Month: November 2022

On July 25, 1994, Hurh, Byungserk; Tamane, Tsuneo; Nagasawa, Toru published an article.Product Details of 636-73-7 The title of the article was Purification and characterization of nicotinic acid dehydrogenase from Pseudomonas fluorescens TN5. And the article contained the following:

Membrane-bound nicotinic acid dehydrogenase, an enzyme that catalyzes the formation of 6-hydroxynicotinic acid from nicotinic acid, was solubilized with Triton X-100, and then purified 126-fold with an 11.1% overall recovery from nicotinic acid-induced cells of Pseudomonas fluorescens TN5. The purified enzyme appeared to be homogeneous from anal. by polyacrylamide gel electrophoresis. The enzyme had a mol. mass of approx. 80 kDa and consisted of one subunit. Some electron acceptors, such as phenazine methosulfate, K3Fe(CN)6 and nitro blue tetrazolium, acted as electron acceptors. The purified enzyme catalyzed the hydroxylation of nicotinic acid to 6-hydroxynicotinic acid at a rate of 672 μmol min-1 mg-1 of protein at 35°. It also catalyzed the hydroxylation of pyrazinecarboxylic acid, 3-pyridinesulfonic acid, and 3-cyanopyridine. The purified enzyme exhibited an optimum pH of 8.3, and was sensitive to thiol reagents such as HgCl2 and p-chloromercuribenzoate. A reduction in the amount of the cytochrome c-like component in the respiratory particles was observed during the hydroxylation reaction of nicotinic acid. Thus, nicotinic acid dehydrogenase appeared to be linked to the cytochrome respiratory chain in the cells of P. fluorescens TN5. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Product Details of 636-73-7

The Article related to pseudomonas nicotinate dehydrogenase, respiratory chain coupling nicotinate dehydrogenase pseudomonas, Enzymes: Separation-Purification-General Characterization and other aspects.Product Details of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On January 31, 2011, Guo, Peng; Wang, Jing; Wang, Gang; Li, Shen-jie; Huang, Wen-zhi; Lin, Yu-han; Xu, Guo-hai; Pan, Dao-cheng published an article.Safety of Pyridine-3-sulfonic acid The title of the article was Two three-dimensional pillar-layer AgI-frameworks with helical arrays containing hexamine. And the article contained the following:

Two three-dimensional pillar-layer AgI-frameworks with helical arrays were synthesized at room temperature Compound 1, {[Ag2(H2O)(L2)2L1]·H2O}n (L1 = hexamethylenetetramine, HL2 = 3-pyridinesulfonic acid), is constructed from two-dimensional (6,3) layers which are braced by helical arrays; compound 2, {[Ag3(L1)2(L3)]·6H2O}n (H3L3 = citric acid), is created by two-dimensional layers which are made up of the mix-helical arrays and further pillared by L3 anions and Ag ions. Compounds 1 and 2 were characterized by single-crystal x-ray structure determination, powder X-ray diffraction, IR and TGA. Also, the water and methanol adsorption isotherms for compound 1 were studied. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Safety of Pyridine-3-sulfonic acid

The Article related to silver hexamethylenetetramine pyridinesulfonate citrate polymeric complex preparation crystal structure, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Safety of Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 31, 2002, Rice, Craig R.; Onions, Stuart; Vidal, Natalia; Wallis, John D.; Senna, Maria-Cristina; Pilkington, Melanie; Stoeckli-Evans, Helen published an article.Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine The title of the article was The coordination chemistry of 3,3′-diamino-2,2′-bipyridine and its dication: Exploring the role of the amino groups by X-ray crystallography. And the article contained the following:

The synthesis and structural chem. of new divalent transition metal complexes of the bis-bidentate ligand 3,3′-diamino-2,2′-bipyridine (L1) and its dication L1H2 are described. Ligand L1 reacts with salts of divalent transition metals (Cu(II), Mn(II) and Zn) to afford the (1:1) metal-ligand complexes (2a-2d) as well as the tris complexes (3a-3f). All complexes were fully characterized by spectroscopic methods and the following compounds [Cu(L1)Cl2]2 (2a), [Cu(L1)(OAc)2] (2b), [Zn(L1)3][OTf]2 (3a), and [Zn(L1)3][ZnCl4] (3e and 3f) were structurally characterized. Results from single crystal x-ray diffraction measurements indicate that formation of an intramol. H bond between the two amino groups allows the ligand to coordinate divalent metal ions through their diimine binding sites. Also, the structure of compound 2a reveals that it crystallizes as a dimer in which each Cu ion is bound to two pyridine N atoms and two chloride ions in a distorted square planar arrangement, with a long axial contact from a neighboring amino group completing the approx. square-pyramidal geometry at CuII. Complexation of this ligand in acidic conditions afforded [Cu(L1H2)Cl4] (4), as well as the two salts [L1H2][CuCl4] (5a) and [L1H2][ZnCl4] (5b). All three compounds were structurally characterized and the dication (L1H2) displays a different coordination preference for the chelation of metal ions. In all three cases, both of the heterocyclic N atoms of the ligand are protonated, thus preventing chelation to the metal ion, although for compound 4 crystallog. studies reveal that the two amino functionalities coordinate the Cu(II) ion. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine

The Article related to transition metal aminobipyridine preparation structure, crystal structure transition metal aminobipyridine, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Li; Yue, Jun-Ming; Qiao, Yong-Zhen; Niu, Yun-Yin; Hou, Hong-Wei published an article in 2013, the title of the article was The side chain template effect in viologen on the formation of polypseudorotaxane architecture. Six novel metal coordination polymers and their properties.Name: 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide And the article contains the following content:

The reaction of CuSCN (or CuCl2) in the presence of excess KSCN directed by viologen-based linear templates in a DMF-methanol system affords six coordination polymers, {(MV)[Cu2(SCN)4]}n (1, MV2+ = 1,1′-dimethyl-4,4′-bipyridinium), {(PrV)[Cu2(SCN)4]}n (2, PrV2+ = 1,1′-dipropyl-4,4′-bipyridinium), {(iPV)[Cu2(SCN)4]}n (3, iPV2+ = 1,1′-diisopropyl-4,4′-bipyridinium), [(1-iBV)Cu2(SCN)3]n (4, 1-iBV2+ = 1-isobutyl-4,4′-bipyridinium), {(iBV)[Cu2(SCN)4]}n (5, iBV2+ = 1,1′-diisobutyl-4,4′-bipyridinium), and {(PtV)[Cu2(SCN)4]}n (6, PtV2+ = 1,1′-dipentyl-4,4′-bipyridinium). The [Cu2(SCN)4]n anion in compounds 1, 3, and 5 adopts an infinite 2D polypseudorotaxane architecture and proved effectively that the stoppers at the end can enhance the polyrotaxane formation in the crystalline state, whereas the anion moieties in compounds 2 and 6 exhibit 1D linear architectures, suggesting dethreading from envelopes once solidifying from solution phase. Compound 4 was found to be a 2D coordination polymer with the organic ligand carrying a single charge. The side chain template effect of substituted group, UV-Vis diffuse reflectance spectra in the solid state and TGA properties of the six complexes are investigated. The experimental process involved the reaction of 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide(cas: 52243-87-5).Name: 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide

The Article related to copper viologen thiocyanate complex preparation crystal structure, absorption spectra copper viologen thiocyanate complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Name: 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 31, 2014, Zhao, Chongjian; Li, Chuwen; Shen, Moyuan; Huang, Lanfen; Li, Qianhong; Hu, Mingyuan; Deng, Hong published an article.Electric Literature of 636-73-7 The title of the article was Syntheses, structures and photoluminescence of Cd(II) coordination polymers based on in situ synthesized bifunctional ligands. And the article contained the following:

By employing Cd(II) salt, NaN3, and CN-(CH2)n-NC (n = 1, 2) and with the absence or presence of secondary ligands, four new cadmium coordination frameworks, named, {[Cd4(btm)4(H2O)2]·3H2O}n (1); [Cd2(btm)2(H2O)]n (2); [Cd2(bte)(PMA)0.5(H2O)]n (3); and [Cd(tzp)(2,2′-bipy)]n (4) (H2btm = bis(tetrazole) methane: H2bte = 1,2-bis(tetrazole-5-yl)ethane; H2tzp = 1H-tetrazolate-5-propionic acid; bipy = bipyridine; PMA = 1,2,4,5-benzenetetracarboxylic acid) were synthesized via in situ hydrothermal reaction. Single crystal x-ray diffraction reveals that compounds 1-3 are all three-dimensional (3D) frameworks. Compound 1 is constructed by Cd1- and Cd3-btm2- layers and large bridging metalloligands. Compound 2 exhibits a 3D framework with two-dimensional (2D) Cd-btm2- (adopting μ6:κN1, N1′: κN2: κN3: κN4: κN3′: κN4’coordination mode) layers pillared by μ3:κN1, N1′: κN2: κN4′ btm2-. Compound 3 is built up by the Cd-bte2- layers and the linker PMA, with left- and right-handed helical chains arranged alternately. It is notable that btm2- takes on six different coordination modes in 1 and 2. Compound 4 represents a 2D layered framework, which can be simplified into a Shubnikov plane net (4.82̂) topol. network with 3-connected T shape linker tzp2- ligands. In addition, the research results show that compounds 1-4 exhibit different fluorescent behaviors and thermal stabilities. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Electric Literature of 636-73-7

The Article related to luminescence cadmium tetrazole coordination polymer, crystal structure cadmium tetrazole coordination polymer preparation, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Electric Literature of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 24, 2019, Yu, Henry; Clark, Michael; Bemis, Guy; Boyd, Michael; Chandupatla, Kishan; Collier, Philip; Deng, Hongbo; Dong, Huijun; Dorsch, Warren; Hoover, Russell R.; Johnson, Mac Arthur, Jr.; Kukarni, Shashank; Penney, Marina; Ronkin, Steven; Takemoto, Darin; Tang, Qing; Waal, Nathan D.; Wang, Tiansheng published a patent.Recommanded Product: 1227002-03-0 The title of the patent was Preparation of substituted oxazepanyl pyrimidinamines as antiproliferation compounds. And the patent contained the following:

The present invention provides compounds I [ring A = Ph, 5-7 membered saturated or partially unsaturated carbocyclic ring, 8-12 membered saturated or partially unsaturated bicyclic heterocyclic ring having 1-2 heteroatoms independently selected from N, O, or S, etc.; each R1 = (independently) H, or (halo)alkyl; or two R1 groups are optionally taken together with their intervening atoms to form 5-8 membered partially unsaturated fused carbocyclic ring; each of R2 = (independently) H, halo, CN, etc.; or two R2 groups are optionally taken together to form :O; or two R2 groups are optionally taken together with their intervening atoms to form 3-8 membered saturated spirocyclic ring having 0-2 heteroatoms independently selected from N, O or S; each R3 = (independently) H, OH, or alkyl; or two R3 groups are optionally taken together to form :O or :CH2; or two R3 groups are optionally taken together with their intervening atoms to form 3-8 membered saturated spirocyclic ring having 0-2 heteroatoms independently selected from N, O or S; or 5-8 membered saturated bridged bicyclic ring having 0-2 heteroatoms independently selected from N, O or S; X = O, S, CH2, etc.; m = 0-2; n = 0-5; p = 0-2] or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer). E.g., a multi-step synthesis of (R)-II and (S)-II, starting from 3-(tributylstannylmethoxy)propan-1-amine and 2-chloro-5-nitrobenzaldehyde, was described. Exemplified compounds I were evaluated in the Colo 205 reporter assay, HepG2 XBP1 reporter assay, and in the Calcium Flux assay (data given for representative compounds I). The experimental process involved the reaction of Methyl 2-amino-5-chloroisonicotinate(cas: 1227002-03-0).Recommanded Product: 1227002-03-0

The Article related to oxazepanyl pyrimidinamine preparation antiproliferative antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Other 7-Membered Rings and other aspects.Recommanded Product: 1227002-03-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kaczmarek, Lukasz published an article in 1985, the title of the article was Bipyridines. Part XVI. Synthesis of novel 1,2,3,7-oxatriazepine and 1,2,3-triazine fused systems by the diazotization of [2,2′-bipyridine]-3,3′-diamine.Computed Properties of 75449-26-2 And the article contains the following content:

In the diazotization reaction of [2,2′-bipyridine]-3,3′-diamine the corresponding tetrazonium salt I was formed. I was transformed, depending upon pH of the post-reaction solution, into 3a,4,5,8a,9,10-hexaaza-3a,8a-dihydropyrene 3a-oxide (II) or 6-oxa-4,5,6a,10,11,11a-hexaaza-6,6a,11a-trihydrocyclohepta[d,e,f]phenanthrene (III). III is isomerized to II in acidic media. Both isomers were transformed in acid into a mixture of (3-nitrosamino-2-pyridyl)-2-pyridin-3-ol and (3-amino-2-pyridyl)-2-pyridin-3-ol. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Computed Properties of 75449-26-2

The Article related to oxahexaazacycloheptaphenanthrene, hexazapyrene oxide, oxatriazepine fused, triazine fused, bipyridinediamine diazotization, Heterocyclic Compounds (More Than One Hetero Atom): Other 7-Membered Rings and other aspects.Computed Properties of 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On February 5, 2004, Kwan, Tricia Ann; Lagreca, Susan Deborah; Lippa, Blaise Scott; Morris, Joel; Wessel, Matthew David published a patent.Formula: C8H10BrN The title of the patent was Preparation of isothiazole derivatives as anticancer agents. And the patent contained the following:

The title compounds I [X = O or S; R1 = (substituted)heterocyclic aromatic ring; R2 = H, (cyclo)alkyl, alkenyl, alkynyl, etc.] were prepared Compounds I are useful as as anticancer agents (no data). Thus, reaction of 3-methanesulfonyl-5-(pyridin-4-ylamino)-isothiazole-4-carboxylic acid amide (preparation given) with (4-chlorophenyl)-methanethiol yielded compound II. The experimental process involved the reaction of 4-Bromo-2-isopropylpyridine(cas: 908267-63-0).Formula: C8H10BrN

The Article related to isothiazole derivative preparation anticancer, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Formula: C8H10BrN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On February 28, 1995, Liang, Zhaoxi; Wang, Xiaoyun; Yi, He published an article.Electric Literature of 52243-87-5 The title of the article was Electroreduction kinetics of alkyl polyviologens studied by in situ spectroscopy. And the article contained the following:

The electroreduction kinetics of several alkyl polyviologens (I), such as polypropyl viologen, polybutyl viologen, polyhexyl viologen as well as their resp. low mol. analogs (II) and a bisviologen were studied by in situ spectroscopy. The reaction order (α) and rate constant (κ) of the 1st electroreduction were calculated The effect of alkyl chain length (n) is obvious for II, κ values decrease in the order: PrV>BV>HxV. κ Values of I are lower than those of II and depend slightly on n. These facts may be attributed to the diffusion-controlled nature of the electroreduction process. The influences of viologen concentration, the supporting electrolyte and the pH value also were studied. In general, the memory time of I is longer than those of II. The experimental process involved the reaction of 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide(cas: 52243-87-5).Electric Literature of 52243-87-5

The Article related to electroreduction kinetics alkyl polyviologen spectroscopy, Electrochemistry: Electrodes, Electrode Reactions, and Electrode Potentials and other aspects.Electric Literature of 52243-87-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On March 1, 2019, Steinlechner, Christoph; Roesel, Arend F.; Oberem, Elisabeth; Paepcke, Ayla; Rockstroh, Nils; Gloaguen, Frederic; Lochbrunner, Stefan; Ludwig, Ralf; Spannenberg, Anke; Junge, Henrik; Francke, Robert; Beller, Matthias published an article.Application of 109660-12-0 The title of the article was Selective Earth-Abundant System for CO2 Reduction: Comparing Photo- and Electrocatalytic Processes. And the article contained the following:

The valorization of CO2 via photo- or electrocatalytic reduction constitutes a promising approach toward the sustainable production of fuels or value-added chems. using intermittent renewable energy sources. For this purpose, mol. catalysts are generally studied independently with respect to the photo- or the electrochem. application, although a unifying approach would be much more effective with respect to the mechanistic understanding and the catalyst optimization. In this context, we present a combined photo- and electrocatalytic study of three Mn diimine catalysts, which demonstrates the synergistic interplay between the two methods. The photochem. part of our study involves the development of a catalytic system containing a heteroleptic Cu photosensitizer and the sacrificial BIH reagent. The system shows exclusive selectivity for CO generation and renders turnover numbers which are among the highest reported thus far within the group of fully earth-abundant photocatalytic systems. The electrochem. part of our investigations complements the mechanistic understanding of the photochem. process and demonstrates that in the present case the sacrificial reagent, the photosensitizer, and the irradiation source can be replaced by the electrode and a weak Bronsted acid. The experimental process involved the reaction of 2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)pyridine(cas: 109660-12-0).Application of 109660-12-0

The Article related to carbon dioxide reduction photo electrocatalytic process earth, Electrochemistry: Electrodes, Electrode Reactions, and Electrode Potentials and other aspects.Application of 109660-12-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem