chromium Picolinate at 500 mg can be helpful in improving glycemia and Tg value, in patients with pre-diabetes. The experimental part of the paper was very detailed, including the reaction process of Picolinic acid(cas: 98-98-6Application In Synthesis of Picolinic acid)

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Application In Synthesis of Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Category: pyridine-derivativesIn 2021 ,《Covalent immobilization of ruthenium polypyridyl complex on multi-walled carbon nanotube supports for oxygen evolution reaction in an alkaline solution》 was published in Journal of Power Sources. The article was written by Wu, Zhen-Yi; Zhang, Qian-Xin; Huang, Li-Jing; Xu, Yu-Jin; Tang, Ding-Liang. The article contains the following contents:

Electrocatalytic water splitting to realize the sustainable production of hydrogen is one of the key ways to gain renewable clean energy. The development of the ruthenium-terpyridine-bipyridine (bpyRutpy) complexes used as efficient homogeneous water oxidation catalysts is one of the currently hot research fields. All catalytic active sites of the homogeneous mol. catalyst are fully utilized, and show a high catalytic efficiency. However, the homogeneous mol. catalyst has some intrinsic shortages such as difficulty on separation, recovery and regeneration, and high cost. In view of this, we synthesized the multi-walled carbon nanotube (MWCNT)-based heterogeneous catalyst, MWCNT-bpyRutpy, by covalently bonding the ruthenium-based complex onto the carbon nanotubes, in order to achieve the maximum mol. catalytic efficiency of the complex. The synthesized catalyst is fully characterized by mass spectrometry, NMR spectroscopy, IR spectroscopy, UV-visible spectroscopy, photoelectron spectroscopy, Raman spectroscopy, and thermogravimetry. The formation of the nanocatalyst via fusing Ruthenium complexes to MWCNTs promotes the oxygen evolution reaction (OER) kinetics, enhances intrinsic activity, and increases the sp. surface area of electrochem. activity, and achieve excellent OER performance with a low overpotential of 436 mV at 10mAcm2, a low Tafel slope of 77.2 mV, and a relatively high turnover frequency (TOF) of 0.5833 s-1 at an overpotential of 400 mV. In the experiment, the researchers used 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Category: pyridine-derivatives)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.Category: pyridine-derivatives Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Formula: C5H3Br2NIn 2021 ,《Stimuli-responsive cyclometalated platinum complex bearing bent molecular geometry for highly efficient solution-processable OLEDs》 was published in Chinese Chemical Letters. The article was written by Wei, Zhenhua; Zhang, Kai; Kim, Chan Kyung; Tan, Shuai; Wang, Shaojie; Wang, Lin; Li, Jun; Wang, Yafei. The article contains the following contents:

Smart materials, such as stimuli-responsive luminescence, have attracted much attentions due to their potential application in semiconductor filed. In this context, Pt complexes of (dfppy-DC)Pt(acac) and (dfppy-O-DC)Pt(acac) were prepared and characterized, in which (2-(4′,6′-difluorophenyl)pyridinato-N,C2′)(2,4-pentanedionato-O,O)Pt(II) was used as the planar emission core and 9-(4-(phenylsulfonyl)phenyl)-9H-carbazole (d.c.) was regard as the bent pendent. Both Pt complexes showed bright emission in solution and solid state, concomitant with charming external-stimuli-responsive emission under mech. grinding, organic solvent vapors and pressure. The change emission color spanned from yellow to near-IR region. Using the Pt complexes as the dopant, solution processable organic light-emitting diodes (OLEDs) were fabricated and a maximum external quantum efficiency of -18% was achieved, which is the highest value among the reported solution-processable OLEDs based on external-stimuli-responsive luminescence. This research demonstrated that Pt complex can show promising stimuli responsive emission via ingenious mol. design, indicating a novel way for developing the smart materials in semiconductor filed. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromopyridine(cas: 624-28-2Formula: C5H3Br2N)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Formula: C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Recommanded Product: 128071-75-0In 2021 ,《Microwave accelerated Castagnoli-Cushman reaction: Synthesis of novel 6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazines》 was published in Tetrahedron Letters. The article was written by Vytla, Devaiah; Shaw, Parinita; Velayuthaperumal, Rajeswari; Emmadi, Jithendra; Mathur, Arvind; Roy, Amrita. The article contains the following contents:

The Castagnoli-Cushman reaction of various azaindole dicarboxylic acids with imines using acetic anhydride as a dehydrating agent was significantly accelerated by microwave irradiation The reaction conditions offered a convenient preparation of novel 6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazines I [R1 = H, MeO, Cl, X = CH, N; Y = CH, N; Z = CH, N; R2 = 4-MeC6H4, 3-FC6H4, 4-MeOC6H4, 4-NO2C6H4, 2-thienyl; R3 = n-Pr, cyclopropyl, 4-MeC6H4, etc.] in moderate to good yields with good trans stereoselectivity. In the experiment, the researchers used many compounds, for example, 2-Bromonicotinaldehyde(cas: 128071-75-0Recommanded Product: 128071-75-0)

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Recommanded Product: 128071-75-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《An improved synthesis of (hydroxymethyl)bipyridines》 was written by Smith, Adam P.; Corbin, Perry S.; Fraser, Cassandra L.. Formula: C12H10Cl2N2 And the article was included in Tetrahedron Letters on April 15 ,2000. The article conveys some information:

Quick and efficient syntheses of 4,4′-bis(hydroxymethyl)-2,2′-bipyridine and 4-(hydroxymethyl)-2,2′-bipyridine are described starting from 4,4′-dimethyl-2,2′-bipyridine and 4-methyl-2,2′-bipyridine, resp., via (trimethylsilyl)methyl-, bromomethyl-, and acetoxymethyl intermediates. After reading the article, we found that the author used 4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4Formula: C12H10Cl2N2)

4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. Formula: C12H10Cl2N2 Pyridine has a conjugated system of six π electrons that are delocalized over the ring.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Selective recognition of Zn(II) ions in live cells based on chelation enhanced near-infrared fluorescent probe》 was written by Zhang, Yibin; Yuan, Binfang; Ma, Dongge. Synthetic Route of C12H13N3This research focused onZn chelation IR fluorescent probe. The article conveys some information:

A near-IR fluorescent (NIR) probe NR-Zn (I), which consists of a dicyanoisophorone derivative and an Zn(II) ion recongnitive dipicolylamine moiety, was synthesized and applied to detect Zn(II) ions concentration change in living cell. This NR-Zn probe exhibits a strong turn-on fluorescence response toward Zn(II) ions when excited at 545 nm and has other advantages, such as rapid response (<20 s), large Stokes shift (131 nm), low cytotoxicity and good photostability. Moreover, it has been succesfully applied to monitor Zn(II) ions in Hela cells. In addition to this study using Bis(pyridin-2-ylmethyl)amine, there are many other studies that have used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Synthetic Route of C12H13N3) was used in this study.

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Synthetic Route of C12H13N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Single-component white polymer light-emitting diode (WPLED) based on a binary tris-pyrazolonate-Sm-complex》 was written by Liu, Jiaxiang; Li, Wentao; Wang, Baowen; He, Yani; Miao, Tiezheng; Lu, Xingqiang; Fu, Guorui. Synthetic Route of C5H3Br2NThis research focused ontrispyrazolonate samerium complex white polymer light emitting diode. The article conveys some information:

Based on the doping of the binary tris-pyrazolate-Sm3+ complex [Sm(tba-PMP)3(5-Br-2,2′-bpy)] (1; 5-Br-2,2′-bpy = 5-bromo-2,2′-bipyridine and (Htba-PMP = 1-phenyl-3-methyl-4-(tert-butylacetyl)-5-pyrazolone)) with an efficient orange-light into the PVK (poly(N-vinylcarbazole)) host, the obtained PVK@1 films exhibit the dichromatic color-tuning (white-light to purplish-pink and to pink) characters strictly relative to the Sm3+-doping content and the λex wavelength. Further using the PVK@1 film (10:1; wt/wt) with the straightforward white-light (φPL = 5.8%) as the emitting layer, its single-component solution-processed WPLED gives the electroluminescent performance (LMax of 157 cd/m2, ηMaxc of 0.65 cd/A and the white-light-emitting stability) satisfactory enough for portable full-color flat displays. In the experimental materials used by the author, we found 2,5-Dibromopyridine(cas: 624-28-2Synthetic Route of C5H3Br2N)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Synthetic Route of C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Auvray, Thomas; Del Secco, Benedetta; Dubreuil, Amelie; Zaccheroni, Nelsi; Hanan, Garry S. published an article on January 4 ,2021. The article was titled 《In-Depth Study of the Electronic Properties of NIR-Emissive κ3N Terpyridine Rhenium(I) Dicarbonyl Complexes》, and you may find the article in Inorganic Chemistry.Electric Literature of C20H14N4 The information in the text is summarized as follows:

The structure-properties relationship in a series of carbonyl rhenium(I) complexes based on substituted terpyridine ligands of general formula [Re(κxN-Rtpy)(CO)yL]n+ is explored by both exptl. and theor. methods. In these compounds, the terpyridine ligands adopt both bidentate (κ2N) and terdentate (κ3N) coordination modes associated with three or two carbonyls, resp. Conversion from the κ2N to the κ3N coordination mode leads to large changes in the absorption spectra and oxidation potentials due to destabilization of the HOMO level of each complex. The absorption profiles of the κ3N complexes cover the whole visible spectra with lower maxima around 700 nm, tailing out to 800 nm, while no emission is observed with Br- as the axial ligand L. When the axial ligand is modified from the native halide to pyridine or triphenylphosphine, the lowest absorption band is blue-shifted by 60 and 90 nm, resp. These cationic complexes are near-IR emitters with emission maxima between 840 and 950 nm for the pyridine compounds and 780-800 nm for the triphenylphosphine compounds Conversion from the κ2N to the κ3N coordination mode of the terpyridine ligand in Re(I) carbonyl complexes leads to major changes in their electronic properties. The absorption profiles of the κ3N complexes cover the whole visible spectra and can be finely tuned by changing the ancillary ligand L. For complexes with L = pyridine. PPh3, near-IR emission (780-950 nm) with unusually high quantum yields (0.02-0.7%) for this class of compounds is reported. After reading the article, we found that the author used 4′-(4-Pyridyl)-2,2′:6′,2”-terpyridine(cas: 112881-51-3Electric Literature of C20H14N4)

4′-(4-Pyridyl)-2,2′:6′,2”-terpyridine(cas: 112881-51-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. Electric Literature of C20H14N4The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem