Day: January 4, 2023

Production and purification of an extracellular lipolytic enzyme using ionic liquid-based aqueous two-phase systems was written by Ventura, Sonia Patricia Marques;Freire de Barros, Rafael Lemos;Barbosa, Jose Murillo de Pinho;Soares, Cleide Mara Faria;Lima, Alvaro Silva;Coutinho, Joao Araujo Pereira. And the article was included in Green Chemistry in 2012.Recommanded Product: 1-Butyl-3-methylpyridinium Chloride This article mentions the following:

The ability of ionic liquid-based aqueous two-phase systems (ATPS) to purify lipase produced by fermentation is here evaluated and compared against conventional PEG-based ATPS systems. Four ionic liquids, chosen after screening of a larger number of ionic liquids are evaluated, with the maximum purification and higher recovery being obtained for the systems based on [C₈mim]Cl. It is shown that IL-based ATPS have a performance superior to PEG-based ATPS for the purification of this enzyme. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3Recommanded Product: 1-Butyl-3-methylpyridinium Chloride).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 1-Butyl-3-methylpyridinium Chloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reinforcing Supramolecular Bonding with Magnetic Dipole Interactions to Assemble Dynamic Nanoparticle Superlattices was written by Santos, Peter J.;MacFarlane, Robert J.. And the article was included in Journal of the American Chemical Society in 2020.Recommanded Product: 1075-62-3 This article mentions the following:

Assembling superparamagnetic particles into ordered lattices is an attractive means of generating new magnetically responsive materials, and is commonly achieved by tailoring interparticle interactions as a function of the ligand coating. However, the inherent linkage between the collective magnetic behavior of particle arrays and the assembly processes used to generate them complicates efforts to understand and control material synthesis. Here, the authors use a synergistic combination of a chem. force (hydrogen bonding) and magnetic dipole coupling to assemble polymer-brush coated superparamagnetic Fe oxide nanoparticles, where the relative strengths of these interactions can be tuned to reinforce one another and stabilize the resulting superlattice phases. The authors can precisely control both the dipole-dipole coupling between nanoparticles and the strength of the ligand-ligand interactions by modifying the interparticle spacing through changes to the polymer spacer between the hydrogen bonding groups and the nanoparticles’ surface. This results in modulation of the materials’ blocking temperature, as well as the stabilization of a unique superlattice phase that only exists when magnetic coupling between particles is present. Using magnetic interactions to affect nanoparticle assembly in conjunction with ligand-mediated interparticle interactions expands the potential for synthesizing predictable and controllable nanoparticle-based magnetic composites. In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Recommanded Product: 1075-62-3).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·molâˆ? in pyridine vs. 150 kJ·molâˆ? in benzene). Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Recommanded Product: 1075-62-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mixed micelles of n-alkylpyridinium bromide and Triton X-100 in aqueous media was written by Parihar, Shailendra Kumar;Goswami, Ashok K.. And the article was included in International Journal of Chemical Sciences in 2008.Product Details of 104-73-4 This article mentions the following:

The mixed micellization process of binary mixtures formed by n-alkylpyridinium bromide including tetradecylpyridinium bromide (C₁₄PB), dodecylpyridnium bromide (C₁₂PB), decylpyridinium bromide (C₁₂PB) and tert-octylphenylpolyoxyethylene ether (Triton X-100) was examined, by surface tension method. The mixed CMC (C*) values were determined and in all cases a neg. deviation from the ideal behavior was observed However, the interaction parameter (β) as given by regular solution theory (RST) was found to be dependent on the micellar composition In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Product Details of 104-73-4).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Product Details of 104-73-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Proton magnetic resonance spectra of pyridine 1-oxides and their conjugate acids was written by Abramovitch, Rudolph A.;Davis, John Bernard. And the article was included in Journal of the Chemical Society [Section] B: Physical Organic in 1966.Category: pyridine-derivatives This article mentions the following:

The proton magnetic resonance spectra of eleven pyridine 1-oxides (I) were measured in CCl4, D2O, and 18N deuteriosulfuric acid solution (corresponding to the neutral, hydrogen-bonded, and O-protonated species). The average downfield shifts for the α-, β-, and γ-proton lines have been calculated and the results are discussed. Electron distributions and coupling constants are compared with those of the corresponding pyridines and pyridinium salts. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Category: pyridine-derivatives).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Cobalt-catalyzed C4-selective direct alkylation of pyridines was written by Andou, Takashi;Saga, Yutaka;Komai, Hirotomo;Matsunaga, Shigeki;Kanai, Motomu. And the article was included in Angewandte Chemie, International Edition in 2013.SDS of cas: 27876-24-0 This article mentions the following:

A catalyst for the atom-economical C4-selective direct alkylation of pyridines is developed. A catalytic amount of CoBr₂ in combination with LiBEt₃H gave branched adducts from styrene derivatives, and linear adducts from aliphatic alkenes. The high catalyst turnover numbers (up to 3440; s/c = 4000) observed in the reaction with styrene are noteworthy. In the experiment, the researchers used many compounds, for example, 4-Hexylpyridine (cas: 27876-24-0SDS of cas: 27876-24-0).

4-Hexylpyridine (cas: 27876-24-0) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol� in pyridine vs. 150 kJ·mol� in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. SDS of cas: 27876-24-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of 6-hydrazino(alkylhydrazino)-4-methyl-2-chloronicotinonitriles was written by Dmitrieva, I. G.;Dyadyuchenko, L. V.;Konyushkin, L. D.;Kaigorodova, E. A.. And the article was included in Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya in 2006.COA of Formula: C7H5ClN2 This article mentions the following:

With the help of Nuclear Overhauser Effect spectroscopy it became possible to specify the structure of 6-hydrazino(alkylhydrazino)-4-methyl-2-chloronicotinonitriles I (R = H, Me, Et). In the experiment, the researchers used many compounds, for example, 2-Chloro-4-methylpyridine-3-carbonitrile (cas: 65169-38-2COA of Formula: C7H5ClN2).

2-Chloro-4-methylpyridine-3-carbonitrile (cas: 65169-38-2) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.COA of Formula: C7H5ClN2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Improvement of the synthesis process of benzobromarone was written by Huang, Li-rong;Bai, Yue-fei;Chen, Hong;Yu, Yong-qi. And the article was included in Liaoning Huagong in 2014.Synthetic Route of C5H6ClN This article mentions the following:

Friedel-Crafts acylation of 2-ethylbenzofuran with 4-methoxybenzoyl chloride was carried out in dichloromethane or chloroform, then demethylation of the product and pyridine hydrochloride was carried out, at last benzobromarone was obtained via bromination of the product and bromide, total yield reached 55%�0%. The process is characterized with low toxicity, good product quality and is suitable for industrial production In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Synthetic Route of C5H6ClN).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Synthetic Route of C5H6ClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Radical-Based Regioselective C-H Functionalization of Electron-Deficient Heteroarenes: Scope, Tunability, and Predictability was written by O’Hara, Fionn;Blackmond, Donna G.;Baran, Phil S.. And the article was included in Journal of the American Chemical Society in 2013.Quality Control of 2-Isopropylpyridine This article mentions the following:

Radical addition processes can be ideally suited for the direct functionalization of heteroaromatic bases, yet these processes are only sparsely used due to the perception of poor or unreliable control of regiochem. A systematic investigation of factors affecting the regiochem. of radical functionalization of heterocycles using alkylsulfinate salts revealed that certain types of substituents exert consistent and additive effects on the regioselectivity of substitution. This allowed us to establish guidelines for predicting regioselectivity on complex π-deficient heteroarenes, including pyridines, pyrimidines, pyridazines, and pyrazines. Since the relative contribution from opposing directing factors was dependent on solvent and pH, it was sometimes possible to tune the regiochem. to a desired result by modifying reaction conditions. This methodol. was applied to the direct, regioselective introduction of iso-Pr groups into complex, biol. active mols., such as diflufenican (I; R = H â†?R = iso-Pr) and nevirapine (II; R = H â†?R = iso-Pr). In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Quality Control of 2-Isopropylpyridine).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Quality Control of 2-Isopropylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Biodegradability of 27 pyrrolidinium, morpholinium, piperidinium, imidazolium and pyridinium ionic liquid cations under aerobic conditions was written by Neumann, Jennifer;Steudte, Stephanie;Cho, Chul-Woong;Thoeming, Jorg;Stolte, Stefan. And the article was included in Green Chemistry in 2014.Related Products of 17281-59-3 This article mentions the following:

The chem. and thermal stability of ionic liquids (ILs) makes them interesting for a large variety of applications in nearly all areas of the chem. industry. However, this stability is often reflected in their recalcitrance towards biodegradation, which comes with the risk of persistence when they are released into the environment. The authors carried out a systematic study of the biodegradability of pyrrolidinium, morpholinium, piperidinium, imidazolium and pyridinium-based IL cations substituted with different alkyl or functionalized side chains and using halide counterions. The authors examined their primary degradability by specific anal. and/or their ultimate biodegradability using BOD tests according to OECD guideline 301F. Biol. transformation products were studied using mass spectrometry. A comparison of the biodegradation potential of these ILs shows that for all five head groups, representatives can be found that are readily or inherently biodegradable, thus permitting the structural design of ILs with a reduced environmental hazard. In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3Related Products of 17281-59-3).

1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Related Products of 17281-59-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Effect of methyl substituent on the ultraviolet spectra of some aza aromatics was written by Das, Bimal Kumar. And the article was included in Journal of the Indian Chemical Society in 1968.Electric Literature of C7H9NO This article mentions the following:

The shift in the longest wavelength absorption band of Me substituted pyrazine, pyrimidine, pyridazine, and pyridine 1-oxide is theoretically calculated The calculation shows fair agreement with exptl. determined values. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Electric Literature of C7H9NO).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Electric Literature of C7H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem