Month: December 2022

Ito, Satoshi published the artcileElectrochemical fluorination of (arylthio)methyl carboxylates and γ-phenylthio-γ-butyrolactone derivative, Computed Properties of 107263-95-6, the publication is Journal of the Electrochemical Society (2021), 168(6), 065502, database is CAplus.

Electrochem. fluorination of various (arylthio)methyl carboxylates was carried out in aprotic organic solvents containing poly(HF) salts to provide the corresponding O-fluoromethyl carboxylates in good to moderate yield. Electrochem. fluorination of a cyclic analog, a γ-phenylthio-γ-butyrolactone derivative was also achieved under ultrasonication to give the corresponding 4-fluorinated product in moderate yield.

Journal of the Electrochemical Society published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Computed Properties of 107263-95-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

den Hertog, H. J. published the artcileDerivatives of pyridine and quinoline. LXXXIX. Derivatives of pyridine 1-oxide. IV. Directive influence of the 1-oxide group during the nitration of derivatives of pyridine 1-oxide, Computed Properties of 18437-58-6, the publication is Recueil des Travaux Chimiques des Pays-Bas et de la Belgique (1951), 591-9, database is CAplus.

3-Ethoxypyridine (I) is converted to 3-ethoxypyridine I-oxide phthalate (II), m. 83.5-4.5°, with o-HO₂CC₆H₄CO₃H in Et₂O. II with fuming HNO₃ and H₂SO₄ yields 3-ethoxy-4-nitropyridine 1-oxide (III), m. 134-5°, which with Fe powder in HOAc gives 3-ethoxy-4-aminopyridine (picrate, m. 194-5°; mono-Ac derivative, m. 112.5-13.0°). Oxidation and nitration of 2-ethoxypyridine yields g-ethoxy-4-nitropyridine 1-oxide, m. 132.5-3.5°, which was reduced to 4-amino-2-ethoxypyridine, m. 88-9° forms a mono-Ac derivative, m. 105-5.5°, whose picrate m. 161-2°. The mono-Ac derivative of 2-amino-3-ethoxypyridine (IV) is prepared from IV and ketene, while the di-Ac derivative, m. 57.5-8.0°, is obtained from IV with Ac₂O at 215°. 2-Bromopyridine on oxidation and nitration yields 2-bromo-4-nitropyridine 1-oxide, m. 145.5-6.0°, reduced to 4-amino-2-bromopyridine, m. 95-7°. 2-Methylpyridine treated as above gives 2-methylpyridine 1-oxide phthalate, m. 115-16°, which on nitration yields 2-methyl-4-nitropyridine 1-oxide, m. 156-6.5°, reduced to 2-methyl-4-aminopyridine, m. 95.5-6°.

Recueil des Travaux Chimiques des Pays-Bas et de la Belgique published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Computed Properties of 18437-58-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Tanaka, Shunitz published the artcileMigration behavior of niacin derivatives in capillary electrophoresis, Related Products of pyridine-derivatives, the publication is Journal of Chromatography A (1995), 718(1), 233-7, database is CAplus.

The migration behavior of niacin derivatives was investigated by capillary zone electrophoresis (CZE) and micellar electrokinetic chromatog. (MEKC). When the pH of the buffer solution is lower than the pK_a of the pyridine ring in the niacin derivatives, they are pos. charged by protonation on the pyridine ring and migrate electrophoretically. The mobilities of niacin derivatives in CZE were controlled by the pH of the migrating buffer. Good separation of 13 niacin derivatives was achieved at pH 2.8. Further, to shorten the anal. time and to achieve a more complete separation, an investigation by MEKC using SDS micelles was performed. All 13 niacin derivatives were eluted within 30 min and a satisfactory separation was achieved.

Journal of Chromatography A published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C8H5F3N4, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Nagano, Koichi published the artcileSynthesis of functional heteroaromatic compounds. Synthesis of viologen derivatives. I, Name: 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, the publication is Aromatikkusu (1988), 40(5/6), 144-9, database is CAplus.

Viologens I (R = Me, halogen) were prepared by the reaction of N,N‘-bis(2,4-dinitrophenyl)-4,4’-bipyridinium salts with substituted anilines. The polarog. behavior of I at a dropping Hg electrode was studied in H₂O. I embedded in PVP matrix indicated rapid reversible photoreductions The effect of the substituents on the photochromic behavior of I was also discussed.

Aromatikkusu published new progress about 47369-00-6. 47369-00-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Salt,Benzene,Organic ligands for MOF materials,Nitrogen containing MOF ligands,Nitrogen containing MOF ligands, name is 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, and the molecular formula is C22H18Cl2N2, Name: 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Frischmuth, Annette published the artcilePreparation of Functionalized Indoles and Azaindoles by the Intramolecular Copper-Mediated Carbomagnesiation of Ynamides, SDS of cas: 39856-58-1, the publication is Angewandte Chemie, International Edition (2013), 52(38), 10084-10088, database is CAplus and MEDLINE.

The authors report a mild and general one-pot preparation of indoles and azaindoles using a 5-endo-dig copper-mediated intramol. carbometalation of magnesiated derivatives, which lead to cuprated intermediates that, after quenching with various electrophiles, afford functionalized N-heterocycles. Thus, 2-bromo-4-fluoroaniline reacted with PhSO₂Cl to give the N-phenylsulfonyl derivative, which was alkynylated with phenyl[(trimethylsilyl)ethynyl]iodonium triflate to give alkyne derivative I (R = F, CF₃, CN, CO₂CMe₃). I was then treated with iso-PrMgCl·LiCl to give the Mg reagents that were cyclized with electrophiles using a catalytic amount of CuCN·2LiCl to produce the corresponding indoles II [R¹ = CH₂C(CO₂Et):CH₂, COC₆H₄Cl-3, cyclopropylcarbonyl, 2-cyclohexenyl, COC₆H₄Me-4] in 62-93% yield.

Angewandte Chemie, International Edition published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, SDS of cas: 39856-58-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Fischer, E. published the artcileStereochemical studies of heterocyclic compounds. XII. Crystal and molecular structure of 1-(2-amino-1-cyano-2-thioethenyl)pyridinium ylides, Related Products of pyridine-derivatives, the publication is Journal fuer Praktische Chemie (Leipzig) (1983), 325(2), 261-8, database is CAplus.

E/Z Isomerization and hindered rotation of the pyridine ring were examined in I (R = Me, R¹ = Et). The former process had ΔG^* = 67 kJ/mol; the latter had ΔG^* = 46 kJ/mol. Crystallog. data, bond lengths, and bond angles were determined for I (R = H, R¹ = Ph); both E and Z isomers exists in the crystal. The C:C double bond is considerably longer than those in some olefins.

Journal fuer Praktische Chemie (Leipzig) published new progress about 17281-59-3. 17281-59-3 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitrile,Salt, name is 1-(Cyanomethyl)pyridin-1-ium chloride, and the molecular formula is C7H7ClN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Oishi, Michio published the artcileEffect of L-cysteine on α-amylase production and nucleic acid metabolism in Bacillus subtilis, Product Details of C23H20BN, the publication is Journal of General and Applied Microbiology (1963), 9(3), 337-41, database is CAplus.

In B. subtilis, 10^-4M L-cysteine caused an almost complete inhibition of adenine incorporation into ribo- and DNAs and 2 × 10^-5M amounts suppressed α-amylase production to 80-90% of the controls. The latter inhibition was reversed by unidentified compounds in yeast extract

Journal of General and Applied Microbiology published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Product Details of C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Okamura, H. published the artcileEcotoxicity of the degradation products of triphenylborane pyridine (TPBP) antifouling agent, Category: pyridine-derivatives, the publication is Chemosphere (2009), 74(9), 1275-1278, database is CAplus and MEDLINE.

Triphenylborane pyridine (TPBP) is an alternative to organotin antifouling compounds This work aimed to identify the unknown Peak #1, and to evaluate the ecotoxicity of TPBP and its degradation products. Peak #1 was produced from TPBP dissolved in acetonitrile under UV-A photolysis using a high-pressure Hg lamp. The Peak #1 fraction was purified using 2-step column chromatog. from a TPBP-acetonitrile solution The major compound of the fraction was identified as being biphenyl from the ¹H NMR and ¹³C NMR spectra. The ecotoxicity of 4 degradation products (diphenylborane hydroxide, phenylborane dihydroxide, phenol, and biphenyl) and TPBP towards 2 marine planktons were assessed. The 48 h LC₅₀ values of the crustacean, Artemia salina, were 0.13 mg L^-1 for TPBP, 14 mg L^-1 for biphenyl, 17 mg L^-1 for phenol, and >50 mg L^-1 for the other degradation products. The 72 h EC₅₀ values of the diatom, Skeletonema costatum, were 0.0022 mg L^-1 for TPBP, 1.2 mg L^-1 for biphenyl, and >2 mg L^-1 for the other degradation products. Thus, the ecotoxicity of biphenyl and the other degradation products were not high compared to the parent compound, TPBP.

Chemosphere published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Imai, Yoshitane published the artcileFormation of chiral charge-transfer complex with axially chiral 1,1′-bi-2-naphthol and viologen derivatives, Computed Properties of 47369-00-6, the publication is Tetrahedron Letters (2006), 47(21), 3603-3606, database is CAplus.

By using three types of viologen derivatives, we synthesized chiral charge-transfer (CT) complexes with an axially chiral 1,1′-bi-2-naphthol mol. and successfully controlled the crystal structure and inclusion ability of the third component by changing the viologens.

Tetrahedron Letters published new progress about 47369-00-6. 47369-00-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Salt,Benzene,Organic ligands for MOF materials,Nitrogen containing MOF ligands,Nitrogen containing MOF ligands, name is 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, and the molecular formula is C22H18Cl2N2, Computed Properties of 47369-00-6.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Imai, Yoshitane published the artcileCharge-transfer host system composed of 9,10-bis(3,5-dihydroxyphenyl)anthracene and methylviologen, Product Details of C22H18Cl2N2, the publication is Tetrahedron (2009), 65(18), 3740-3744, database is CAplus.

By using 9,10-bis(3,5-dihydroxyphenyl)anthracene as an electron donor and 1,1′-dimethyl-4,4′-bipyridinium dichloride as an electron acceptor, a spontaneously resolved charge-transfer (CT) complex is formed. This CT complex can include n-alkyl alc. mols. as guests, and the DRS of this CT complex change with the type of component guest mols.

Tetrahedron published new progress about 47369-00-6. 47369-00-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Salt,Benzene,Organic ligands for MOF materials,Nitrogen containing MOF ligands,Nitrogen containing MOF ligands, name is 1,1′-Diphenyl-[4,4′-bipyridine]-1,1′-diium chloride, and the molecular formula is C22H18Cl2N2, Product Details of C22H18Cl2N2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem