Month: November 2022

《CO2 Hydrogenation to Formate Catalyzed by Ru Coordinated with a N,P-Containing Polymer》 was published in ACS Catalysis in 2020. These research results belong to Chen, Bingfeng; Dong, Minghua; Liu, Shulin; Xie, Zhenbing; Yang, Junjuan; Li, Shaopeng; Wang, Yanyan; Du, Juan; Liu, Huizhen; Han, Buxing. Name: 2,6-Diaminopyridine The article mentions the following:

Development of high-performance catalysts for carbon dioxide (CO2) hydrogenation is crucial for CO2 utilization. Herein, a heterogeneous catalyst for CO2 hydrogenation to formate was developed by coordinating the mononuclear Ru3+ center (Ru hereafter) with a N,P-containing polymer, which was synthesized from phosphonitrilic chloride trimer and 2,6-diaminopyridine. Multiple nitrogen functionalities in the polymer (N content: 25.9 wt %) containing pyridine nitrogen and phosphazene nitrogen not only provided an electron-rich coordination environment for stabilizing mononuclear Ru center but also facilitated CO2 conversion by interacting with CO2 mols. The polymer-coordinated mononuclear Ru catalysts (Ru/p-dop-POMs) could promote the hydrogenation of CO2 to formate with a turnover number (TON) up to 25.4 x 103 in aqueous solutions, and the concentration of formate in the solution could reach 3.4 mol/L. DFT calculations revealed that the electron-rich mononuclear Ru site could promote H2 dissociation, which is the rate-determining step in the reaction, thereby enhancing the catalytic activity. Systemic studies demonstrated that the synergistic effect between individually electron-rich Ru centers and nitrogen-rich polymer enhanced catalytic efficiency. In the experimental materials used by the author, we found 2,6-Diaminopyridine(cas: 141-86-6Name: 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Name: 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Fabrication and Application of Graphene Supported Diimine-Palladium Complex Catalyst for Organic Synthesis》 was published in ChemistrySelect in 2020. These research results belong to Sun, Yunlong; Li, Tian. Name: 2,6-Dibromopyridine The article mentions the following:

In this paper, a diimine palladium complex with suitable steric hindrance of iso-Pr groups and electron supply provided excellent protection for palladium active centers was synthesized and anchored on graphene oxide (GO) to obtain a reusable heterogeneous catalyst (Pd-DI@GO). The XPS results confirmed the effective loading of palladium and the interaction between palladium and ligand. The ICP-AES data verified the Pd content of catalyst was 5.04 wt% and confirmed extremely small amount Pd leaching in Suzuki reaction (<1 ppm). The Pd-DI@GO could catalyze Suzuki reaction and C-H direct arylation reaction of aryl bromides and arylboronic acids/heterocycles to afford biaryls R-R1 [R = Ph, 4-MeC6H4, 2-MeOC6H4, etc.; R1 = Ph, 1-naphthyl, 2-pyridyl, etc] and R2-R3 [R2 = Ph, 4-ClC6H4, 4-tBuC6H4, etc. R3 = 2,4-(Me)2-5-thiazolyl, 2-Me-5-thiazolyl, 4-Me-5-thiazolyl] with high yields. Notably, the Pd-DI@GO could be recycled after Suzuki reaction via filtration or centrifugation easily, presented a yield above 90% for the 4th run. After reading the article, we found that the author used 2,6-Dibromopyridine(cas: 626-05-1Name: 2,6-Dibromopyridine)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Name: 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Understanding the Role of Surface Heterogeneities in Electrosynthesis Reactions》 was written by Carvalho, O. Quinn; Adiga, Prajwal; Murthy, Sri Krishna; Fulton, John L.; Gutierrez, Oliver Y.; Stoerzinger, Kelsey A.. Formula: C7H7NO And the article was included in iScience in 2020. The article conveys some information:

In this perspective, we highlight the role of surface heterogeneity in electrosynthesis reactions. Heterogeneities may come in the form of distinct crystallog. facets, boundaries between facets or grains, or point defects. We approach this topic from a foundation of surface science, where signatures from model systems provide understanding of observations on more complex and higher-surface-area materials. In parallel, probe-based techniques can inform directly on spatial variation across electrode surfaces. We call attention to the role spectroscopy can play in understanding the impact of these heterogeneities in electrocatalyst activity and selectivity, particularly where these surface features have effects extending into the electrolyte double layer. The experimental process involved the reaction of 4-Acetylpyridine(cas: 1122-54-9Formula: C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Formula: C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Electroreductive 4-Pyridylation of Electron-deficient Alkenes with Assistance of Ni(acac)2》 was written by Zhang, Sheng; Li, Lijun; Li, Xinru; Zhang, Junqi; Xu, Kun; Li, Guigen; Findlater, Michael. Electric Literature of C6H4N2 And the article was included in Organic Letters in 2020. The article conveys some information:

An electroreductive 4-pyridylation of activated alkenes was developed in an undivided cell with the assistance of Ni(acac)2 (acac = acetylacetone). This novel protocol was compatible with a broad range of electron-poor alkenes, which were commonly regarded as challenging substrates in the previous conventional approaches. Moreover, a series of cyclic voltammetric experiments were conducted to reveal the unique role of Ni(acac)2 differentiating reduction process of reaction partners. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanopyridine(cas: 100-48-1Electric Literature of C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Electric Literature of C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Synergistic Enhancement Effects of Carbon Quantum Dots and Au Nanoclusters for Cathodic ECL and Non-enzyme Detections of Glucose》 was written by Han, Shuang; Gao, Yuan; Li, Lin; Lu, Beibei; Zou, Yongxing; Zhang, Ling; Zhang, Jiaheng. Quality Control of Pyridin-3-ylboronic acid And the article was included in Electroanalysis in 2020. The article conveys some information:

In this study, we found that glucose enhance electrochemiluminescence (ECL) intensity of both Au nanoclusters (Au NCs) and carbon quantum dots (CQDs) with K2S2O8 as the co-reactants. The enhancing effects by Au NCs and CQDs were overlapped, enabling the detection of glucose. The increased ECL intensity of glucose was linear with the logarithm of concentrations of glucose in the range of 50μM-3.0 mM, and the limit of detection is 20μM. Anti-interruption ability was achieved, and ascorbic acid, urea, and uric acid had little influence to glucose detection. This method realized the direct detection of glucose by enhancing ECL of Au NCs and CQDs, which was fast and economic, possessing potential applications for glucose detection in human serum. After reading the article, we found that the author used Pyridin-3-ylboronic acid(cas: 1692-25-7Quality Control of Pyridin-3-ylboronic acid)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Quality Control of Pyridin-3-ylboronic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Iridium-Catalyzed ortho-C-H Borylation of Thioanisole Derivatives Using Bipyridine-Type Ligand》 was written by Zeng, Jialin; Naito, Morio; Torigoe, Takeru; Yamanaka, Masahiro; Kuninobu, Yoichiro. Safety of 2,5-Dibromopyridine And the article was included in Organic Letters in 2020. The article conveys some information:

A simple iridium catalytic system was developed that allows for a variety of 2-borylthioanisoles, e.g. I, to be easily synthesized via ortho-selective C-H borylation of thioanisole derivatives Once introduced, boryl and methylthio groups were converted by palladium-catalyzed transformations. D. functional theory calculations revealed that weak interactions, such as hydrogen bonding between the C-H bond of the SCH3 group and the oxygen atom of the boryl ligand, control the ortho-selectivity. The results came from multiple reactions, including the reaction of 2,5-Dibromopyridine(cas: 624-28-2Safety of 2,5-Dibromopyridine)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Safety of 2,5-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Luo, Mu-Jia; Ouyang, Xuan-Hui; Zhu, Yan-Ping; Li, Yang; Li, Jin-Heng published their research in Green Chemistry in 2021. The article was titled 《Metal-free electrochemical [3 + 2] heteroannulation of anilines with pyridines enabled by dual C-H radical aminations》.Related Products of 1122-54-9 The article contains the following contents:

An unprecedented metal-/external-oxidant-free electrochem. intermol. [3+2] heteroannulation of anilines with electron-deficient pyridines enabled by dual C-H radical aminations for producing functionally diverse benzo[4,5]imidazo[1,2-a]pyridines was described. The site-selectivity of aminations of aryl C(sp2)-H bonds relied on the electronic effect of two reaction partners: each contributed two reactive sites (a C(sp2)-H bond and a nitrogen atom-based functional group) and the electron-withdrawing groups at the 4 position of the pyridine ring were crucial. Mechanistic studies have shown that this method sequence consisted of the generation of the nitrogen-centered radical (NCR) and the pyridine radical anion, radical coupling, and dual C-N aminations. In the experiment, the researchers used 4-Acetylpyridine(cas: 1122-54-9Related Products of 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Related Products of 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kunfi, Attila; Jablonkai, Istvan; Gazdag, Tamas; Mayer, Peter J.; Kalapos, Peter Pal; Nemeth, Krisztina; Holczbauer, Tamas; London, Gabor published their research in RSC Advances in 2021. The article was titled 《A photoresponsive palladium complex of an azopyridyl-triazole ligand: light-controlled solubility drives catalytic activity in the Suzuki coupling reaction》.Product Details of 13534-97-9 The article contains the following contents:

Herein, the design and synthesis of a click-derived Pd-complex merged with a photoswitchable azobenzene unit is presented. While in the trans-form of the switch the complex showed limited solubility, the photogenerated cis-form rendered the mol. soluble in polar solvents. This light-controllable solubility was exploited to affect the catalytic activity in the Suzuki coupling reaction. The effect of the substrate and catalyst concentration and light intensity on the proceeding and outcome of the reaction was studied. Dehalogenation of the aryl iodide starting material was found to be a major side reaction; however, its occurrence was dependent on the applied light intensity. The experimental process involved the reaction of 6-Bromopyridin-3-amine(cas: 13534-97-9Product Details of 13534-97-9)

6-Bromopyridin-3-amine(cas: 13534-97-9) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.Product Details of 13534-97-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yu, Yi; Mallick, Suman; Wang, Mao; Boerjesson, Karl published their research in Nature Communications in 2021. The article was titled 《Barrier-free reverse-intersystem crossing in organic molecules by strong light-matter coupling》.HPLC of Formula: 624-28-2 The article contains the following contents:

Strong light-matter coupling provides the means to challenge the traditional rules of chem. In particular, an energy inversion of singlet and triplet excited states would be fundamentally remarkable since it would violate the classical Hund’s rule. An organic chromophore possessing a lower singlet excited state can effectively harvest the dark triplet states, thus enabling 100% internal quantum efficiency in elec. pumped light-emitting diodes and lasers. Here we demonstrate unambiguously an inversion of singlet and triplet excited states of a prototype mol. by strong coupling to an optical cavity. The inversion not only implies that the polaritonic state lies at a lower energy, but also a direct energy pathway between the triplet and polaritonic states is opened. The intrinsic photophysics of reversed-intersystem crossing are thereby completely overturned from an endothermic process to an exothermic one. By doing so, we show that it is possible to break the limit of Hund’s rule and manipulate the energy flow in mol. systems by strong light-matter coupling. Our results will directly promote the development of organic light-emitting diodes based on reversed-intersystem crossing. Moreover, we anticipate that it provides the pathway to the creation of elec. pumped polaritonic lasers in organic systems. The experimental process involved the reaction of 2,5-Dibromopyridine(cas: 624-28-2HPLC of Formula: 624-28-2)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.HPLC of Formula: 624-28-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sun, Deli; Ma, Guobin; Zhao, Xinluo; Lei, Chuanhu; Gong, Hegui published their research in Chemical Science in 2021. The article was titled 《Nickel-catalyzed asymmetric reductive arylation of α-chlorosulfones with aryl halides》.Formula: C5H3BrClN The article contains the following contents:

An asym. Ni-catalyzed reductive cross-coupling of aryl/heteroaryl halides with racemic α-chlorosulfones to afford enantioenriched sulfones I [R1 = Me, Ph, 2-thienyl, etc.; R2 = Me, n-Bu, Bn, etc.; Ar = 4-MeOOCC6H4, 2-methoxy-pyridin-5-yl, 2-naphthyl, etc.] was reported. The reaction tolerated a variety of functional groups under mild reaction conditions, which complements current methods. The utility of this work was demonstrated by facile late-stage functionalization of com. drugs.5-Bromo-2-chloropyridine(cas: 53939-30-3Formula: C5H3BrClN) was used in this study.

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Formula: C5H3BrClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem