Month: October 2022

《A visible-light-photocatalytic water-splitting strategy for sustainable hydrogenation/deuteration of aryl chlorides》 was published in Science China: Chemistry in 2020. These research results belong to Ling, Xiang; Xu, Yangsen; Wu, Shaoping; Liu, Mofan; Yang, Peng; Qiu, Chuntian; Zhang, Guoqiang; Zhou, Hongwei; Su, Chenliang. Application In Synthesis of 5-Bromo-2-chloropyridine The article mentions the following:

Abstract: Hydrogenation/deuteration of carbon chloride (C-Cl) bonds is of high significance but remains a remarkable challenge in synthetic chem., especially using safe and inexpensive hydrogen donors. In this article, a visible-light-photocatalytic water splitting hydrogenation technol. (WSHT) is proposed to in-situ generate active H-species (i.e., Had) for controllable hydrogenation of aryl chlorides instead of using flammable H2. When applying heavy water-splitting systems, we could selectively install deuterium at the C-Cl position of aryl chlorides under mild conditions for the sustainable synthesis of high-valued added deuterated chems. Sub-micrometer Pd nanosheets (Pd NSs) decorated crystallined polymeric carbon nitrides (CPCN) is developed as the bifunctional photocatalyst, whereas Pd NSs not only serve as a cocatalyst of CPCN to generate and stabilize H (D)-species but also play a significant role in the sequential activation and hydrogenation/deuteration of C-Cl bonds. This article highlights a photocatalytic-WSHT for controllable hydrogenation/deuteration of low-cost aryl chlorides, providing a promising way for the photosynthesis of high-valued added chems. instead of the hydrogen evolution. After reading the article, we found that the author used 5-Bromo-2-chloropyridine(cas: 53939-30-3Application In Synthesis of 5-Bromo-2-chloropyridine)

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Application In Synthesis of 5-Bromo-2-chloropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Coumarin-Based Reversible Fluorescent Probe for Selective Detection of Cu2+ in Living Cells》 was published in Journal of Fluorescence in 2020. These research results belong to Ahmed, Nadeem; Zareen, Wajeeha; Zhang, Di; Yang, Xiaopeng; Ye, Yong. HPLC of Formula: 1539-42-0 The article mentions the following:

Abstract: Copper ion plays an important role in many biol. processes in human body. H2S is considered as the third gasses transmitter after carbon monoxide and nitric oxide. Here a novel ICT-based fluorescent ON-OFF-ON probe for Cu2+ and H2S detection was developed. Selectivity and sensitivity of probe was confirmed in aqueous Tris-HCl buffer (10 mM, pH 7.4, containing 90% acetonitrile). Probe DF-CU shows high selectivity over other analytes. The degree of fluorescence quenching is linearly associated with the concentration of Cu2+ (R2 = 0.9919). The limit of detection (LOD, calculated according to the 3σ/slope) for Cu2+ was 6.4μM. Probe can work in almost all pH. The probe shows a very fast response to Cu2+ (within 10 s). Its response to copper ion could be reversed by H2S. The complex of probe with Cu2+ could be used for H2S detection. Furthermore, this ON-OFF-ON fluorescent probe successfully applied in the living cells for the detection of Cu2+ and H2S. In addition to this study using Bis(pyridin-2-ylmethyl)amine, there are many other studies that have used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0HPLC of Formula: 1539-42-0) was used in this study.

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. HPLC of Formula: 1539-42-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Cavity-directed nitroaromatics sensing within a carbazole-based luminescent supramolecular M2L3 cage》 was published in Chinese Chemical Letters in 2020. These research results belong to Feng, Tianchi; Li, Xuezhao; Wu, Jinguo; He, Cheng; Duan, Chunying. Quality Control of 2,5-Dibromopyridine The article mentions the following:

The design and preparation of luminescent M2L3 metal-organic cage via the coordination-driven self-assembly of carbazole-based ligand with a V-shaped geometry is described. The cage Zn-L1 with an open cavity which equipped aromatic rich ligands shows the highest emission quenching efficiency towards picric acid than other nitroarom. explosives. The quenching ability depended on whether there formed the host-guest mols. are well explored by electrospray ionization mass spectrometry (ESI-MS), and isothermal titration microcalorimetry (ITC). The results came from multiple reactions, including the reaction of 2,5-Dibromopyridine(cas: 624-28-2Quality Control of 2,5-Dibromopyridine)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Quality Control of 2,5-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Structural Variety in Mn(NCS)2 4-Cyanopyridine Coordination Compounds: Synthesis, Structures, Isomerism, and Magnetic Properties》 was written by Wellm, Carsten; Neumann, Tristan; Gallo, Gianpiero; Dziubyna, Anna M.; Rams, Michal; Dinnebier, Robert E.; Naether, Christian. Quality Control of 4-Cyanopyridine And the article was included in Crystal Growth & Design in 2020. The article conveys some information:

The reaction of Mn(NCS)2 with 4-cyanopyridine (CNpy) gives discrete complexes [Mn(NCS)2(CNpy)4] (1), [Mn(NCS)2(H2O)2(CNpy)2] (2-I and 2-II), and [Mn(NCS)2(H2O)2(CNpy)2]·xCNpy (x = 4, 3; x = 2, 4), in which the Mn(II) centers are octahedrally coordinated by two terminal N-bonded thiocyanate anions and by four (1) or two CNpy coligands and two H2O mols. (2-I, 2-II, 3, and 4). If an excess of Mn(NCS)2 was used, [Mn(NCS)2(CNpy)2]n (5) and [Mn(NCS)2(CNpy)]n (6-I and 6-II) were obtained. In all compounds the Mn(II) cations are octahedrally coordinated and linked into linear chains (5), into layers (6-I), or into a 3-dimensional network (6-II) by the thiocyanate anions. Studies using TG-DTA and temperature-dependent powder x-ray diffraction prove that the discrete complexes 2-II, 3, and 4 decompose in several steps, giving Mn(NCS)2 via 5 and 6-I as intermediates. For compounds 2-II, 4, and 6-II only one batch was obtained, indicating that these compounds are metastable. Magnetic measurements for 5 and 6-I reveal dominating antiferromagnetic interactions and susceptibility curve maxima at 20 K (5) and 24 K (6-I), reproduced by quantum Monte Carlo simulations. The sp. heat proves magnetic ordering at 2.8 K (5) and 12.4 K (6-I). The ordering of 6-I is associated with a weak ferromagnetism. Several Mn(NCS)2 4-cyanopyridine coordination compounds including polymorphic and isomeric modifications were synthesized and structurally characterized by SC-XRD and PXRD. Their thermal reactivity and magnetic behavior were studied. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Quality Control of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Quality Control of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《High performance of nitrogen-doped carbon-supported cobalt catalyst for the mild and selective synthesis of primary amines》 was written by Liu, Xixi; Wang, Yanxin; Jin, Shiwei; Li, Xun; Zhang, Zehui. Recommanded Product: 100-48-1 And the article was included in Arabian Journal of Chemistry in 2020. The article conveys some information:

A nitrogen-doped carbon-supported Co catalyst (Co/N-C-800) was discovered to be highly active for the reductive amination of carbonyl compounds with NH3 and the hydrogenation of nitriles into primary amines using H2 as the hydrogen source. Structurally diverse carbonyl compounds were selectively transformed into primary amines with good to excellent yields (82.8-99.6%) under mild conditions. The Co/N-C-800 catalyst showed comparable or better catalytic performance than the reported noble metal catalysts. The Co/N-C-800 catalyst also showed high activity for the hydrogenation of nitriles, affording the corresponding primary amines with high yields (81.7-99.0%). An overall reaction mechanism is proposed for the reductive amination of benzaldehyde and the hydrogenation of benzonitrile, which involves the same intermediates of phenylmethanimine and N-benzylidenebenzylamine. After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Recommanded Product: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Recommanded Product: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Encapsulation of Phosphorescent Pt(II) Complexes in Zn-Based Metal-Organic Frameworks toward Oxygen-Sensing Porous Materials》 was written by Knedel, Tim-Oliver; Buss, Stefan; Maisuls, Ivan; Daniliuc, Constantin G.; Schluesener, Carsten; Brandt, Philipp; Weingart, Oliver; Vollrath, Annette; Janiak, Christoph; Strassert, Cristian A.. Name: 2,6-Dibromopyridine And the article was included in Inorganic Chemistry in 2020. The article conveys some information:

In this work, two tailored phosphorescent Pt(II) complexes are synthesized bearing a cyclometalating tridentate thiazole-based C^N*N pincer luminophore (L) and exchangeable chlorido ([PtCl(L)]) or cyanido ([PtCN(L)]) coligands. While both complexes showed photoluminescence from metal-perturbed ligand-centered triplet states (3MP-LC), [PtCN(L)] reached the highest phosphorescence quantum yields and displayed a significant sensitivity toward quenching by 3O2. They were encapsulated into two Zn-based metal-organic frameworks, namely, MOF-5 and ZIF-8. The incorporation of the organometallic compounds in the resulting composites [PtCl(L)]@ZIF-8, [PtCN(L)]@ZIF-8, [PtCl(L)]@MOF-5 and [PtCN(L)]@MOF-5 was verified by powder X-ray diffractometry, SEM, time-resolved photoluminescence spectroscopy and microscopy, as well as N2- and Ar-gas sorption studies. The amount of encapsulated complex was determined by graphite furnace at. absorption spectroscopy, showing a maximum loading of 3.7 wt %. If compared with their solid state forms, the solid-solution composites showed prolonged 3O2-sensitive excited state lifetimes for the complexes at room temperature, reaching up to 18.4μs under an Ar atm., which is comparable with the behavior of the complex in liquid solutions or even frozen glassy matrixes at 77 K. Two tailored phosphorescent Pt(II) complexes were synthesized bearing a cyclometalating tridentate thiazole-based C^N*N pincer luminophore and exchangeable coligands. They were encapsulated into two Zn-based metal-organic frameworks, namely, MOF-5 and ZIF-8. If compared with their liquid solutions, the solid-solution composites showed prolonged 3O2-sensitive excited state lifetimes for the complexes at room temperature, reaching up to 18.4μs under an Ar atm., which is comparable with the behavior of the complex in frozen glassy matrixes at 77 K.2,6-Dibromopyridine(cas: 626-05-1Name: 2,6-Dibromopyridine) was used in this study.

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Name: 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yuan, Lei; Gao, Hongshuai; Jiang, Haiyan; Zeng, Shaojuan; Li, Tao; Ren, Baozeng; Zhang, Xiangping published their research in Journal of Molecular Liquids in 2021. The article was titled 《Experimental and thermodynamic analysis of NH3 absorption in dual-functionalized pyridinium-based ionic liquids》.Related Products of 103-74-2 The article contains the following contents:

A novel type of dual-functionalized pyridinium-based ionic liquids (ILs) with acidic protons and hydroxyl groups, were designed and synthesized for ammonia (NH3) absorption. The NH3 absorption isotherms in dualfunctionalized pyridinium-based ILs at temperatures from 303.15 to 343.15 K and pressures up to 600 kPa were computed using gas-liquid equilibrium method. It revealed that 4-pyridinemethanol bis (trifluoromethane)sulfonamide [4-MeOHPy][NTf2] showed the maximum NH3 solubility of 3.43 mol NH3/mol IL at 313.15 K and atm. pressure, surpassing any nonmetallic ILs previously reported. Furthermore, the characteristics of isotherms under low pressures behaved an obvious chem. reaction between ILs and NH3, and all exptl. solubilities were regulated by a reaction equilibrium thermodn. model (RETM). The thermodn. properties were further obtained to better understand the NH3 absorption process. The results indicated that this model endorses the 1:1 (NH3-IL) mole ratio of chem. reaction mechanism and the reaction enthalpy is main driving force of NH3 absorption in ILs. In the experimental materials used by the author, we found 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Related Products of 103-74-2)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Related Products of 103-74-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Liu, Weiwei; Li, Ruihua; Deng, Fei; Yan, Chunyu; Zhou, Xuelian; Miao, Lu; Li, Xiaolian; Xu, Zhaochao published their research in ACS Applied Bio Materials in 2021. The article was titled 《A Cell Membrane Fluorogenic Probe for Gram-Positive Bacteria Imaging and Real-Time Tracking of Bacterial Viability》.Application In Synthesis of Bis(pyridin-2-ylmethyl)amine The article contains the following contents:

Bacterial infections are a global healthcare problem, resulting in serious clin. morbidities and mortality. Real-time monitoring of live bacteria by fluorescent imaging technol. has potential in diagnosis of bacterial infections, elucidating antimicrobial agents′ mode of action, assessing drug toxicity, and examining bacterial antimicrobial resistance. A naphthalimide-derived fluorescent probe ZTRS-BP was developed for wash-free Gram-pos. bacteria imaging. The probe aggregated in aqueous solutions and exhibited aggregation-caused fluorescence quenching (ACQ). The interaction with Gram-pos. bacteria cell walls would selectively disaggregate the probe and the liberated probes were dispersed on the outside of the bacteria cell walls to achieve surface fluorescence imaging. There were no such interactions with Gram-neg. bacteria, which indicates that selective binding and imaging of Gram-pos. bacteria was achieved. The binding of zinc ions by ZTRS-BP can enhance the fluorescent signals on the bacterial surface by inhibiting the process of photoinduced electron transfer. ZTRS-BP-Zn(II) complex was an excellent dye to discriminate mixed Gram-pos. and Gram-neg. bacteria. Also, live and dead bacteria can be differentially imaged by ZTRS-BP-Zn(II). Furthermore, ZTRS-BP-Zn(II) was used for real-time monitoring bacteria viability such as B. cereus treated with antibiotic vancomycin. In addition to this study using Bis(pyridin-2-ylmethyl)amine, there are many other studies that have used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Application In Synthesis of Bis(pyridin-2-ylmethyl)amine) was used in this study.

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. Application In Synthesis of Bis(pyridin-2-ylmethyl)amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bhowmick, Indrani; Newell, Brian S.; Shores, Matthew P. published their research in Dalton Transactions in 2021. The article was titled 《A systematic study of the influence of ligand field on the slow magnetic dynamics of Co(II)-diimine compounds》.Synthetic Route of C12H12N2 The article contains the following contents:

Herein the authors report heteroleptic Co(II) diimine complexes [Co(H2bip)2Cl2] (1), [Co(H2bip)2Br2] (2), [Co(H2bip)3]Br2·MeOH (3) and [Co(H2bip)2(Me2bpy)]Br2·(MeCN)0.5·(H2O)0.25 (4) (H2bip = 2,2′-bi-1,4,5,6-tetrahydropyrimidine, bpy = 2,2′-dipyridyl, Me2bpy = 4,4′-Me-2,2′-dipyridyl), purposefully prepared to enable a systematic study of magnetic property changes arising from the increase of overall ligand field from σ/π-donor chlorido in 1 to π-acceptor 4,4’Me-2,2’bpy in 4. The axial and rhombic anisotropy (D and E) of these compounds is sufficient to allow 1-4 to show field-induced slow relaxation of magnetization. The authors found as the effective ligand field is increased in the series, rhombicity (E/D) decreases, and the magnetic relaxation profile changes significantly, where relaxation of magnetization at a specific temperature becomes gradually faster. The authors performed mechanistic analyses of the temperature dependence of magnetic relaxation times considering Orbach relaxation processes, Raman-like relaxation and quantum tunnelling of magnetization (QTM). The effective energy barrier of the Orbach relaxation process (Ueff) is largest in 1 (19.2 cm-1) and gradually decreases in the order 1 > 2 > 3 > 4 giving a min. value in 4 (8.3 cm-1), where the Raman-like mechanism showed the possibility of different types of phonon activity below and above ~2.5 K. As a precursor of 1, the tetrahedral complex [Co(H2bip)Cl2] (1a) was also synthesized and structurally and magnetically characterized. 1A exhibits slow relaxation of magnetization under an applied d.c. field (1800 Oe) with a record slow relaxation time of 3.39 s at 1.8 K. In the experiment, the researchers used many compounds, for example, 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Synthetic Route of C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Synthetic Route of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rathnayake, Manjula D.; Weaver, Jimmie D. III published their research in Organic Letters in 2021. The article was titled 《Coupling Photocatalysis and Substitution Chemistry to Expand and Normalize Redox-Active Halides》.Product Details of 100-48-1 The article contains the following contents:

Photocatalysis can generate radicals in a controlled fashion and has become an important synthetic strategy. However, limitations due to the reducibility of alkyl halides prevent their broader implementation. Herein authors explore the use of nucleophiles that can substitute the halide and serve as an electron capture motif that normalize the variable redox potentials across substrates. When used with photocatalysis, bench-stable, com. available collidinium salts prove to be excellent radical precursors with a broad scope. The results came from multiple reactions, including the reaction of 4-Cyanopyridine(cas: 100-48-1Product Details of 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Product Details of 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem