Month: November 2022

《Tuning layered superstructures in precision polymers》 was published in Scientific Reports in 2020. These research results belong to Danke, Varun; Reimann, Sophie; Binder, Wolfgang H.; Gupta, Gaurav; Beiner, Mario. Product Details of 141-86-6 The article mentions the following:

An approach to influence and control layered superstructures by varying the methylene sequence length between two consecutive functional groups in linear precision polymers containing 2,6-diaminopyridine (DAP) groups is presented. Layered superstructures with repeating units involving three monomeric units along the chain direction with very high coherence lengths upto 110 nm are observed in case of shorter alkyl segments, (16 and 18 CH2 units), while more conventional layer superstructures incorporating only one monomer are found for related polymers with 20 CH2 units per methylene sequence. A building block model explaining the unusually large periodicity of three monomeric units is proposed wherein layers containing crystalline or amorphous methylene sequences occur in different combinations. Occurrence of different layered structures depending on crystallization conditions, methylene sequence length as well as functional group type is explained by a competition of H-interactions between the DAP groups and the van der Waal forces between the hydrophobic methylene groups. In the experimental materials used by the author, we found 2,6-Diaminopyridine(cas: 141-86-6Product Details of 141-86-6)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Product Details of 141-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Asymmetrically difunctionalized dibenzo[b,d]furan-based hole blocking materials for high-performance blue phosphorescent organic light-emitting diodes》 was published in Dyes and Pigments in 2020. These research results belong to Hong, Soojin; Chung, Won Jae; Jang, Seokhoon; Yu, Gyeonghwa; Lee, Jun Yeob; Lee, Youngu. Category: pyridine-derivatives The article mentions the following:

Three new hole blocking materials based on asym. difunctionalized dibenzo[b,d]furan, diphenyl(2-(pyridin-3-yl)dibenzo[b,d]furan-6-yl)phosphine oxide (DBFPO-Py), diphenyl(2-(pyrimidin-5-yl)dibenzo[b,d]furan-6-yl)phosphine oxide (DBFPO-Pyr), and diphenyl(2-(4-(triphenylsilyl)phenyl)dibenzo[b,d]furan-6-yl)phosphine oxide (DBFPO-Si) were designed and synthesized for high-performance phosphorescent OLEDs. Phosphine oxide, tetraphenylsilane, pyridine, and pyrimidine segments are introduced into the asym. position of a dibenzo[b,d]furan. DBFPO-Py, DBFPO-Pyr, and DBFPO-Si possess high thermal stability; high triplet energies of 2.96, 2.98, and 2.80 eV; and deep HOMO energy levels of -7.13, -7.23 and -7.07 eV;, resp. Blue phosphorescent OLEDs with DBFPO-Py, DBFPO-Pyr, and DBFPO-Si show low turn-on voltages, high current and power efficiencies, and superior external quantum efficiencies. Blue phosphorescent OLEDs with DBFPO-Py and DBFPO-Pyr showed improved performance in terms of current and power efficiencies, etc., compared with the device with 1,3-bis(3,5-dipyrid-3-yl-phenyl)benzene (BmPyPB), which is commonly used as a hole blocking layer. The blue phosphorescent OLEDs with DBFPO-Pyr showed the best performance with maximum external quantum efficiency of 23.6%, current efficiency of 29.8 cd A-1, power efficiency of 26.0 lm W-1, and low efficiency roll-off of 6.38%. Hole blocking materials based on asym. difunctionalized dibenzo[b,d]furan are expected to make a significant contribution to the development of blue phosphorescent OLEDs. The experimental part of the paper was very detailed, including the reaction process of Pyridin-3-ylboronic acid(cas: 1692-25-7Category: pyridine-derivatives)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Structural isomers of 9-(pyridin-2-yl)-9H-carbazole in combination with 9’H-9,3′:6′,9”-tercarbazole and their application to high efficiency solution processed green TADF OLEDs》 was written by Hwang, Jinhyo; Yoon, Jiwon; Kim, Chae Yeong; Choi, Suna; Kang, Hyunchul; Kim, Jun Yun; Yoon, Dae-Wi; Han, Chang Wook; Park, Sungnam; Cho, Min Ju; Choi, Dong Hoon. Formula: C5H3Br2N And the article was included in Dyes and Pigments in 2020. The article conveys some information:

Two host materials, CzPy2TCz and CzPy3TCz, were designed as structural isomers and synthesized to achieve high efficiency thermally activated delayed fluorescence-organic light emitting diodes (TADF-OLEDs). The design strategy involved introducing a pyridine group into the core structure as an electron-withdrawing unit and varying the substitution position of tercarbazole (TCz). To realize green TADF-OLED, the 2 host materials synthesized in this study have excellent thermal stability and high excited triplet energy (T1 = 2.95-2.98 eV). The maximum external quantum efficiency and current efficiency values for CzPy2TCz were 23.81% and 80.2 cd/A, resp. and the resp. values for CzPy3TCz were 20.27% and 70.1 cd/A, resp. Structural isomers with carbazole (Cz) and TCz units at the 2,6-position of the pyridine core effectuate better device performance. Consequently, the host materials introduced in this study play an important role in implementing high performing solution-processed green TADF-OLED. The experimental process involved the reaction of 2,5-Dibromopyridine(cas: 624-28-2Formula: C5H3Br2N)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Formula: C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Type I photosensitizers based on phosphindole oxide for photodynamic therapy: apoptosis and autophagy induced by endoplasmic reticulum stress》 was written by Zhuang, Zeyan; Dai, Jun; Yu, Maoxing; Li, Jianqing; Shen, Pingchuan; Hu, Rong; Lou, Xiaoding; Zhao, Zujin; Tang, Ben Zhong. HPLC of Formula: 2510-22-7 And the article was included in Chemical Science in 2020. The article conveys some information:

Photodynamic therapy is considered a pioneering and effective modality for cancer treatment, but it is still facing challenges of hypoxic tumors. Recently, Type I PDT, as an effective strategy to address this issue, has drawn considerable attention. Few reports are available on the capability for Type I reactive oxygen species (ROS) generation of purely organic photosensitizers (PSs). Herein, we report two new Type I PSs, α-TPA-PIO and β-TPA-PIO, from phosphindole oxide-based isomers with efficient Type I ROS generation abilities. A detailed study on photophys. and photochem. mechanisms is conducted to shed light on the mol. design of PSs based on the Type I mechanism. The in vitro results demonstrate that these two PSs can selectively accumulate in a neutral lipid region, particularly in the endoplasmic reticulum (ER), of cells and efficiently induce ER-stress mediated apoptosis and autophagy in PDT. In vivo models indicate that β-TPA-PIO successfully achieves remarkable tumor ablation. The ROS-based ER stress triggered by β-TPA-PIO-mediated PDT has high potential as a precursor of the immunostimulatory effect for immunotherapy. This work presents a comprehensive protocol for Type I-based purely organic PSs and highlights the significance of considering the working mechanism in the design of PSs for the optimization of cancer treatment protocols. In the experimental materials used by the author, we found 4-Ethynylpyridine(cas: 2510-22-7HPLC of Formula: 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. HPLC of Formula: 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ma, Cui-Cui; Zhu, Xing-Xing; Liu, Li; Dai, Jian-Jun; Xu, Jun; Xu, Hua-Jian published their research in Tetrahedron Letters in 2021. The article was titled 《Synthesis of polyfluorinated aromatic ethers and thioethers by synergistic cleavage of C-B bond and C-F bond of B(C6F5)3》.Category: pyridine-derivatives The article contains the following contents:

A concise and efficient method for the synthesis of polyfluorinated aromatic ethers 2,3,5,6-F4C6HOR (R = 3-nitrophenyl, 1-naphthyl, quinolin-5-yl, etc.) and thioethers 2,3,5,6-F4C6HSR1 (R1 = benzyl, cyclohexyl, naphth-2-yl, etc.) by synergistic cleavage of C-B bond and C-F bond of B(C6F5)3 is reported. The reaction could proceed smoothly with excellent functional-group compatibility. In addition, the transformation represents the first general application of B(C6F5)3 as reaction partners in cross-coupling reaction. In the experimental materials used by the author, we found 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2Category: pyridine-derivatives)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Panish, Robert; Thieu, Tho; Balsells, Jaume published their research in Organic Letters in 2021. The article was titled 《Copper-Catalyzed Synthesis of 5-Carboxyl-4-perfluoroalkyl Triazoles》.Category: pyridine-derivatives The article contains the following contents:

A facile, scalable synthesis of previously inaccessible trifluoromethyl and perfluoroalkyl triazoles is disclosed. Mediated by copper, this catalytic protocol enables access to 4-perfluoroalkyl triazoles from commodity chems. A catalytic Cu(II) system wherein copper serves two roles (generation of N-tosyl-2-vinyldiazenes and N-N bond formation) allows for rapid assembly of 5-carboxyl-4-perfluoroalkyl-triazoles from N-tosylhydrazide and perfluoroalkyl acetoacetates. Et 4,4,4-trifluoro-3-(2-tosylhydrazineylidene)butanoate, a previously unknown air and bench stable reagent for access to CF3-triazoles, was developed to enable this chem. This led to the identification of a series of crystalline hydrazone reagents that could be used as templates to construct an array of triazoles. Hydrolysis and decarboxylation parlay this approach into a means to access 5-H-4-CF3-triazoles. The approach exhibits high functional group tolerance and can be executed on a multigram scale. In addition to this study using 2-Bromo-5-methylpyridine, there are many other studies that have used 2-Bromo-5-methylpyridine(cas: 3510-66-5Category: pyridine-derivatives) was used in this study.

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ohnishi, Ryuhei; Ohta, Hidetoshi; Mori, Shigeki; Hayashi, Minoru published their research in Organometallics in 2021. The article was titled 《Cationic Dirhodium Complexes Bridged by 2-Phosphinopyridines Having an Exquisitely Positioned Axial Shielding Group: A Molecular Design for Enhancing the Catalytic Activity of the Dirhodium Core》.HPLC of Formula: 626-05-1 The article contains the following contents:

This report describes a strategy to create highly electrophilic dirhodium catalysts. The electrophilicity of lantern-type dirhodium complexes is generally decreased by the coordination of a ligand to the axial site, which often causes a reduction in the catalytic activity. The authors designed and synthesized cationic dirhodium complexes bridged by 2-diarylphosphinopyridines having a bulky 2,4,6-triisopropylphenyl (Tip) group that can prevent the attack of external mols. to the closest axial site. Theor. calculations indicated that the Tip group weakly interacts with the axial site but hardly reduces the electrophilicity of the dirhodium core. The complexes served as excellent catalyst precursors for the dehydrogenative silylation of alcs. using hydrosilanes under mild conditions and a low metal loading, producing the silyl ethers in higher yields in comparison to conventional dirhodium complexes. In the experimental materials used by the author, we found 2,6-Dibromopyridine(cas: 626-05-1HPLC of Formula: 626-05-1)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. HPLC of Formula: 626-05-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Aza-Henry Reaction: Synthesis of Nitronaphthylamines from 2-(Alkynyl)benzonitriles》 was written by Verma, Shalini; Kumar, Manoj; Verma, Akhilesh K.. Reference of 2-Bromonicotinaldehyde And the article was included in Organic Letters in 2020. The article conveys some information:

A transition-metal-free approach for construction of nitronaphthylamines has been developed for the first time through aza-henry, chemoselective, and regioselective annulation of 2-alkynylbenzonitriles with nitromethane. In addition, the strategy provides an elegant, operationally simple and atom-economical route for the synthesis of nitroamino substituted heterocyclic scaffolds, featuring a range of sensitive functional groups. The reaction could also devise acetonitrile and acetophenone as nucleophile. The protocol has been successfully implemented for late-stage modification of bioactive mols.2-Bromonicotinaldehyde(cas: 128071-75-0Reference of 2-Bromonicotinaldehyde) was used in this study.

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Reference of 2-Bromonicotinaldehyde

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ponpao, Nipaphorn; Senapak, Warapong; Saeeng, Rungnapha; Jaratjaroonphong, Jaray; Sirion, Uthaiwan published their research in RSC Advances in 2021. The article was titled 《Metal- and solvent-free synthesis of aniline- and phenol-based triarylmethanes via Bronsted acidic ionic liquid catalyzed Friedel-Crafts reaction》.Synthetic Route of C6H4BrNO The article contains the following contents:

A beneficial, scalable and efficient methodol. for the synthesis of aniline-based triarylmethanes was established through the double Friedel-Crafts reaction of com. aldehydes and primary, secondary or tertiary anilines using Bronsted acidic ionic liquid as a powerful catalyst, namely [bsmim][NTf2] (4-sulfono-1-butylmethylimidazolium trifluoromethanesulfonimide). This protocol was successfully performed under metal- and solvent-free conditions with a broad range of substrates, giving the corresponding aniline-based triarylmethane products in good to excellent yields (up to 99%). In addition, alternative aromatic nucleophiles such as phenols and electron-rich arenes were also studied using this useful approach to achieve a diversity of triarylmethane derivatives in high to excellent yields. The results came from multiple reactions, including the reaction of 2-Bromonicotinaldehyde(cas: 128071-75-0Synthetic Route of C6H4BrNO)

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Synthetic Route of C6H4BrNO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem