Month: November 2022

On July 12, 1996, Kelly, T. Ross; Lang, Fengrui published an article.Safety of Methyl 6-bromo-5-methoxypicolinate The title of the article was Total Synthesis of Dimethyl Sulfomycinamate. And the article contained the following:

Di-Me sulfomycinamate, a methanolysis product from the natural antibiotic sulfomycin I, is synthesized in 11 steps. The chem. of various pyridine, thiazole, and oxazole heterocycles and their coupling reactions under palladium catalysis are examined The key transformations in the synthesis are the selective palladium-catalyzed coupling reactions on a doubly-activated pyridine and the condensation reaction between bromo ketone and amide to form the oxazole moiety. The first preparation of oxazole triflates is described, as is some of their chem. properties. The experimental process involved the reaction of Methyl 6-bromo-5-methoxypicolinate(cas: 170235-18-4).Safety of Methyl 6-bromo-5-methoxypicolinate

The Article related to sulfomycinamate preparation, oxazole triflate preparation coupling reaction, pyridyl triflate preparation coupling thiazole, Biomolecules and Their Synthetic Analogs: Other Bacterial and Fungal Metabolites and other aspects.Safety of Methyl 6-bromo-5-methoxypicolinate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On September 30, 2021, Zhou, Enxing; Liu, Yuan; Wang, Hanping; Wang, Jing; Shao, Ning; Wu, Guanglong published a patent.Recommanded Product: 908267-63-0 The title of the patent was Preparation of heteroaryl compounds as casein kinase inhibitors. And the patent contained the following:

The title compounds with general formula I [wherein R1 = halogen; n = 0-2, X = independently C or N; R2 = absent or O; R3 = absent or CN; A = absent, a 4- to 7- membered (un)substituted cycloalkyl, heterocycloalkyl, a 5- to 6- membered (un)substituted heteroaryl, etc.; ring B = a 4- to 7-membered (un)substituted cycloalkyl, heterocycloalkyl, or a 5- to 6-membered (un)substituted heteroaryl, wherein up to 2 carbon atoms are replaced with a heteroatom selected from =N- or -O-] or pharmaceutically acceptable salts thereof were prepared novel casein kinase inhibitors. For example, compound II was prepared in a multi-step synthesis. Corresponding pharmaceutical compositions were also disclosed for the treatment of mood disorder, depression, bipolar disorder, solid tumor, blood cancer, lymphoma, breast cancer, melanoma, leukemia, liver cancer, and brain cancer. The experimental process involved the reaction of 4-Bromo-2-isopropylpyridine(cas: 908267-63-0).Recommanded Product: 908267-63-0

The Article related to preparation heteroaryl pyrazolopyrazine pyrimidine imidazopyrazine furopyridine, human casein kinase inhibitor treatment mood disorder cancer, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Recommanded Product: 908267-63-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On May 13, 2015, Liu, Jun; Dou, Chuandong published a patent.Electric Literature of 75449-26-2 The title of the patent was Bis(boron-nitrogen-bridged) bipyridyl and organic/high polymer material prepared with the same. And the patent contained the following:

The present invention relates to a kind of bis(boron-nitrogen-bridged) bipyridyl (I, R1 is 4-20 alkyl group, R2, e.g., Ph, F, Et etc.), and organic/high polymer material prepared with the same, belonging to organic/high polymer area of solar cell. The object of the invention is to take classic pyrene unit as starting point to develop new BN receptor unit for further expanding receptor material system. The bis(boron-nitrogen-bridged) bipyridyl in this invention contains BN unit so that it has a number of advantages: such as complanation structure is conducive to orderly close accumulation of material mol., so as to increase mobility of material carrier; BN coordination has strong electron-drawing action, which is conducive to reducing mol. energy level; introducing alkyl chain with different lengths contributes to regulating material dissoly.; reaction site with functionalization can be used for preparing organic/high polymer material, and it has good application prospect if applied to solar cell. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Electric Literature of 75449-26-2

The Article related to boron nitrogen bridged bipyridyl organic polymer material solar cell, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Electric Literature of 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 8, 2014, Yang, Yonggang; Li, Yi; Li, Baozong; Wang, Qingfeng published a patent.Application of 75449-26-2 The title of the patent was Chiral silsesquioxane containing arylene, manufacture method, and application in absorbent, chiral separation, and asymmetric catalysis. And the patent contained the following:

Title chiral silsesquioxane is homopolymer of I (OEt)3Si(CH2)mNHC(O)NHCH(R)C(O)NH-A-NHC(O)CH(R)NHC(O)NH(CH2)mSi(OEt)3; wherein R is residual group of valine, isoleucine, alanine, or phenylalanine, A is aromatic group of diamine, and m is integer of 3-10. Title manufacture method comprises the steps: (1) reacting Boc-protected amino acid with aromatic diamine to give Boc-protected intermediate; (2) deprotecting Boc group; (3) reacting deprotected intermediate with isocyanate (EtO)3Si(CH2)mNCO (m is integer of 3-10) to give monomer; and (4) polycondensing the monomer to obtain chiral silsesquioxane. Title chiral silsesquioxane has stable chem. property, simple production, and convenient use, has good adsorption effect on aryl compound and heavy metal ion, also has great application value in chiral resolution and asym. catalysis. In an example, I (R = iPr, A = biphenylene, m = 3) was manufactured from Boc-L-valine, 4,4′-diaminobiphenyl, and (3-isocyanato)propyltriethoxysilane; I was polymerized to give right-hand helical fiber with diameter 50-100 nm and length 2-10 μm. The obtained silsesquioxane 50 mg was added to nitrobenzene/cyclohexane solution (volume ratio 1:99) 850 μl; after 5 h, nitrobenzene 19.3 % was absorbed by silsesquioxane, which indicated that the silsesquioxane could be used as absorbent to absorb aromatic compound The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Application of 75449-26-2

The Article related to chiral silsesquioxane arylene manufacture absorbent resolution asym catalysis, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Application of 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On July 15, 2013, Duan, Lele; Wang, Lei; Inge, A. Ken; Fischer, Andreas; Zou, Xiaodong; Sun, Licheng published an article.Category: pyridine-derivatives The title of the article was Insights into Ru-Based Molecular Water Oxidation Catalysts: Electronic and Noncovalent-Interaction Effects on Their Catalytic Activities. And the article contained the following:

A series of Ru-bda water oxidation catalysts [Ru(bda)L2] (H2bda = 2,2′-bipyridine-6,6′-dicarboxylic acid; L = [HNEt3][3-SO3-pyridine], 1; 4-(EtOOC)-pyridine, 2; 4-bromopyridine, 3; pyridine, 4; 4-methoxypyridine, 5; 4-(Me2N)-pyridine, 6; 4-[Ph(CH2)3]-pyridine, 7) were synthesized with electron-donating/-withdrawing groups and hydrophilic/hydrophobic groups in the axial ligands. These complexes were characterized by 1H NMR spectroscopy, high-resolution mass spectrometry, elemental anal., and electrochem. In addition, complexes 1 and 6 were further identified by single crystal X-ray crystallog., revealing a highly distorted octahedral configuration of the Ru coordination sphere. All of these complexes are highly active toward CeIV-driven (CeIV = Ce(NH4)2(NO3)6) water oxidation with oxygen evolution rates up to 119 mols of O2 per mol of catalyst per s. Their structure-activity relationship was investigated. Electron-withdrawing and noncovalent interactions (attraction) exhibit pos. effect on the catalytic activity of Ru-bda catalysts. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Category: pyridine-derivatives

The Article related to ruthenium based mol water oxidation catalyst electronic noncovalent interaction, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Reaction Kinetics and other aspects.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On January 8, 2014, Neudeck, Sven; Maji, Somnath; Lopez, Isidoro; Meyer, Steffen; Meyer, Franc; Llobet, Antoni published an article.Electric Literature of 636-73-7 The title of the article was New Powerful and Oxidatively Rugged Dinuclear Ru Water Oxidation Catalyst: Control of Mechanistic Pathways by Tailored Ligand Design. And the article contained the following:

A new powerful and oxidatively rugged pyrazolate-based water oxidation catalyst of formula {[RuII(py-SO3)2(H2O)]2(μ-Mebbp)}-, 1(H2O)2-, has been prepared and thoroughly characterized spectroscopically and electrochem. This new catalyst has been conceived based on a specific ligand tailoring design, so that its performance has been systematically improved. It was also demonstrated how subtle ligand modifications cause a change in the O-O bond formation mechanism, thus revealing the close activation energy barriers associated with each pathway. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Electric Literature of 636-73-7

The Article related to powerful oxidatively rugged dinuclear ruthenium water oxidation catalyst, control mechanistic pathway tailored ligand design, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Reaction Kinetics and other aspects.Electric Literature of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Shirra, Alexander; Suckling, Colin J. published an article in 1977, the title of the article was Pyridinium salts and dihydropyridines; mechanistic studies of the redox reaction between pyridinium salts and alkoxides in tetrahydrofuran.SDS of cas: 636-73-7 And the article contains the following content:

A model system for NAD-dependent redox reactions was designed to assess the involvement of covalent adducts as intermediates. The system consisted of 3-substituted 1-n-heptylpyridinium salts and substituted benzyl alkoxides. Although covalent adducts were found in the reaction mixture, studies of substituent effects and other structural variations did not show that A covalent intermediate is on the reaction path. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).SDS of cas: 636-73-7

The Article related to redox pyridinium alkoxide mechanism, nad redox model system, Physical Organic Chemistry: Oxidation-Reduction Reactions (Including Hydrogenation) and other aspects.SDS of cas: 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On May 17, 2018, Tsai, Jui-Yi; Xia, Chuanjun; Lin, Chun; Palacios, Adrian U.; Onate, Enrique; Esteruelas, Miguel A.; Boudreault, Pierre-Luc T.; Bajo, Sonia; Olivan, Montserrat published a patent.HPLC of Formula: 1349171-28-3 The title of the patent was Organic electroluminescent iridium complexes having three bidentate ligands. And the patent contained the following:

Methods of method of preparing a metal complex having the formula M(LA)(LB)(LC) are discussed which entail providing a precursor metal complex having the formula (LA)(LB)M-(X)2-M(LA)(LB), in which M is a metal, ligand LA and ligand LB (X = halogen; rings A-D are each independently selected from a 5-6 membered carbocyclic or heterocyclic ring; RA-RD each independently represent mono substitution up to the maximum possible number of substitutions, or no substitution; Z1-Z2 are each independently C or N; RA-RD, RX-RZ are independently selected from H, D, halide, alkyl, etc.; and where any adjacent substituents are optionally joined or fused into a ring); reacting the precursor metal complex with a first reagent to obtain the metal complex having the formula M(LA)(LB)(LC), where LC (RX-RZ are each independently selected from H, D, halide, alkyl, etc.), rings C’ and D’ are each independently selected from a 5-6 membered carbocyclic or heterocyclic ring; C1′ = anionic donor C atom; C2′ = neutral carbene C atom; RC’-RD’ are independently selected from H, D, halide, alkyl, etc., and rings A’ and B’ are each independently selected from a 5-6 membered carbocyclic or heterocyclic ring; Z1′ = anionic donor C atom; Z2′ = neutral N atom; RA’-RB’ are independently selected from H, D, halide, alkyl, etc. The experimental process involved the reaction of 2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridine(cas: 1349171-28-3).HPLC of Formula: 1349171-28-3

The Article related to organic electroluminescent iridium complex bidentate ligand, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.HPLC of Formula: 1349171-28-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 15, 2014, Cha, Sun Uk; Jung, Gyeong Seok; Park, Seok Bae; Kim, Hui Dae; Lee, Yu Rim; Song, Ju Man; Hwang, Mun Chan published a patent.Formula: C9H14N2 The title of the patent was Asymmetric pyrene derivative comprising heteroaryl amine as electroluminescent dopant for organic light-emitting device. And the patent contained the following:

The present invention relates to an asym. pyrene derivative comprising heteroaryl amine, and an organic light-emitting device comprising the same. The asym. pyrene derivative comprising heteroaryl amine is represented by formula I or II (Py = substituted or unsubstituted pyridinyl; Het1-Het3 = heterogeneous atom selected from oxygen, nitrogen, sulfur and silicon, C2-C50 heteroaryl group; Z = hydrogen, deuterium, C1-C30 alkyl group, C5-C50 aryl group, C2-C30 alkenyl group, C2-C20 alkynyl group, C3-C30 cycloalkyl group, C5-C30 cycloalkenyl group, etc.; m = integer of 1-8 for formula I and 1-9 for formula II, where the substitution is selected from deuterium, cyano group, halogen, hydroxyl group, nitro group, C1-C24 alkyl group, etc.). The organic light-emitting device comprises: a first electrode; a second electrode placed opposite to the first electrode; and an organic layer placed between the first and second electrodes, where the organic layer includes an organic light-emitting compound i.e. asym. pyrene derivative The organic layer is selected from hole injection layer having hole injection function, hole transport layer having hole transport function, functional layer, light-emitting layer, electron transport layer, and electron injection layer. According to the present invention, the asym. pyrene derivative has excellent luminous efficiency and high-color purity, and is utilized in the organic light-emitting device such as flat panel display device, flexible display device, monochromatic or white flexible lighting device, etc. The experimental process involved the reaction of 6-(tert-Butyl)pyridin-3-amine(cas: 39919-70-5).Formula: C9H14N2

The Article related to asym pyrene heteroaryl amine electroluminescent dopant flat panel display, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.Formula: C9H14N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 15, 2014, Cha, Sun Uk; Jung, Gyeong Seok; Park, Seok Bae; Kim, Hui Dae; Lee, Yu Rim; Song, Ju Man; Hwang, Mun Chan published a patent.Safety of 6-(tert-Butyl)pyridin-3-amine The title of the patent was Amine group substituted asymmetric pyrene derivative comprising pyridinyl group as electroluminescent dopant and/or organic semiconductor materials for organic light-emitting device. And the patent contained the following:

The present invention relates to an amine group substituted asym. pyrene derivative, and an organic light-emitting device comprising the same. The amine group substituted asym. pyrene derivative comprising pyridinyl group is represented by formula I (Py1, Py2 = substituted or unsubstituted pyridinyl group; Ar1, Ar2 = substituted or unsubstituted C1-C30 alkyl group, substituted or unsubstituted C3-C30 cycloalkyl group, substituted or unsubstituted C5-C50 aryl group, C2-C50 heteroaryl group having one or more substituted or unsubstituted atoms selected from oxygen, nitrogen, sulfur and silicon; Z = hydrogen, deuterium, substituted or unsubstituted C1-C30 alkyl group, substituted or unsubstituted C5-C50 aryl group, substituted or unsubstituted C2-C30 alkenyl group, substituted or unsubstituted C2-C20 alkynyl group, substituted or unsubstituted C3-C30 cycloalkyl group, substituted or unsubstituted C5-C30 cycloalkenyl group, etc.; and m = integer of 1-8, where the substituted or unsubstituted substitution is selected from deuterium, cyano group, halogen, hydroxyl group, nitro group, C1-C24 alkyl group, etc.). The organic light-emitting device comprises: a first electrode; a second electrode placed opposite to the first electrode; and an organic layer placed between the first and second electrodes, where the organic layer includes an organic light-emitting compound i.e. amine group substituted asym. pyrene derivative The organic layer is selected from hole injection layer having hole injection function, hole transport layer having hole transport function, functional layer, light-emitting layer, electron transport layer, and electron injection layer. According to the present invention, the amine group substituted asym. pyrene derivative has excellent luminous efficiency and high-color purity, and is utilized in the organic light-emitting device for producing full-color display. The experimental process involved the reaction of 6-(tert-Butyl)pyridin-3-amine(cas: 39919-70-5).Safety of 6-(tert-Butyl)pyridin-3-amine

The Article related to amine group asym pyrene derivative pyridinyl electroluminescent dopant oled, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.Safety of 6-(tert-Butyl)pyridin-3-amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem