Month: October 2022

In 2018,Devi, Namita; Hazarika, Sukanya; Gogoi, Prasanta; Barman, Pranjit published 《A novel dual-nano assisted synthesis of symmetrical disulfides from aryl/alkyl halides》.Synthetic Communications published the findings.Safety of 5-Bromo-2-chloropyridine The information in the text is summarized as follows:

A novel approach towards dual-nano assisted synthesis of disulfides from coupling of alkyl/aryl halides and sulfur nanoparticles has been reported. The indium oxide nanoparticles as catalyst expedite the conversion and sulfur nanoparticles notably enhances the miscibility, providing a faster, high yielding and cost-effective process in an ethanol-water system. The method has synthetic advantages in terms of mild reaction framework, catalyst regeneration, and absence of any sulfide or polysulfide linkage as byproduct leading to a column free synthesis. A variety of alkyl, aryl and heteroaryl sym. disulfides are obtained in good to excellent yields up to 98%.5-Bromo-2-chloropyridine(cas: 53939-30-3Safety of 5-Bromo-2-chloropyridine) was used in this study.

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Safety of 5-Bromo-2-chloropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Inorganica Chimica Acta included an article by Chen, Dong-Mei; Wu, Xiao-Fan; Liu, Yong-Jie; Huang, Chao; Zhu, Bi-Xue. Computed Properties of C7H7NO. The article was titled 《Synthesis, crystal structures and vapor adsorption properties of Hg(II) and Cd(II) coordination polymers derived from two hydrazone Schiff base ligands》. The information in the text is summarized as follows:

Four coordination polymers, [HgL1Br2]n (1), {[Cd(L1)2Cl2]·2CH3OH}n (2), [HgL2Cl2]n (3) and [Cd(L2)2Cl2]n (4), were synthesized and characterized from two hydrazone Schiff base ligands (L1 and L2) with mercury(II) or cadmium(II) halide, resp. In complexes 1 and 3, each mercury(II) center is five-coordinated with distorted square pyramidal geometry in 1-dimensional coordination polymers. In complexes 2 and 4, each cadmium(II) center is six-coordinated with slightly distorted octahedral geometry in 1-dimensional looped-chain structures. The ligands show different coordination sites in the formation of coordination polymers. In complexes 2, 3 and 4, the ligands coordinate to the metal centers by pyridine nitrogen atoms and amino nitrogen atoms, whereas in complex 1 it coordinates by pyridine nitrogen atoms and carbonyl oxygen atoms instead of amino nitrogen atoms. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9Computed Properties of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Computed Properties of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Copper-catalyzed versatile C(sp3)-H arylation: synthetic scope and regioselectivity investigations》 were Zhou, Jiadi; Zou, Yawen; Zhou, Peng; Chen, Zhiwei; Li, Jianjun. And the article was published in Organic Chemistry Frontiers in 2019. Synthetic Route of C6H4N2 The author mentioned the following in the article:

The copper-catalyzed versatile C(sp2)-C(sp3) bond formation with N-heteroaromatics and hydrogen donors was developed. Various alkanes and ethers reacted with quinolines, isoquinolins, pyridines, benzooxazole and benzothiazole to gave the corresponding C(sp2)-H alkylation products via cross-dehydrogenative coupling. The high regioselective C(sp2)-halogen alkylation of (hetero)aryl chlorides and (hetero)aryl bromides with ethers via elimination of the halogen radical. The reaction mechanism was investigated with control experiments The experimental process involved the reaction of 4-Cyanopyridine(cas: 100-48-1Synthetic Route of C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Synthetic Route of C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《A near infrared light emitting electrochemical cell with a 2.3 V turn-on voltage》 were Nemati Bideh, Babak; Shahroosvand, Hashem; Sousaraei, Ahmad; Cabanillas-Gonzalez, Juan. And the article was published in Scientific Reports in 2019. COA of Formula: C12H12N2 The author mentioned the following in the article:

We report on an organic electroluminescent device with simplified geometry and emission in the red to near IR (NIR) spectral region which, has the lowest turn-on voltage value, 2.3 V, among light emitting electrochem. cells (LEECs). We have synthesized and characterized three novel ruthenium π-extended phenanthroimidazoles which differ on their NN̂ ligands. The use of di-Me electron donating groups along with the π-extended phenanthroimidazole moiety promotes ambipolar transport thereby avoiding the use of addnl. charge transport layers. Furthermore, a facile cathode deposition method based on transfer of a molten alloy (Ga:In) on top of the active layer is deployed, thus avoiding high vacuum thermal deposition which adds versatile assets to our approach. We combine ambipolar charge transport organic complex design and a simple ambient cathode deposition to achieve a potentially cost effective red to NIR emitting device with outstanding performance, opening new avenues towards the development of simplified light emitting sources through device optimization. The results came from multiple reactions, including the reaction of 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6COA of Formula: C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.COA of Formula: C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Facile one-pot protocol of derivatization nitropyridines: access to 3-acetamidopyridin-2-yl 4-methylbenzenesulfonate derivatives》 were Lin, Ling; Chen, Xiaoguang; Zhao, Junhao; Lin, Suitao; Ma, Guojian; Liao, Xiaojian; Feng, Pengju. And the article was published in Heterocyclic Communications in 2019. Application In Synthesis of 6-Bromopyridin-3-amine The author mentioned the following in the article:

An efficient one-pot protocol for conversion of easily accessible 3-nitropyridines to 3-acetamidopyridin-2-yl 4-methylbenzenesulfonate derivatives which were core structures of many pharmaceutical mols was reported. The strategy successfully combined a three-step reaction in one-pot via progressively adding different reactants at rt. The reaction displayed good functional group tolerance and regioselectivity. Structurally diversified 3-nitropyridine was time-efficiently (3.5 h) derivatized to various functional 2-O,3-N-pyridines which were apt for further elaborations. The transformation was amenable to gram-scale synthesis. After reading the article, we found that the author used 6-Bromopyridin-3-amine(cas: 13534-97-9Application In Synthesis of 6-Bromopyridin-3-amine)

6-Bromopyridin-3-amine(cas: 13534-97-9) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Application In Synthesis of 6-Bromopyridin-3-amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Improved synthesis of YG-056SP, a potent oxazolidinone antibacterial candidate against multi-drug resistant bacteria》 were Chen, Peng; Zhang, Yinyong; Shi, Chenghui; Meng, Xin; Yang, Yushe; Zhou, Xianli; Guo, Bin. And the article was published in Journal of Chemical Research in 2019. Recommanded Product: 2,5-Dibromopyridine The author mentioned the following in the article:

An improved process for the synthesis of potent oxazolidinone candidate I against multi-drug resistant bacteria was developed. Compared with the original synthetic route, this new approach was two steps shorter, and all of the steps involved simple purifications without column chromatog. More importantly, it avoided the use of explosive azide compounds and expensive metal catalysts. The new reaction conditions were mild and safe, which was more suitable for the scalable synthesis of YG-056SP for preclin. studies. The results came from multiple reactions, including the reaction of 2,5-Dibromopyridine(cas: 624-28-2Recommanded Product: 2,5-Dibromopyridine)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Recommanded Product: 2,5-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Formation of benzodiazepines and pyrazinylquinoxalines from aromatic and heteroaromatic ketones via deoximation》 was published in Asian Journal of Chemistry in 2020. These research results belong to Song, J. H.; Bae, S. M.; Lee, E. J.; Cho, J. H.; Jung, D. I.. Recommanded Product: 1122-54-9 The article mentions the following:

In the course of present investigations, it was found that dichloroamine T could be an efficient reagent for the conversion of oximes into the corresponding carbonyl compounds Herein the synthesis of 1H-1,5-benzodiazepine derivatives I [R = pyrrol-2-yl, 2-pyridinyl, 2-thienyl, etc.] from heteroaromatic ketones and acetone equivalent was obtained using dichloroamine-T. On the other hand, when diamine (1,2-phenylene diamine or 1,2-naphthalene diamine) with heterocyclic ketone (acetyl pyridine or acetyl pyrazines) in the presence of concentrate HCl and SiO2 was refluxed, quinoxaline derivatives, II [R = 2-pyrazinyl, 2-pyridinyl, 2-thienyl, etc.] as yellow crystalline solids were isolated in high yields. In the part of experimental materials, we found many familiar compounds, such as 4-Acetylpyridine(cas: 1122-54-9Recommanded Product: 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Recommanded Product: 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Asymmetric transfer hydrogenation of ketones promoted by manganese(I) pre-catalysts supported by bidentate aminophosphines》 was published in Catalysis Communications in 2020. These research results belong to Azouzi, Karim; Bruneau-Voisine, Antoine; Vendier, Laure; Sortais, Jean-Baptiste; Bastin, Stephanie. COA of Formula: C7H7NO The article mentions the following:

A series of com. available chiral amino-phosphines, in combination with Mn(CO)5Br, was evaluated for the asym. reduction of ketones to secondary alcs. RCH(OH)R1 [R = c-hexyl, Ph, 1-naphthyl, etc.; R1 = Me, Et, i-Pr, etc.] using isopropanol as hydrogen source. With the most selective ligand, the corresponding manganese complex was synthesized and fully characterized. A series of ketones was hydrogenated in the presence of 0.5 mol% of the manganese pre-catalyst affording the chiral alcs. in high yields with enantiomeric excesses up to 99%. In the part of experimental materials, we found many familiar compounds, such as 4-Acetylpyridine(cas: 1122-54-9COA of Formula: C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.COA of Formula: C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Chiral Imidazo[1,5-a]pyridine-Oxazolines: A Versatile Family of NHC Ligands for the Highly Enantioselective Hydrosilylation of Ketones》 was published in Organometallics in 2020. These research results belong to Chinna Ayya, Swamy .P.; Varenikov, Andrii; de Ruiter, Graham. SDS of cas: 1122-54-9 The article mentions the following:

Herein the authors report the synthesis and application of a versatile class of N-heterocyclic carbene ligands based on an imidazo[1,5-a]pyridine-3-ylidine backbone that is fused to a chiral oxazoline auxiliary. The key step in the synthesis of these ligands involves the installation of the oxazoline functionality via a microwave-assisted condensation of a cyano-azolium salt with a wide variety of 2-amino alcs. The resulting chiral bidentate NHC-oxazoline ligands form stable complexes with Rh(I) that are efficient catalysts for the enantioselective hydrosilylation of structurally diverse ketones. The corresponding secondary alcs. are isolated in good yields (typically >90%) with good to excellent enantioselectivities (80-95% ee). The reported hydrosilylation occurs at ambient temperatures (40°), with excellent functional group tolerability. Even ketones bearing heterocyclic substituents (e.g., pyridine or thiophene) or complex organic architectures are hydrosilylated efficiently, which is discussed further. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9SDS of cas: 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. SDS of cas: 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《CuO grafted triazine functionalized covalent organic framework as an efficient catalyst for C-C homo coupling reaction》 was published in Molecular Catalysis in 2020. These research results belong to Das, Sabuj Kanti; Krishna Chandra, Bijan; Molla, Rostam A.; Sengupta, Manideepa; Islam, Sk. Manirul; Majee, Adinath; Bhaumik, Asim. Synthetic Route of C5H6BNO2 The article mentions the following:

A new copper oxide immobilized covalent organic framework (COF) material CuII-TRIPTA by grafting of CuO nanoparticles at the surface of a nitrogen rich porous COF material TRIPTA was reported. TRIPTA was synthesized through the extended Schiff base reaction between 2,4,6-triformylphloroglucinol and 1,3,5-tris-(4-aminophenyl)triazine. The COF as well as CuO loaded materials were characterized by powder X-ray diffraction (PXRD), transmission electron microscopy (TEM), XPS, N2 adsorption-desorption, Fourier transform IR spectroscopy (FT-IR), thermogravimetry (TG) and EPR spectroscopic analyses. CuII-TRIPTA material was successfully applied as heterogeneous nanocatalyst for the C-C homo-coupling reaction of phenylboronic acids to synthesize wide range of biaryl compounds under mild and eco-friendly conditions (60°, methanol solvent). Remarkably high sp. surface area of CuII-TRIPTA (583 m2 g-1) and highly accessible catalytic sites in the 2D-hexagonal COF nano-architecture potentially makes it excellent catalyst in the C-C bond formation reaction, which was evident from the high TON of the catalyst in this reaction. The catalyst was recollected and reused till 6th cycles without any noticeable change of its catalytic activity, suggesting its high catalytic efficiency in this C-C bond formation reaction. The experimental process involved the reaction of 2-Pyridinylboronic acid(cas: 197958-29-5Synthetic Route of C5H6BNO2)

2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Synthetic Route of C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem