Month: December 2022

Zhang, Zixu published the artcileGuanidine-functionalized graphene to improve the antifouling performance of boron acrylate polymer, Formula: C23H20BN, the publication is Progress in Organic Coatings (2021), 106396, database is CAplus.

A series of antifouling composite coatings based on guanidine-functionalized graphene (GNG) and self-polishing boron acrylate polymer (BAP) were prepared Compared to graphene oxide, GNG had more wrinkles on its surface and was more uniformly distributed in the interior and on the surface of BAP, resulting in the tight binding of inorganic and organic compounds at the interface. The BAP/GNG composite coatings exhibited excellent algae anti-adhesion performance. Specifically, the inhibition rate of Phaeodactylum tricornutum reached 99.2%, and high antibacterial rates of up to 94.2% and 95% were obtained for Escherichia coli and Staphylococcus aureus, resp. This performance is ascribed to the polishing of BPA, exposing the guanidine-functionalized graphene on the surface. On one hand, as a filler, the prepared guanidine-functionalized graphene improved the antifouling ability by adjusting the hydrolysis rate of the antifouling coating. On the other hand, the exposure of guanidine-functionalized graphene and the hydrolysis of the polymer matrix enhanced the antifouling capability. BAP/GNG shows promise as an antifouling coating with potential applications in marine antifouling.

Progress in Organic Coatings published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C9H9ClN2, Formula: C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Li, Yakun published the artcileSynthesis of Amphiphilic Acrylate Boron Fluorinated Polymers with Antifouling Behavior, Category: pyridine-derivatives, the publication is Industrial & Engineering Chemistry Research (2019), 58(19), 8016-8025, database is CAplus.

We constructed two kinds of amphiphilic acrylate boron fluorinated polymers (ABFPs) with backbones comprising acrylate fluorinated polymers (AFPs) and side chains comprising hydrolyzable pyridine-phenylborane functional groups. We determined the hydrolysis rates of the ABFPs by measuring their weight loss ratios. The ABFPs with shorter fluorinated side chains had higher rates of hydrolysis. We investigated and confirmed the amphiphilic and antifouling behavior of the ABFPs, using XPS and surface wettability analyses. During immersion for 90 days in the Bohai Sea of China, the ABFP coatings exhibited good antifouling performance. We also assessed the environmental characteristics of the ABFP coatings by determining the COD (COD) and growth rate of diatoms on their surfaces. The present study provides new insight into the development of environmentally friendly ABFPs with desirable antifouling properties.

Industrial & Engineering Chemistry Research published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Li, Yakun published the artcileFabrication and antifouling behavior research of self-healing lubricant impregnated films with dynamic surfaces, Related Products of pyridine-derivatives, the publication is Colloids and Surfaces, A: Physicochemical and Engineering Aspects (2019), 123865, database is CAplus.

To repel the unwanted fouling organisms, various strategies were developed. During these methods, most static antifouling surfaces can not effectively deter the adhesion of marine biofouling in the long term. In this study, self-healing acrylate boron fluorinated polymer films (SABFPs) with dynamic surfaces were facilely prepared by mixing perfluoropolyether (PFPE) lubricant with acrylate boron fluorinated polymer (ABFP) by ultrasonic dispersion. The self-healing mechanism was investigated by analyzing the film thickness change and the distribution of elements under different conditions. Weight loss measurement demonstrated the self-replenishing lubricant and self-polishing polymer surfaces constitute the dynamic surfaces, which reduce the adhesion of fouling organisms in a significant extent. Moreover, the prepared samples exhibited outstanding abrasion performance. Advantageously, this study provided a simple method for preparing marine antifouling films under environmentally friendly conditions.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Li, Yakun published the artcileAntifouling behavior of self-renewal acrylate boron polymers with pyridine-diphenylborane side chains, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate, the publication is New Journal of Chemistry (2018), 42(24), 19908-19916, database is CAplus.

Currently, most high-performance tributyltin (TBT)-free antifouling paints contain cuprous oxide (Cu₂O) in their formulations, leading to a serious challenge to the marine environment and ecosystem. In this study, non-metal acrylate boron polymers (ABPs) were synthesized using acrylate acid polymers (AAPs) as the backbone and a pyridine-Ph borane compound as the side chain with hydrolyzable functional groups. The antifouling mechanism of ABPs researched by XPS and EDS indicated that the antifouling performance of ABPs was realized by the hydrolysis of hydrophobic di-Ph borane pyridine side groups. The results of diatom anti-setting test showed that fewer or no algae cells were attached on the surfaces of ABPs with higher contents of hydrophobic di-Ph borane pyridine side groups. The growth rates of algae suspension solutions containing ABPs were close to that of the blank solution without ABPs. Antifouling paints made of ABPs showed excellent antifouling performances in the Yellow Sea of China. This study provides new insights into the development of ABPs with desirable antifouling properties and environmental friendliness.

New Journal of Chemistry published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Yuan, Yanbing published the artcileRapid detection of illegally added nifedipine in Chinese traditional patent medicine by surface-enhanced Raman spectroscopy., Related Products of pyridine-derivatives, the publication is Analytical sciences : the international journal of the Japan Society for Analytical Chemistry (2022), 38(2), 359-368, database is MEDLINE.

Nifedipine is an antihypertensive chemical. The illegal addition of this chemical into Chinese traditional patent medicine (CTPM) is unstandardized and lacks regulation. It could bring serious side effects to patients, causing various symptoms. Therefore, accurate detection of nifedipine is very important for human health and the prevention of illegal additives. Surface-enhanced Raman spectroscopy (SERS) is a fast and sensitive fingerprint spectroscopic technique, which has been shown to be promising in drug detection. In this study, nifedipine in CTPM was determined qualitatively and quantitatively with SERS. Linear relationships between the concentrations of nifedipine and the intensities of the characteristic peaks were established. The results showed a linear relationship within the concentration range of 0.5-10 mg/L, and the lowest detectable concentration of nifedipine in CTPM was 0.1 mg/L (equivalent to 0.03% doping of nifedipine in CTPM). This method has shown a great potential in the detection of drugs illegally added to CTPM.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry published new progress about 21829-25-4. 21829-25-4 belongs to pyridine-derivatives, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C12H9N3O4, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Li, Chaomin published the artcileRapid construction of imidazopyridines from ortho-haloaminopyridines, Computed Properties of 39856-58-1, the publication is Tetrahedron Letters (2016), 57(25), 2708-2712, database is CAplus.

A practical strategy for the preparation of imidazopyridine derivatives from ortho-haloaminopyridines using a two-step C-N coupling/cyclization reaction sequence was developed. This procedure provides rapid and efficient access to many medicinally interesting imidazopyridine compounds and related imidazopyrazine/purine heterocycles.

Tetrahedron Letters published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Computed Properties of 39856-58-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Winther-Jensen, Bjorn published the artcileVapor Phase Polymerization of Pyrrole and Thiophene Using Iron(III) Sulfonates as Oxidizing Agents, Application of Pyridine-3-sulfonic acid, the publication is Macromolecules (2004), 37(16), 5930-5935, database is CAplus.

Vapor phase polymerization is a versatile technique that can be used to obtain highly conducting coatings of conjugated polymer on both conducting and nonconducting substrates. This is demonstrated here by preparation of polypyrrole, polybithiophene, and polyterthiophene, coatings that otherwise must be prepared electrochem. in order to achieve the desired high conjugation. The method is based on the use of organic ferric sulfonates as oxidant as these salts easily form smooth, noncrystalline films. By proper choice of the sulfonate anion, the oxidizing power of the ferric salt can be varied over a wide range. The described technique can easily be adapted to different patterning techniques.

Macromolecules published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C14H20BClO2, Application of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Dumas, Megan E. published the artcileDual inhibition of Kif15 by oxindole and quinazolinedione chemical probes, Category: pyridine-derivatives, the publication is Bioorganic & Medicinal Chemistry Letters (2019), 29(2), 148-154, database is CAplus and MEDLINE.

The mitotic spindle is a microtubule-based machine that segregates a replicated set of chromosomes during cell division. Many cancer drugs alter or disrupt the microtubules that form the mitotic spindle. Microtubule-dependent mol. motors that function during mitosis are logical alternative mitotic targets for drug development. Eg5 (Kinesin-5) and Kif15 (Kinesin-12), in particular, are an attractive pair of motor proteins, as they work in concert to drive centrosome separation and promote spindle bipolarity. Furthermore, we hypothesize that the clin. failure of Eg5 inhibitors may be (in part) due to compensation by Kif15. In order to test this idea, we screened a small library of kinase inhibitors and identified GW108X, an oxindole that inhibits Kif15 in vitro. We show that GW108X has a distinct mechanism of action compared with a com. available Kif15 inhibitor, Kif15-IN-1 and may serve as a lead with which to further develop Kif15 inhibitors as clin. relevant agents.

Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Park, Hojoon published the artcileLigand-Enabled, Palladium-Catalyzed β-C(sp³)-H Arylation of Weinreb Amides, Category: pyridine-derivatives, the publication is ACS Catalysis (2018), 8(10), 9292-9297, database is CAplus and MEDLINE.

Authors report the development of Pd(II)-catalyzed C(sp³)-H arylation of Weinreb amides. Both the inductive effect and the potential bidentate coordination mode of the Weinreb amides pose a unique challenge for this reaction development. A pyridinesulfonic acid ligand is designed to accommodate the weak, neutral-coordinating property of Weinreb amides by preserving the cationic character of Pd center through zwitterionic assembly of Pd/ligand complexes. D. functional theory (DFT) studies of the C-H cleavage step indicate that the superior reactivity of 3-pyridinesulfonic acid ligand, compared to Ac-Gly-OH and ligandless conditions, originates from the stabilization of overall substrate-bound Pd species.

ACS Catalysis published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Shirkhedkar, Atul A. published the artcileExploring an experimental combination of analytical quality by design and green analytical chemistry approaches for development of HPTLC densitometric protocol for the analysis of barnidipine hydrochloride, Application of Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, the publication is Biomedical Chromatography (2022), 36(1), e5244, database is CAplus and MEDLINE.

An exptl. combination of anal. quality by design and green anal. chem. approaches is introduced to develop an high-performance thin-layer chromatog. (HPTLC) approach to quantify barnidipine hydrochloride in the pharmaceutical matrix. The anal. quality by design approach was introduced to green anal. chem. to enhance protocol knowledge while ensuring efficiency and reducing environmental impacts, energy consumption and analyst visibility. This anal. approach was systematically addressed by exploring failure mode effect anal., risk assessment and optimization design. Subsequently, a screening of primary variables was performed to select the aptest proportion of solvents in the mobile phase resulting from the principles of green anal. chem. Failure mode effect anal. and a risk assessment study were attempted to estimate the critical method parameters (CMPs). The influence of the CMPs on critical anal. attributes, i.e. retention factor and peak area, was assessed through a screening design. A response surface methodol. was then executed for the critical anal. attributes as a concern of the determined CMPs, and the conditions for excellent resolution were determined using a desirability procedure. The established protocol was validated in compliance with the International Conference on Harmonization guideline Q2(R1) and showed excellent specificity and sensitivity.

Biomedical Chromatography published new progress about 21829-25-4. 21829-25-4 belongs to pyridine-derivatives, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C12H10O4S, Application of Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem