Hu, Huifen’s team published research in Inorganic Chemistry Communications in 2020 | CAS: 98-98-6

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Name: Picolinic acid

《A novel 1-D chain organic-inorganic hybrid CuII-PrIII heterometallic germanomolybdate decorated by 2-picolinic acid ligands》 was published in Inorganic Chemistry Communications in 2020. These research results belong to Hu, Huifen; Cui, Limin; Liu, Mengling; Yang, Gengxu; Chen, Lijuan. Name: Picolinic acid The article mentions the following:

A novel 1-dimensional chain organic-inorganic hybrid CuII-PrIII heterometallic germanomolybdate decorated by 2-picolinic acid ligands [NH4]2[Pr(H2O)5]2[Cu(pic)2]2[Cu(pic)2(H2O)2]3[α- GeMo12O40]2·24H2O (1) [Hpic = 2-picolinic acid] was obtained via the strategy of combining in-situ assembly reaction and stepwise synthesis in aqueous solution and structurally characterized by IR spectra, elemental analyses, single-crystal x-ray diffraction, and TGA. It should be pointed out that the polyoxoanion unit of 1 consists of two plenary Keggin [α-GeMo12O40]4- anion and an organic-inorganic hybrid 3d-4f heterometallic {[Pr(H2O)5]2[Cu(pic)2]2[Cu(pic)2(H2O)2]3}6+ segment and neighboring polyoxoanion units are further expanded into a 1-dimensional chain alignment by virtue of {Cu(pic)2} linkers. Also, the absorption properties of 1 toward the cationic dye methylene blue (MB) in water solution were studied in detail, which shows a good absorption capacity toward the dye in aqueous solution and the absorption kinetic conforms to the 2nd-order kinetic model. The experimental process involved the reaction of Picolinic acid(cas: 98-98-6Name: Picolinic acid)

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Name: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Wu, Fengtian’s team published research in Letters in Organic Chemistry in 2020 | CAS: 197958-29-5

2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: pyridine-derivatives

《2,5-Dihydroxyterephthalic Acid Accelerated Cu(NO3)2.3H2O-Catalyzed Homocoupling Reaction of Arylboronic Acids》 was published in Letters in Organic Chemistry in 2020. These research results belong to Wu, Fengtian; Nan, Chenlong; Xie, Jianwei; Ma, Mingyang. Category: pyridine-derivatives The article mentions the following:

A catalyst system derived from com. available Cu(NO3)2.3H2O and 2,5-dihydroxyterephthalic acid is applied to the homocoupling reaction of arylboronic acids. This transformation provides a convenient approach to sym. biaryls with good to excellent yields (39%- 95%), and exhibits good functional group compatibility. Furthermore, biaryl can be prepared in gram quantities in good yield. In the experimental materials used by the author, we found 2-Pyridinylboronic acid(cas: 197958-29-5Category: pyridine-derivatives)

2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ji, Yun-Xing’s team published research in Advanced Synthesis & Catalysis in 2020 | CAS: 2510-22-7

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Recommanded Product: 2510-22-7

《Intermolecular Iodofluoroalkylation of Unactivated Alkynes and Alkenes Mediated by Manganese Catalysts》 was written by Ji, Yun-Xing; Wang, Lu-Jun; Guo, Wei-Si; Bi, Qirui; Zhang, Bo. Recommanded Product: 2510-22-7 And the article was included in Advanced Synthesis & Catalysis in 2020. The article conveys some information:

An approach for iodofluoroalkylation of unactivated alkynes and alkenes facilitated by an earth-abundant and inexpensive manganese catalyst, Mn2(CO)10, is reported. This protocol employs visible light as the energy input and shows a wide substrate scope and high functional-group compatibility. A variety of synthetically useful fluoroalkylated alkyl and alkenyl iodides can be prepared in moderate to excellent yields. The reaction features high efficiency, operational simplicity, scalability, as well as excellent chemo-, regio-, and E/Z selectivities.4-Ethynylpyridine(cas: 2510-22-7Recommanded Product: 2510-22-7) was used in this study.

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Recommanded Product: 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chen, Jun’s team published research in Journal of Inorganic Biochemistry in 2020 | CAS: 1134-35-6

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.SDS of cas: 1134-35-6 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

《A lysosome-targeted ruthenium(II) polypyridyl complex as photodynamic anticancer agent》 was written by Chen, Jun; Tao, Qin; Wu, Jian; Wang, Mengmeng; Su, Zhi; Qian, Yong; Yu, Tao; Wang, Yan; Xue, Xuling; Liu, Hong-Ke. SDS of cas: 1134-35-6 And the article was included in Journal of Inorganic Biochemistry in 2020. The article conveys some information:

Polypyridyl ruthenium complexes as novel photosensitizers had drawn attention due to its high selectivity towards cancer cells and low toxicity to normal cells. Herein, we synthesized a lysosome-targeted polypyridyl ruthenium complex Rhein-Ru(bpy)3 (bpy = 2,2′-bipyridine, rhein = 4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid), tethering with the Chinese medicine herb rhein. Rhein-Ru(bpy)3 exhibited high phototoxicity with short time of irradiation against tumor cell lines with the IC50 value of 2.4- 8.7 μM, and higher cytotoxicity against cisplatin-resistant A2780 cell lines, suggesting that Rhein-Ru(bpy)3 could overcome the cisplatin resistance. Moreover, Rhein-Ru(bpy)3 displayed low cytotoxicity towards cell lines in dark incubation, which was beneficial to reduce the toxic side effects towards normal cell lines. Besides, the confocal imaging and western blotting assay results suggested that Rhein-Ru(bpy)3 could induce cancer cell death through the autophagy pathway. These results inspired us that lysosome-targeted photosensitizers based on ruthenium complexes showed great potential for photodynamic therapy (PDT) application in cancer treatment. In addition to this study using 4,4′-Dimethyl-2,2′-bipyridine, there are many other studies that have used 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6SDS of cas: 1134-35-6) was used in this study.

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.SDS of cas: 1134-35-6 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dey, Ananta’s team published research in Journal of Physical Chemistry B in 2020 | CAS: 1134-35-6

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.Computed Properties of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.

《Proton-Coupled Electron Transfer for Photoinduced Generation of Two-Electron Reduced Species of Quinone》 was written by Dey, Ananta; Ghorai, Nandan; Das, Amitava; Ghosh, Hirendra N.. Computed Properties of C12H12N2 And the article was included in Journal of Physical Chemistry B in 2020. The article conveys some information:

Purpose-built mols. that follow the fundamental process of photosynthesis have significance in developing better insight into the natural photosynthesis process. Quinones have a significant role as electron acceptors in natural photosynthesis, and their reduction is assisted through H-bond donation or protonation. The major challenge in such studies is to couple the multielectron and proton-transfer process and to achieve a reasonably stable charge-separated state for the elucidation of the mechanistic pathway. We have tried to address this issue through the design of a donor-acceptor-donor mol. triad (2RuAQ) derived from two equivalent [Ru(bpy)3]2+ derivatives and a bridging anthraquinone moiety (AQ). Photoinduced proton-coupled electron transfer (PCET) for this mol. triad was systematically investigated in the absence and presence of hexafluoroisopropanol and p-toluenesulfonic acid (PTSA) using time-resolved absorption spectroscopy in the ultrafast time domain. Results reveal the generation of a relatively long-lived charge-separated state in this multi-electron transfer reaction, and we could confirm the generation of AQ2- and RuIII as the transient intermediates. We could rationalize the mechanistic pathway and the dynamics associated with photoinduced processes and the role of H-bonding in stabilizing charge-separated states. Transient absorption spectroscopic studies reveal that the rates of intramol. electron transfer and the mechanistic pathways associated with the PCET process are significantly different in different solvent compositions having different polarities. In acetonitrile, a concerted PCET mechanism prevails, whereas the stepwise PCET reaction process is observed in the presence of PTSA. The results of the present study represent a unique model for the mechanistic diversity of PCET reactions.4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Computed Properties of C12H12N2) was used in this study.

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.Computed Properties of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Senthil Kannan, K.’s team published research in AIP Conference Proceedings in 2020 | CAS: 98-98-6

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Recommanded Product: Picolinic acid

《Growth and characterization of picolinium maleate (PM) crystals》 was written by Senthil Kannan, K.; Venkatachalam, K.; Bhakya, K.; Sharmidha, B.; Kalaivani, M.; Devi, S. Gayathri. Recommanded Product: Picolinic acid And the article was included in AIP Conference Proceedings in 2020. The article conveys some information:

Picolinium Maleate crystals are of NLO type and are having extensive range of employing in opto-electronic and frequency doubling and which have Empirical formula as C10H9NO6, these crystal belongs to monoclinic system, with space group as P21/c and at. grid scaling are a=14.650Å, b=10.398Å, c=6.908Å, α=γ=90°, β=100° and crystallite size is 0.25*0.16*0.25 mm3. As the crystals of PM are of NLO of the second order, it can be used for bio applications and here used for anti-diabetic (AD) activities and filter usefulness exptl. (c) 2020 American Institute of Physics. In the experimental materials used by the author, we found Picolinic acid(cas: 98-98-6Recommanded Product: Picolinic acid)

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Recommanded Product: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lee, So Jeong’s team published research in Journal of Organic Chemistry in 2021 | CAS: 53939-30-3

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Recommanded Product: 53939-30-3

Lee, So Jeong; Morales-Colon, Maria T.; Brooks, Allen F.; Wright, Jay S.; Makaravage, Katarina J.; Scott, Peter J. H.; Sanford, Melanie S. published their research in Journal of Organic Chemistry in 2021. The article was titled 《SNAr Radiofluorination with In-Situ Generated [18F]Tetramethylammonium Fluoride》.Recommanded Product: 53939-30-3 The article contains the following contents:

This report described a method for the nucleophilic radiofluorination of (hetero)aryl chlorides, (hetero)aryl triflates, and nitroarenes using a combination of [18F]KF·K2.2.2 and Me4NHCO3 for the in-situ formation of a strongly nucleophilic fluorinating reagent (proposed to be [18F]Me4NF). This method was applied to 24 substrates bearing diverse functional groups, and it generates [18F](hetero)aryl fluoride products in good to excellent radiochem. yields in the presence of ambient air/moisture. The reaction was applied to the preparation of 18F-labeled HQ-415 for potential (pre)clin. use. In the part of experimental materials, we found many familiar compounds, such as 5-Bromo-2-chloropyridine(cas: 53939-30-3Recommanded Product: 53939-30-3)

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Recommanded Product: 53939-30-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ahmad, Gulraiz’s team published research in Arabian Journal of Chemistry in 2021 | CAS: 1692-25-7

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Synthetic Route of C5H6BNO2

Ahmad, Gulraiz; Rasool, Nasir; Qamar, Muhammad Usman; Alam, Mohammed Mujahid; Kosar, Naveen; Mahmood, Tariq; Imran, Muhammad published their research in Arabian Journal of Chemistry in 2021. The article was titled 《Facile synthesis of 4-aryl-N-(5-methyl-1H-pyrazol-3-yl)benzamides via Suzuki Miyaura reaction: Antibacterial activity against clinically isolated NDM-1-positive bacteria and their Docking Studies》.Synthetic Route of C5H6BNO2 The article contains the following contents:

The production of new pyrazole amide derivatives I (Ar = 4-AcC6H4, 4-ClC6H4, 4-MeOC6H4, etc.) and their potential against New Delhi metallo-β-lactamase-1 (NDM-1) producing bacteria was described in the present manuscript. The 4-bromo-N-(5-methyl-1H-pyrazol-3-yl)benzamide was synthesized via direct amidation of protected 5-methyl-1H-pyrazol-3-amine. The target pyrazole amide derivatives I were synthesized in moderate to excellent yield via Palladium catalyzed Suzuki cross-coupling of intermediate mol. with different aryl and heteroaryl boronic acids. The in vitro antibacterial effect against NDM-1-pos. Acinetobacter baumannii and Klebsiella pneumoniae of newly synthesized analogs I were determined by Agar well diffusion method. Moreover, MIC and MBC values were also evaluated against the tested bacteria. In addition, the Mol. Docking study of pyrazole amide derivatives I against the NDM producing A. baumannii was performed to investigate the intermol. interaction. The binding affinity and their values were compared with L-captopril. The I (Ar = 3-ClC6H4) had greatest potential value and was appeared as a promising antibacterial agent.Pyridin-3-ylboronic acid(cas: 1692-25-7Synthetic Route of C5H6BNO2) was used in this study.

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Synthetic Route of C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bagherzadeh, Nastaran’s team published research in Molecular Catalysis in 2021 | CAS: 197958-29-5

2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Formula: C5H6BNO2

Bagherzadeh, Nastaran; Sardarian, Ali Reza; Eslahi, Hassan published their research in Molecular Catalysis in 2021. The article was titled 《Sustainable and recyclable magnetic nanocatalyst of 1,10-phenanthroline Pd(0) complex in green synthesis of biaryls and tetrazoles using arylboronic acids as versatile substrates》.Formula: C5H6BNO2 The article contains the following contents:

A magnetic nanocatalyst was purveyed as a heterogeneous recoverable palladium-based catalyst anchored on green, sustainable and phosphine free support. Resulted Fe3O4@SiO2-Phen-Pd(0) nanocatalyst bearing powerful phenanthroline ligand was thoroughly characterized by physicochem. approaches like UV-vis, FT-IR, EDX, XRD, TGA, ICP, VSM, DLS, FESEM, and TEM analyses. After finding trustable data, the obtained magnetic catalyst was considered to be applied in the Suzuki-Miyaura type C-C couplings and getting corresponding tetrazoles using arylboronic acid derivatives as alternate precursors of aromatic halides and stupendous data were observed The results came from multiple reactions, including the reaction of 2-Pyridinylboronic acid(cas: 197958-29-5Formula: C5H6BNO2)

2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Formula: C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lu, Ru-Qiang’s team published research in Chemistry – A European Journal in 2021 | CAS: 1692-25-7

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: Pyridin-3-ylboronic acid

Lu, Ru-Qiang; Zhuo, You-Zhen; Bao, Yue-Hua; Yang, Lin-Lin; Qu, Hang; Tang, Xiao; Wang, Xin-Chang; Li, Zhi-Hao; Cao, Xiao-Yu published their research in Chemistry – A European Journal in 2021. The article was titled 《Cyclopentadienone Derivative Dimers as Tunable Photoswitches》.Recommanded Product: Pyridin-3-ylboronic acid The article contains the following contents:

A series of photoswitchable cyclopentadienone derivative dimers bearing bromo, thienyl, 4-(dimethylamino)phenyl, 3-pyridinyl, 4-nitrophenyl and cyano groups was designed and facilely synthesized. Photoswitching properties such as the photoconversions in the photostationary state (PSS), the thermal kinetics and thermal half-lives of photoisomers were systematically studied. These photoswitches show high fatigue resistance and large photoconversions in the PSS. This work proves that the photoswitching properties of photoswitches based on cyclopentadienone dimers can be tuned by substitution groups and also pave the way to functionalize the cyclopentadienone derivative dimer-based photoswitch, which is important for its future applications. The results came from multiple reactions, including the reaction of Pyridin-3-ylboronic acid(cas: 1692-25-7Recommanded Product: Pyridin-3-ylboronic acid)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Recommanded Product: Pyridin-3-ylboronic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem