Day: January 5, 2023

Oxidative valorization of lignin into valuable phenolics: Effect of acidic and basic catalysts and reaction parameters was written by Kumar, Avnish;Biswas, Bijoy;Kaur, Ramandeep;Krishna, Bhavya B.;Thallada, Bhaskar. And the article was included in Bioresource Technology in 2021.SDS of cas: 28020-37-3 This article mentions the following:

The aromatic nature of lignin makes it a good source for the production of numerous platform chems. The valorization of lignin into valuable compounds depends upon the type of bonds and functionality present in lignin. Here, we have studied the depolymerization of rice straw alkali lignin in N₂ and O₂ with acidic (ZSM-5), basic (MgO) catalyst and with their mixtures (1:1, 3:7 and 7:3). The effect of hydrogen peroxide on lignin depolymerization was also examined Maximum yield of bio-oil (50 wt%) was obtained with pure ZSM-5 and 1 mL hydrogen peroxide in nitrogen atm., while maximum conversion (60%) was observed in oxygen environment during the non-catalytic depolymerization of lignin. Bio-oil characterization through GC-MS showed maximum selectivity towards 2-methoxy-4-vinylphenol with 38.5 area% in the bio-oil of ZSM-5-N₂. The bio-oils have also been characterized using ¹H NMR, FT-IR and GC-MS. In the experiment, the researchers used many compounds, for example, 3-Amino-2,6-dimethoxypyridine (cas: 28020-37-3SDS of cas: 28020-37-3).

3-Amino-2,6-dimethoxypyridine (cas: 28020-37-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.SDS of cas: 28020-37-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Micellar, interfacial and fluorescence investigation on binary mixtures of dodecyl cationic surfactants in aqueous media was written by Moulins, Jonathan R.;Harris, Adam A.;Dean, Rebecca K.;Moore, Stephanie A.;Palepu, Rama M.. And the article was included in Colloids and Surfaces, A: Physicochemical and Engineering Aspects in 2007.Product Details of 104-73-4 This article mentions the following:

The critical micelle concentration (CMC) of binary mixtures of C₁₂-triphenyl phosphonium, pyridinium and tri-Me ammonium bromides were determined employing conductometry, surface tensiometry and fluorescence techniques. Binary mixtures of C₁₂ phosphonium bromide with C₁₂ tri-Me ammonium and pyridinium bromide surfactants exhibited 2nd breaks due to the structural micellar transition, and are supported by conductometric and fluorometric methods. The values of surface excess, min. area of the C₁₂ surfactants at the cmc and Gibbs energy of adsorption were evaluated. The ideality/nonideality of the mixing was analyzed using regular solution theory (RST) to obtain the composition of the mixed micelle and the interaction parameter (β ^m) to evaluate the strength of interactions of surfactants in the mixed micelles. The tensiometric measurements were also analyzed to obtain the interaction parameter (β ^σ) for the mixed monolayer at the air/water interface. Activity coefficients and the excess free energy of mixing were also determined In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Product Details of 104-73-4).

1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Product Details of 104-73-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of Molybdenum and Tungsten Alkylidene Complexes That Contain the 2,6-Bis(2,4,6-triisopropylphenyl)phenylimido (NHIPT) Ligand was written by Axtell, Jonathan C.;Schrock, Richard R.;Muller, Peter;Hoveyda, Amir H.. And the article was included in Organometallics in 2015.Related Products of 628-13-7 This article mentions the following:

Mo and W alkylidene complexes that contain the sterically demanding hexaisopropylterphenylimido ligand, N-2,6-(2,4,6-i-Pr₃C₆H₂)₂C₆H₃ (NHIPT), were prepared from Mo(N-t-Bu)₂Cl₂(1,2-dimethoxyethane) or W(N-t-Bu)₂Cl₂(pyridine)₂, employing tert-butylimido ligands as sacrificial proton acceptors. These complexes include M(NHIPT)(CH-t-Bu)Cl₂ (M = Mo, W), Mo(NHIPT)(CH-t-Bu)(pyrrolide)₂, and Mo(NHIPT)(CH-t-Bu)(pyrrolide)(OC₆F₅)(MeCN). In all cases only anti alkylidene isomers are observed in solution, as a consequence of the steric demands of the NHIPT ligand. An x-ray structure of W(NHIPT)(CH-t-Bu)Cl₂ showed it to be a monomer with a disordered alkylidene that is 86% in the anti configuration and 14% in the syn configuration. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Related Products of 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Related Products of 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Isotruxene-based porous polymers as efficient and recyclable photocatalysts for visible-light induced metal-free oxidative organic transformations was written by Zhang, Haowen;Zhou, Cen;Zheng, Ying;Zhang, Xiao. And the article was included in Green Chemistry in 2021.Application In Synthesis of Pyridin-4-ol This article mentions the following:

Two new isotruxene-based porous polymers were prepared and demonstrated to be highly efficient, metal-free heterogeneous photocatalysts for oxidative transformations using air as the mild oxidant under visible-light irradiation Both catalysts show excellent recyclability. In addition, the reactions can be performed in water, further indicating the greenness of this method. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application In Synthesis of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application In Synthesis of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Supramolecular assembly-induced enhanced emission of electrospun nanofibers was written by Cheng, Chih-Chia;Wang, Yeh-Sheng;Chang, Feng-Chih;Lee, Duu-Jong;Yang, Li-Chih;Chen, Jem-Kun. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.HPLC of Formula: 1075-62-3 This article mentions the following:

A nucleobase-assembled supramol. nanofiber is capable of forming network-like polymeric clusters through complementary hydrogen-bonding interactions. It behaves as an effective chromophore that greatly enhances the light emission efficiency of fluorescent fibers, reaching up to three times higher efficiency than the control samples. In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3HPLC of Formula: 1075-62-3).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.HPLC of Formula: 1075-62-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Spectral, thermal and DFT studies of novel nickel(II) complexes of 2-benzoylpyridine-N⁴-methyl-3- thiosemicarbazone: Crystal structure of a square planar azido-nickel(II) complex was written by Jayakumar, K.;Seena, E. B.;Kurup, M. R. Prathapachandra;Kaya, Savas;Serdaroglu, Goncagul;Suresh, E.;Marzouki, Riadh. And the article was included in Journal of Molecular Structure in 2022.Reference of 91-02-1 This article mentions the following:

Novel six Ni(II) complexes of an NNS donor 2-benzoylpyridine-N⁴-methyl-3- thiosemicarbazone(HL) were synthesized and characterized. Various physicochem. techniques are applied for the study of the coordination behavior of the thiosemicarbazone to the nickel center. In all the complexes, thiosemicarbazone is coordinated in the thiolate form. A four coordinated Ni(II) complex [NiLN₃] is crystallized and its mol. and crystal structures are determined by single-crystal x-ray crystallog. Single-crystal XRD reveals that the complex got crystallized in the monoclinic space group P2₁/n and nickel(II) has a square planar environment. Intramol. hydrogen bonding interactions make the complex more rigid and in the crystal lattice, the intermol. hydrogen bonding interactions generate a supramol. 1 D chain. The chem. reactivity behavior of the HL and six Ni(II) complexes was evaluated with the CAM-B3LYP quantum chem. calculations The validity of electronic structure principles like Maximum Hardness, Min. Polarizability, and Min. Electrophilicity Principle in the study is discussed. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Reference of 91-02-1).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Reference of 91-02-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Carboxylation of 2-hydroxypicolines was written by Weglinski, Zbigniew;Talik, Tadeusz. And the article was included in Roczniki Chemii in 1977.Recommanded Product: 65169-38-2 This article mentions the following:

Treatment of a mixture of 2-hydroxy-3-methylpyridine (I) and anhydrous K₂CO₃ with 55 atm CO₂ at 220° for 9 h gave 87% 2-hydroxy-3-methyl-5-pyridinecarboxylic acid (II). Carboxylation of the Na and K salts of I gave 49.5 and 53% II, resp. Similarly, 2-hydroxy-5-methyl-, 2-hydroxy-6-methyl-, and 2-hydroxy-4-methylpyridine gave 2-hydroxy-5-methyl-3-pyridinecarboxylic acid, 2-hydroxy-6-methyl-3-pyridinecarboxylic acid, and 2-hydroxy-4-methyl-5-pyridinecarboxylic acid, resp. The isomeric hydroxymethylpyridinecarboxylic acids were also prepared by hydrolysis of the corresponding isomeric chlorocyanopicolines. The latter were obtained from isomeric aminopicolines by successive nitration, hydroxylation, chlorination, reduction, and Sandmeyer cyanation. In the experiment, the researchers used many compounds, for example, 2-Chloro-4-methylpyridine-3-carbonitrile (cas: 65169-38-2Recommanded Product: 65169-38-2).

2-Chloro-4-methylpyridine-3-carbonitrile (cas: 65169-38-2) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 65169-38-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Determination of a new scale of ortho-steric parameters S⁰ from N-methylation of pyridines was written by Berg, Ulf;Gallo, Roger;Klatte, Gerd;Metzger, Jacques. And the article was included in Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) in 1980.Quality Control of 2-Isopropylpyridine This article mentions the following:

The kinetics of quaternization by MeI of 33 substituted pyridines, e.g. 2-ethylpyridine, were measured in MeCN at 30°. The relative rate constants obtained were similar to those observed in other polar aprotic solvents. The magnitude of steric effects observed for all ortho-substituents were estimated from the Broensted plot. A scale of ortho-steric parameters (S⁰) was proposed. No correlation was observed between S⁰ and the electronic effect of substituents. S⁰ Is not solvent dependent. The relative S⁰ values agree with other exptl. values of the steric size of the substituents. The S⁰ parameters are discussed in terms of substituent structure relative to the Taft-Kutter-Hansch E_s and Charton ν parameters. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Quality Control of 2-Isopropylpyridine).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Quality Control of 2-Isopropylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Enantioselective synthesis of tunable chiral pyridine-aminophosphine ligands and their applications in asymmetric hydrogenation was written by Liu, Youran;Chen, Fei;He, Yan-Mei;Li, Chenghao;Fan, Qing-Hua. And the article was included in Organic & Biomolecular Chemistry in 2019.Related Products of 644-98-4 This article mentions the following:

A small library of tunable chiral pyridine-aminophosphine ligands were enantioselectively synthesized based on chiral 2-(pyridin-2-yl)-substituted 1,2,3,4-tetrahydroquinoline scaffolds, which were obtained in high yields and with excellent enantioselectivities via Ru-catalyzed asym. hydrogenation of 2-(pyridin-2-yl)quinolines. The protocol features a wide substrate scope and mild reaction conditions, enabling scalable synthesis. These chiral P,N ligands were successfully applied in the Ir-catalyzed asym. hydrogenation of benchmark olefins and challenging seven-membered cyclic imines including benzazepines and benzodiazepines. Excellent enantio- and diastereoselectivity (up to 99% ee and >20 : 1 dr), and/or unprecedented chemoselectivity were obtained in the asym. hydrogenation of 2,4-diaryl-3H-benzo[b]azepines and 2,4-diaryl-3H-benzo[b][1,4]diazepines. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Related Products of 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Related Products of 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Rare-Earth-Catalyzed C-H Bond Addition of Pyridines to Olefins was written by Guan, Bing-Tao;Hou, Zhaomin. And the article was included in Journal of the American Chemical Society in 2011.Electric Literature of C8H11N This article mentions the following:

An efficient and general protocol for the ortho-alkylation of pyridines via C-H addition to olefins has been developed, using cationic half-sandwich rare-earth catalysts, which provides an atom-economical method for the synthesis of alkylated pyridine derivatives A wide range of pyridine and olefin substrates including α-olefins, styrenes, and conjugated dienes are compatible with the catalysts. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Electric Literature of C8H11N).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Electric Literature of C8H11N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem