Month: November 2022

Electric Literature of C12H12N2In 2022 ,《A self-oscillating gel system with complex dynamic behavior based on a time delay between the oscillations》 was published in Soft Matter. The article was written by Li, Xiuchen; Li, Jie; Zheng, Zhaohui; Deng, Jinni; Pan, Yi; Ding, Xiaobin. The article contains the following contents:

The time delay existing between the chem. oscillation and mech. oscillation (C-M delay) in a self-oscillating gel (SOG) system is observable in previous exptl. studies. However, how the C-M delay affects the dynamic behavior of a large anisotropic SOG has not been quantified or reported systematically. In this study, we observed that the oscillation period increases with a decrease in the crosslinking d. of the anisotropic SOG, and this determined whether regular mech. oscillation occurs. Unlike before, the disrupted mech. oscillations interestingly tend to be regular and periodic under visible light, which is an inhibitor for the B-Z reaction incorporating the Ru complex as a catalyst (Ru-BZ reaction). Moreover, the study of the C-M delay at different scales has far-reaching implications for intelligent soft actuators. The experimental part of the paper was very detailed, including the reaction process of 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Electric Literature of C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.Electric Literature of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Intramolecular electrochemical dehydrogenative N-N bond formation for the synthesis of 1,2,4-triazolo[1,5-a]pyridines》 was written by Li, Yong; Ye, Zenghui; Chen, Na; Chen, Zhenkun; Zhang, Fengzhi. Formula: C6H4N2This research focused ontriazolopyridine preparation green chem; amidine pyridyl electrochem dehydrogenation. The article conveys some information:

A metal- and oxidant-free intramol. dehydrogenative N-N bond formation has been developed under mild and scalable electrolytic conditions. Various valuable 1,2,4-triazolo[1,5-a]pyridines I (R1 = t-Bu, cyclopropyl, 2,6-dichlorophenyl, 2-naphthyl, pyridin-4-yl, etc.; R2 = H, Me; R3 = H, Me, Et, F, Cl, 4-methylphenyl, 2-thiophenyl; R4 = H, Me, MeO; R5 = H, Me, Cl; R3R4 = CH=CH-CH=CH) were synthesized efficiently from the readily available N-(2-pyridyl)amidines II. The reactions were conducted in a simple undivided cell under constant current conditions with n-Bu4NBr as both the redox mediator and the electrolyte. This protocol was applied to the efficient synthesis of key intermediates for anti-diabetic compounds After reading the article, we found that the author used 4-Cyanopyridine(cas: 100-48-1Formula: C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Formula: C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Manganese-Catalyzed Synthesis of Imines from Primary Alcohols and (Hetero)Aromatic Amines》 was written by Raydan, Daniel; Friaes, Sofia; Viduedo, Nuno; Santos, A. Sofia; Gomes, Clara S. B.; Royo, Beatriz; Marques, M. Manuel B.. Computed Properties of C5H5BrN2 And the article was included in Synlett on August 31 ,2022. The article conveys some information:

Herein, the synthesis of a wide variety of imines through oxidative coupling of alcs. and aromatic amines catalyzed by Mn complexes bearing NN triazole ligands was described. A wide variety of imines in excellent yields (up to 99%) was prepared Mn-based catalysts proved to be highly efficient and versatile, allowing for the first time the preparation of several imines containing N-based heterocycles. In addition to this study using 2-Bromopyridin-3-amine, there are many other studies that have used 2-Bromopyridin-3-amine(cas: 39856-58-1Computed Properties of C5H5BrN2) was used in this study.

2-Bromopyridin-3-amine(cas: 39856-58-1) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Computed Properties of C5H5BrN2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Substituent Effects of 2-Pyridones on Selective O-Arylation with Diaryliodonium Salts: Synthesis of 2-Aryloxypyridines under Transition-Metal-Free Conditions》 was written by Li, Xiao-Hua; Ye, Ai-Hui; Liang, Cui; Mo, Dong-Liang. Application In Synthesis of Methyl 6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylate And the article was included in Synthesis on April 30 ,2018. The article conveys some information:

An efficient transition-metal-free strategy to synthesize 2-aryloxypyridine derivatives was developed by a selective O-arylation of 2-pyridones with diaryliodonium salts. The reaction was compatible with a series of functional groups for 2-pyridones and diaryliodonium salts such as halides, nitro, cyano and ester groups. The substituents at the C6-position of 2-pyridones favored O-arylation products because of steric hindrance. The reaction was easily performed on a gram-scale and 6-chloro-2-pyridone was a good precursor to access various unsubstituted 2-aryloxypyridines by dehalogenation. A P2Y1 lead compound analog I could be prepared in good yield over two steps. The experimental part of the paper was very detailed, including the reaction process of Methyl 6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylate(cas: 77837-09-3Application In Synthesis of Methyl 6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylate)

Methyl 6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylate(cas: 77837-09-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. Application In Synthesis of Methyl 6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylateThe lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Viologen Derivatives Extended with Aromatic Rings Acting as Negative Electrode Materials for Use in Rechargeable Molecular Ion Batteries》 was written by Kato, Minami; Sano, Hikaru; Kiyobayashi, Tetsu; Yao, Masaru. Application of 624-28-2This research focused onviologen derivative aromatic ring electrode rechargeable mol battery; anions; charge transfer; energy storage; fluorescence; redox chemistry. The article conveys some information:

Many types of batteries have been proposed as next-generation energy-storage systems. One candidate is a rocking-chair-type “”mol. ion battery”” in which a mol. ion, instead of Li+, works as a charge carrier. Previously, a viologen-type derivative is reported as a neg. electrode material that releases and receives PF6- anions during the charge-discharge process; however, its redox potential was not satisfactorily low. Further, the two potential plateaus of this material (difference = 0.5 V) should be reduced. In this study, PF6- salts of viologen (bipyridinium) derivatives extended by aromatic rings were synthesized to obtain a neg. electrode material with a lower redox potential and small potential change during the charge and discharge processes. Some of the synthesized viologen derivatives were fluorescent even in solid-state electrodes. In the half-cell configuration, the prepared neg. electrode materials showed average voltages of approx. 2 V (vs. Li+/Li), which is lower than that of conventional viologen derivatives The experimental process involved the reaction of 2,5-Dibromopyridine(cas: 624-28-2Application of 624-28-2)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Application of 624-28-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2017,Zhou, Pei; Wang, Lei; Wu, Guangyu; Zhou, Yuting; Hegazy, Mohammad; Huang, Xin published 《In Situ Generation of Core-Shell Protein-Based Microcapsules with Regulated Ion Absorbance Capacity》.ChemistrySelect published the findings.COA of Formula: C7H9NO The information in the text is summarized as follows:

In this study, we presented a way to generate organic/protein hybrid core-shell micro-compartment structure by in situ generating poly(o-phenylenediamine) (POPD) nanoparticles inside a robust and flexible protein-based shell. Both the size and number of the generated POPD core inside the protein microcapsules could be well varied by using different oxidants including, H2O2, tert-Bu hydroperoxide (TBHP) and glucose oxidase (GO)/ glucose (Glu). Significantly, via operating the membrane permeability by either the cleavage of the conjugated polymer or addnl. formation of tannic acid/Fe3+ complex outer shell, the adsorption capacity towards Cu2+ of the constructed multiple cores in single shell model could be well modulated. In general, our studies contribute to the establishment of an improved model with its potential applications in catalysis system, biotechnol. and biomedicine. In the part of experimental materials, we found many familiar compounds, such as 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2COA of Formula: C7H9NO)

2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. COA of Formula: C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Tetrahedron included an article by Wan, Xiao-Min; Liu, Zi-Lin; Liu, Wan-Qing; Cao, Xiao-Niu; Zhu, Xinju; Zhao, Xue-Mei; Song, Bing; Hao, Xin-Qi; Liu, Guoji. Computed Properties of C6H4N2. The article was titled 《NNN pincer Ru(II)-catalyzed dehydrogenative coupling of 2-aminoarylmethanols with nitriles for the construction of quinazolines》. The information in the text is summarized as follows:

An efficient NNN pincer Ru(II)-catalyzed preparation of quinazolines via acceptorless dehydrogenative strategy was developed. Under the optimized conditions, a broad range of substituted o-aminobenzyl alcs. and (hetero)aryl or alkyl nitriles were well tolerated to afford various 2-substituted quinazolines in high yields. Subsequently, a set of control experiments was performed to elucidate the reaction mechanism, which underwent alc. oxidation, nitrile hydration and cyclocondensation steps. This protocol was featured with several advantages, such as environmental benignity, operational simplicity, broad substrate scope (compatible with aliphatic nitriles, up to 87% yield) and short reaction time (mostly in 2 h). The results came from multiple reactions, including the reaction of 4-Cyanopyridine(cas: 100-48-1Computed Properties of C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Computed Properties of C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Chemical Science included an article by Cao, Jia; Wang, Guoqiang; Gao, Liuzhou; Chen, Hui; Liu, Xueting; Cheng, Xu; Li, Shuhua. Application In Synthesis of 4-Cyanopyridine. The article was titled 《Perfluoroalkylative pyridylation of alkenes via 4-cyanopyridine-boryl radicals》. The information in the text is summarized as follows:

A metal-free and photo-free method for the perfluoroalkylative pyridylation of alkenes R1R2C=CH2 [R1 = 4-MeC6H4, 2H-1,3-benzodioxol-5-yl, naphthalen-2-yl, etc.; R2 = H, Me, Et, Pr; R1R2 = -(CH2)5-] has been developed via a combination of computational and exptl. studies. D. functional theory calculations and control experiments indicate that the homolysis of R3X [R3 = CF3, CF2CF2Cl, CF(CF3)2, etc.; X = Br, I] bonds by the 4-cyanopyridine-boryl radicals in situ generated from 4-cyanopyridine and B2pin2 is the key step. Sequential addition of R3 radicals to alkenes and the selective cross-coupling of the resulting alkyl radicals and 4-cyanopyridine-boryl radicals gives alkene difunctionalization products I with a quaternary carbon center. This method exhibits a broad substrate scope and good functional group compatibility. In the part of experimental materials, we found many familiar compounds, such as 4-Cyanopyridine(cas: 100-48-1Application In Synthesis of 4-Cyanopyridine)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Application In Synthesis of 4-Cyanopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Metal-Free Radical-Mediated C(sp3)-H Heteroarylation of Alkanes》 was published in Organic Letters in 2020. These research results belong to Shao, Xin; Wu, Xinxin; Wu, Shuo; Zhu, Chen. COA of Formula: C6H4N2 The article mentions the following:

Herein we disclose a metal-free, N/O-centered radical-promoted Minisci reaction, in which the coupling of various heteroarenes with simple alkanes proceeds under mild conditions. The reaction conditions are neutral; no extra acid is added to preactivate N-heteroarenes in the Minisci reaction. The N-/O-centered radicals are generated directly from amide (TsNHMe) or alc. (CF3CH2OH) under visible-light irradiation This green and eco-friendly synthetic process may find potential use in medicinal chem. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1COA of Formula: C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.COA of Formula: C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Highly efficient removal of Cu(II) by novel dendritic polyamine-pyridine-grafted chitosan beads from complicated salty and acidic wastewaters》 was published in RSC Advances in 2020. These research results belong to Wang, Li-Li; Ling, Chen; Li, Bang-Sen; Zhang, Da-Shuai; Li, Chen; Zhang, Xiao-Peng; Shi, Zai-Feng. Reference of Bis(pyridin-2-ylmethyl)amine The article mentions the following:

In this study, dendritic polyamine chitosan beads with and without 2-aminomethyl pyridine were facilely prepared and characterized. Compared to CN (without the pyridine function), more adsorption active sites, larger pores, higher nitrogen content, higher sp. surface area, and higher strength could be obtained for CNP (with the pyridine function). CNP microspheres afforded a larger adsorption capacity than those obtained by CN for different pH values; further, the uptake amounts of Cu(II) were 0.84 and 1.12 mmol g-1 for CN and CNP beads, resp., at pH 5. The CNP microspheres could scavenge Cu(II) from highly acidic and salty solutions: the maximum simulated uptake amount of 1.93 mmol g-1 at pH 5 could be achieved. Due to the strong bonding ability and weakly basic property of pyridine groups, the adsorption capacity of Cu(II) at pH 1 was 0.75 mmol g-1 in highly salty solutions, which was comparative to those obtained from the com. pyridine chelating resin M4195 (QCu(II) = 0.78 mmol g-1 at pH 1). In addition, a distinct salt-promotion effect could be observed for CNP beads at both pH 5 and 1. Therefore, the prepared adsorbent CNP beads can have promising potential applications in the selective capturing of heavy metals in complex solutions with higher concentrations of H+ and inorganic salts, such as wastewaters from electroplating liquid and battery industries. In the experiment, the researchers used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Reference of Bis(pyridin-2-ylmethyl)amine)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. As a tridentate ligand this compound provides three nitrogen donors that affords good selectivity for Zn2+ over biologically relevant metals such as Na+, K+, Mg2+ and Ca2+, and leaves coordination sites free for anion binding. Reference of Bis(pyridin-2-ylmethyl)amine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem