Month: November 2022

Liu, Jian-Qiang; Li, Xue-Feng; Gu, Chu-Ying; da Silva, Julio C. S.; Barros, Amanda L.; Alves, Severino Jr.; Li, Bao-Hong; Ren, Fei; Batten, Stuart R.; Soares, Thereza A. published an article in 2015, the title of the article was A combined experimental and computational study of novel nanocage-based metal-organic frameworks for drug delivery.Quality Control of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid And the article contains the following content:

Three new metal organic frameworks (MOFs) with chem. formulas [(CH3)2NH2] [Sm3(L1)2(HCOO)2(DMF)2(H2O)]·2DMF·18H2O (1), [Cu2(L2)(H2O)2]·2.22DMA (2) and [Zn2(L1)(DMA)]·1.75DMA were synthesized and structurally characterized. 1 and 2 show a classical NbO-like topol. and have two types of interconnected cages. 3 exhibits an uncommon zzz topol. and has two types of interconnected cages. These MOFs can adsorb large amounts of the drug 5-fluorouracil (5-FU) and release it in a progressive way. 5-FU was incorporated into desolvated 1, 2 and 3 with loadings of 0.40, 0.42, and 0.45 g g-1, resp. The drug release rates were 72%, 96% and 79% of the drug after 96 h in 1, 120 h in 2 and 96 h in 3, resp. Grand Canonical Monte Carlo (GCMC) simulations were performed to investigate the mol. interactions during 5-FU adsorption to the three novel materials. The GCMC simulations reproduced the exptl. trend with respect to the drug loading capacity of each material. They also provided a structural description of drug packing within the frameworks, helping to explain the load capacity and controlled release characteristics of the materials. 5-FU binding preferences to 1, 2 and 3 reflect the diversity in pore types, chem. and sizes. The calculated drug load is more related to the mol. properties of accessible volume Vacc than to the pore size. The experimental process involved the reaction of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid(cas: 1431292-15-7).Quality Control of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid

The Article related to nanocage metal organic framework preparation 5fu drug delivery cancer, Pharmaceuticals: Formulation and Compounding and other aspects.Quality Control of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xing, Kai; Fan, Rui-Qing; Liu, Xiao-Yuan; Gai, Shuang; Chen, Wei; Yang, Yu-Lin; Li, Jing published an article in 2020, the title of the article was A self-calibrating dual responsive platform for the sensitive detection of sulfite and sulfonic derivatives based on a robust Hf(IV) metal-organic framework.Name: Pyridine-3-sulfonic acid And the article contains the following content:

A robust hafnium-based metal organic framework, Hf-PBTA, with sensitive and self-calibrating dual-emissive fluorescence response towards sulfite and sulfonic derivatives, including antibiotic sulfamethazine, has been developed, which shows fast detection of sulfite ions at a concentration as low as 76 ppb. The opposite response tendency from two radiative pathways towards aromatic sulfonic mols. and sulfite anions stems from the synergistic effect of the pyridine protonation effect, π-π stacking interaction and intramol. twist motion. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Name: Pyridine-3-sulfonic acid

The Article related to fluorescent sensor sulfite sulfonic derivative metal organic framework, Organic Analytical Chemistry: Determinations and other aspects.Name: Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 31, 2011, Murahdharan, Balathandapani; Gopu, Gopalakrishnan; Laya, Saraswathy; Vedhi, Chinnapiyan; Manisankar, Paramasivam published an article.Name: N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate The title of the article was A study on preparation and use of nano poly pyrrole and nano poly (3,4-ethylenedioxythiophene) coated glassy carbon electrode for the determination of antihistamine in pharmaceutical and urine sample. And the article contained the following:

Pheniramine maleate (PA), an antihistamine, was determined by Differential Pulse Stripping voltammetry using nano polypyrrole (Ppy) and nano poly (3,4-ethylenedioxythiophene) (PEDOT) modified glassy carbon electrodes. The cyclic voltammetric behavior of pheniramine was studied in aqueous acidic, neutral and alk. conditions. One well-defined oxidation peak was observed in the cyclic voltammograms at all pHs. The influence of pH, scan rate and concentration revealed irreversible electron transfer and the oxidation was diffusion controlled adsorption. The SEM anal. confirmed good accumulation of PA on the electrode surface. A systematic study of influence of various exptl. parameters that affect the stripping voltammetric response was carried out and the maximum peak current conditions were arrived at. Calibration was made under maximum peak current conditions. The range of study was 0.05 to 0.4 μg/mL on Ppy/GCE and 0.025 to 0.4 μg/mL on PEDOT/GCE and the lower limit of determination were 0.035 μg/mL on Ppy/GCE and 0.016 μg/mL on PEDOT/GCE. The suitability of the method for the determination of PA in pharmaceutical preparations and urine samples was also ascertained. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Name: N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate

The Article related to polypyrrole ethylenedioxythiophene glassy carbon electrode nanoparticle antihistamine pheniramine maleate, Pharmacology: Drug Interactions and General Pharmacology and other aspects.Name: N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On April 12, 2019, Wu, Fengshou; Yue, Liangliang; Zhu, Sizhe; Wang, Kai; Sun, Qi published a patent.Quality Control of [2,2′-Bipyridine]-3,3′-diamine The title of the patent was Preparation method of metal ruthenium nano material, and its application as antitumor drug. And the patent contained the following:

The preparation method of metal ruthenium nano material includes (1) preparing metal ruthenium coordination compound by using amino-containing polypyridine ligands (5-amino-1,10-phenanthroline, 2-amino-1,10-phenanthroline, etc.) and ruthenium trichloride, dissolving in citric acid solution, malic acid solution or oxalic acid solution, and ultrasonically dispersing for 10-40 min to obtain mixture A; (2) heating at 140-220°C for 1-5 h to obtain mixture B; (3) adjusting pH to 6.8-7.4 with alk. reagent, dialyzing for 2-48 h, collecting dialyzate, and freeze drying to obtain final product. The metal ruthenium nano material can be used to prepare antitumor drug. The ruthenium nano material has good water solubility, strong light stability, high fluorescence quantum yield, good photodynamic therapy effect for tumors, and good biocompatibility. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Quality Control of [2,2′-Bipyridine]-3,3′-diamine

The Article related to ruthenium nano material preparation antitumor drug, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Quality Control of [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Liu, Jinjian; Li, Jing; Lu, Wenbo published an article in 2019, the title of the article was Effect of counter cations on the photochromic behaviors of three Zn-viologen complexes.Category: pyridine-derivatives And the article contains the following content:

To determine the influence of counter cations on the photochromic properties of viologen-based compounds, with the self-assembly reaction of different viologen cations (MV2+ = 1,1′-bis(methyl)-4,4′-bipyridinium dication, EV2+ = 1,1′-bis(ethyl)-4,4′-bipyridinium dication, PV2+ = 1,1′-bis(propyl)-4,4′-bipyridinium dication), Zn2+ and H3BTC (1,3,5-benzenetricarboxylic acid), three complexes (MV)0.5[Zn(BTC)(H2O)5]·2H2O (1), (EV)0.5[Zn(BTC)(H2O)5]·H2O (2), and (PV)0.5[Zn(BTC)(H2O)5]·H2O (3) have been synthesized and structurally characterized. The photochromic behavior of the three compounds has been investigated due to the presence of electron-deficient viologen fractions. Compounds 1-3 feature similar isolated structures and all exhibit electron-transfer (ET) photochromism, which can be fine-tuned by introducing different counter cations. The experimental process involved the reaction of 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide(cas: 52243-87-5).Category: pyridine-derivatives

The Article related to zinc viologen complex preparation structure photochromic property, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On June 22, 2018, Han, Zhengbo; Zhao, Siyu published a patent.Application In Synthesis of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid The title of the patent was Preparation method of indium-based metal organic anion framework material and its application in adsorption of cationic organic dye. And the patent contained the following:

The title preparation method includes (1) mixing indium nitrate, 5,5′-(pyridyl-2,5-disubstituted)-1,3-phthalic acid (H4L), N,N-dimethylformamide and nitric acid, and stirring; and (2) reacting at 353-363 K for 3 d, cooling, standing for at least 1 d, washing with N,N-dimethylformamide, filtering, and drying to obtain the final metal organic anion framework material. The material can be used in adsorption of cationic organic dyes such as methylene blue. The experimental process involved the reaction of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid(cas: 1431292-15-7).Application In Synthesis of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid

The Article related to indium pyridyl phthalate mof preparation crystal structure dye adsorption, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Application In Synthesis of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On June 28, 2019, Liu, Jinjian; Li, Jing published a patent.COA of Formula: C16H22Br2N2 The title of the patent was Two photochromic purpurine host-object MOFs material, and its preparation method and application. And the patent contained the following:

The inventive purpurine host-object MOFs material has formula of (EV)2/n[Cd(BTC)(H2O)]n·2nH2O or (PV)2/n[Cd(BTC)(H2O)]n·2nH2O, wherein EV2+ is 1,1-di(ethyl)-4,4-bipyridyl cation, and PV2+ is 1,1-di(propyl)-4,4-bipyridyl cation. One preparation method includes (1) adding 4,4-bipyridine and Et bromide in anhydrous acetonitrile, heating under reflux for 24 h, cooling, filtering, and washing to obtain 1,1-di(ethyl)-4,4-bipyridyl bromide; (2) dissolving with cadmium nitrate in deionized water; (3) dissolving 1,3,5-trimesic acid and NaOH in deionized water under heating; (4) mixing with solution of step (2), standing for 5 d, washing, and drying. The invention is simple and easy to operate, economical and non-toxic. The experimental process involved the reaction of 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide(cas: 52243-87-5).COA of Formula: C16H22Br2N2

The Article related to bipyridinium cadmium trimesate mof preparation crystal structure photochromism, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.COA of Formula: C16H22Br2N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 31, 1992, Cotton, F. Albert; Daniels, Lee M.; Murillo, Carlos A. published an article.Synthetic Route of 636-73-7 The title of the article was Synthesis and x-ray structure of two relatively air-stable chromium(II) 3-pyridinesulfonate compounds. And the article contained the following:

[Cr(pySO3)2(H2O)2]n (I; pySO3H = 3-pyridinesulfonic acid) and Cr(pySO3)2(py)4 (II) were prepared and crystal structures determined I crystallizes as monoclinic, space group P21/c in an extended structure, a 7.723(1), b 12.995(4), c 7.276(3) Å, β 100.24(2)°, Z = 2, R = 0.032, Rw = 0.046. II possesses a mol. structure and crystallizes as monoclinic, space group C2/c, a 17.084(4), b 11.031(3), c 17.828(7) Å, β 112.02(2)°, Z = 4, R = 0.031, Rw = 0.043. The coordination about the Cr atoms is, in both cases, highly distorted. Both compounds are relatively stable towards O in the solid state, especially I. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Synthetic Route of 636-73-7

The Article related to crystal structure chromium pyridinesulfonato complex, sulfonato pyridine chromium complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Synthetic Route of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hurley, Nicholas J.; Rawson, Jeremy M.; Pilkington, Melanie published an article in 2015, the title of the article was 3,3′-Di(pyrazinamoyl)-2,2′-bipyridine: rational ligand design for the self-assembly of a 1-D coordination polymer.Recommanded Product: 75449-26-2 And the article contains the following content:

A new ligand, 3,3′-di(pyrazinamoyl)-2,2′-bipyridine, L3H2 was prepared and is comprised of distinct binding domains capable of facilitating the formation of coordination polymers. Reaction of L3H2 with [Cu2(OAc)4(H2O)2] in the presence of Et3N·HCl affords {[Cu3(L3)(Cl)(OAc)3]·H2O·MeOH}n (1) in which the [L3]2- anion binds two unique copper ions in a bis-tridentate fashion via amide and pyridyl N atoms. This bimetallic unit is linked to an equivalent unit via a pair of 1,3-acetato and μ-chloro bridges to afford a tetrameric [Cu4(L3)2Cl2(OAc)2] core. Coordination of one of the pyrazole substituents from each ligand to a third copper center of a rigid paddlewheel [Cu2(OAc)4] unit leads to a unique 1-dimensional polymeric structure. Magnetic studies of 1 reveal that the magnetism can be described in terms of two sets of exchange interactions; strong antiferromagnetic interactions between the two copper centers within the paddle-wheel (J/k = -190 K) and a combination of weaker ferro- and antiferro-magnetic interactions within the tetrameric core (J’/k = -5.7 K and J”/k = +2.1 K). The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Recommanded Product: 75449-26-2

The Article related to copper bipyridinebisamidopyrazine acetato complex preparation crystal structure magnetism, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Recommanded Product: 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jia, Jing-jing; Zhang, Ling-kai; Li, Shi-xiong; Jiang, Yi-min; Pei, Luo; Yin, Xiu-ju; Liao, Bei-ling published an article in 2017, the title of the article was Synthesis, structure and magnetic analysis of the cobalt polymer based on N-[(3-pyridine)-sulfonyl]aspartate.Recommanded Product: Pyridine-3-sulfonic acid And the article contains the following content:

One new cobalt polymer [Co(L)·3H2O]n (1, H2L = N-[(3-pyridine)-sulfonyl]aspartate) has been synthesized and characterized by single-crystal x-ray diffraction and elemental anal. Polymer 1 belongs to the monoclinic system, space group P21/n with a = 11.479(2), b = 7.3180(15), c = 16.424(3) Å, β = 109.56(3) °, V = 1300.1(5) Å3, Mr = 385.22, Z = 12, F(000) = 790, S = 1.054, R = 0.0670, wR = 0.1147,(Δρ)max = 1.158 and (Δρ)min = -0.754 e/Å3. TGA showed that the polymer first lost one coordinated water mol. and then another two coordinated water mols. The values of the Curie and Curie-Weiss constants of polymer 1 are Cm = 2.67 cm3 mol-1 K and θ = -21.66 K. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Recommanded Product: Pyridine-3-sulfonic acid

The Article related to cobalt pyridinesulfonylaspartate coordination polymer preparation crystal mol structure magnetic, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Recommanded Product: Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem