Day: January 6, 2023

Hysteretic four-step spin-crossover in a 3D Hofmann-type metal-organic framework with aromatic guest was written by Zhang, Cui-Juan;Lian, Kai-Ting;Huang, Guo-Zhang;Bala, Sukhen;Ni, Zhao-Ping;Tong, Ming-Liang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Recommanded Product: 15420-02-7 This article mentions the following:

A new Hofmann-type metal-organic framework with bent pillar ligand, [Fe(dpoda){Ag(CN)₂}₂] (dpoda = 2,5-di-(pyridyl)-1,3,4-oxadiazole), was synthesized. Four-, two- and one-step spin-crossover (SCO) properties were obtained by using different sizes of aromatic guests. Most importantly, hysteretic four-step SCO behavior with the sequence of LS ↔ HS_0.25LS_0.75 ↔ HS_0.5LS_0.5 ↔ HS_0.67LS_0.33 ↔ HS is observed for the first time. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Recommanded Product: 15420-02-7).

2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 15420-02-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mixtures of Pyridine and Nicotine with Pyridinium-Based Ionic Liquids was written by Pereiro, A. B.;Rodriguez, A.;Blesic, M.;Shimizu, K.;Canongia Lopes, J. N.;Rebelo, L. P. N.. And the article was included in Journal of Chemical & Engineering Data in 2011.SDS of cas: 125652-55-3 This article mentions the following:

The melting temperatures of 1-alkyl-3-methylpyridinium chloride ionic liquids [C_nmpy]Cl (4 ≤ even n ≤ 18) were determined by a dynamic method and confirmed by differential scanning calorimetry. The latter technique was also used to measure the corresponding enthalpies of fusion. The temperatures marking the onset of decomposition of the eight ionic liquids were determined by thermogravimetry. The solid-liquid and liquid-liquid phase equilibrium of binary mixtures of pyridine or nicotine with four ionic liquids of the 1-alkyl-3-methylpyridinium chloride family ([C_nmpy]Cl with n = 4, 6, 10, 16) were investigated. The T-x phase diagrams were measured at atm. pressure using turbidimetry in the (280 to 378) K temperature range. The diagrams show that pyridine is miscible in all proportions with the four studied ionic liquids while nicotine is only partially miscible with [C₄mpy]Cl and [C₆mpy]Cl. Data were interpreted using mol. dynamics simulations. The study illustrates, once again, the unique structural and solvent properties of ionic liquids In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3SDS of cas: 125652-55-3).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.SDS of cas: 125652-55-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On the metalation of 2-isopropylpyridine was written by Pasquinet, Eric;Rocca, Patrick;Marsais, Francis;Godard, Alain;Queguiner, Guy. And the article was included in Tetrahedron in 1998.Electric Literature of C8H11N This article mentions the following:

2-Isopropylpyridine was successfully metalated and functionalized by using K diisopropylamide (KDA). Subsequent functionalization was achieved with a wide range of electrophiles and good to excellent yields were obtained. The action of other K or Na bases also was studied. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Electric Literature of C8H11N).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Electric Literature of C8H11N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Addition of novel benzylmagnesium “ate” complexes of BnR₂MgLi type to 2-(thio)pyridones and related compounds was written by Sosnicki, Jacek G.;Idzik, Tomasz;Borzyszkowska, Aleksandra;Wroblewski, Emil;Maciejewska, Gabriela;Struk, Lukasz. And the article was included in Tetrahedron in 2017.SDS of cas: 76053-45-7 This article mentions the following:

Novel benzylation reagents BnR2MgLi were obtained by mixing benzylmagnesium chloride (BnMgCl) and appropriate organolithium compounds (RLi). As BnR₂MgLi complexes are more nucleophilic than the parent Grignard compound they enabled regioselective C6-addition to electrophilic N-substituted 2-(thio)-pyridones and C4-addition to poorly reactive NH 2-(thio)pyridones in high and good yields, resp. Thus, the application of these new reagents in efficient synthesis of 6-benzyl-3,6-dihydro- and 4-benzyl-3,4-dihydropyridin-2(1H)-ones is described. The prospect of wider application of BnR₂MgLi in 1,4-addition to other electrophiles, comprising six-membered α,β-unsaturated systems is also presented. In the experiment, the researchers used many compounds, for example, 5-Phenylpyridin-2-ol (cas: 76053-45-7SDS of cas: 76053-45-7).

5-Phenylpyridin-2-ol (cas: 76053-45-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.SDS of cas: 76053-45-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Manganese-Promoted Regioselective Direct C3-Phosphinoylation of 2-Pyridones was written by Kittikool, Tanakorn;Phakdeeyothin, Kunita;Chantarojsiri, Teera;Yotphan, Sirilata. And the article was included in European Journal of Organic Chemistry in 2021.COA of Formula: C11H9NO This article mentions the following:

A highly efficient and regioselective manganese-induced radical oxidative direct C-P bond formation between 2-pyridones and secondary phosphine oxides was developed. The C3-selective phosphinoylation was conveniently achieved through a combination of substoichiometric manganese and persulfate oxidant under mild conditions. Various 3-phosphinoylated pyridone products can be obtained in moderate to high yields. Preliminary mechanistic studies suggest that the reaction is likely to involve a radical pathway induced by catalytically active Mn³⁺ species. In the experiment, the researchers used many compounds, for example, 5-Phenylpyridin-2-ol (cas: 76053-45-7COA of Formula: C11H9NO).

5-Phenylpyridin-2-ol (cas: 76053-45-7) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.COA of Formula: C11H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of some 3-substituted [1,8]Naphthyrido[3,2-c][1,8]naphthyridines. A new heterocyclic ring system was written by Ferrarini, Pier Luigi;Biagi, Giuliana;Livi, Oreste;Primofiore, Giampaolo;Carpene, Marino. And the article was included in Journal of Heterocyclic Chemistry in 1981.Formula: C7H9N3O This article mentions the following:

The title compounds (I; R = Me, Br, Cl, EtO, HS) were prepared by condensation of naphthyridinones (II) with 2-aminonicotinaldehyde. I were transformed into the fully aromatic compounds by refluxing with nitrobenzene. In the experiment, the researchers used many compounds, for example, N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3Formula: C7H9N3O).

N-(6-Aminopyridin-2-yl)acetamide (cas: 1075-62-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Formula: C7H9N3O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Diversities in the chelation of aroylhydrazones towards cobalt(II) salts: Synthesis, spectral characterization, crystal structure and some theoretical studies was written by Mangalam, Neema Ani;Kurup, M. R. Prathapachandra;Suresh, Eringathodi;Kaya, Savas;Serdaroglu, Goncagul. And the article was included in Journal of Molecular Structure in 2021.COA of Formula: C12H9NO This article mentions the following:

Five Co complexes synthesized from two aroylhydrazones were characterized by elemental analyses, TGA, molar conductivity, magnetic susceptibility measurements, IR and electronic spectra. Single crystal x-ray structure of one of the complex is also reported and it got crystallized in triclinic space group P1̅ and the crystal structure shows a distorted octahedral geometry around the metal center. Spectral data reveal that both the aroylhydrazones are tridentate and coordinate through the azomethine N, hydrazonic O, and pyridyl N. Magnetic susceptibility measurements confirm the paramagnetic nature of the Co(II) complexes and one of the complex is diamagnetic in nature. Addnl., HF/6-311G(d,p)/LANL2DZ calculations were performed to predict the possible intramol. interactions contributing to the lowering of the stabilization energy. Accordingly, π→ π^* transitions are responsible for the stabilization energy for the ligands and their Co complexes. To describe and discuss the chem. reactivity and stability of synthesized complexes, quantum chem. parameters like frontier orbital energies, hardness, softness, energy gap, electronegativity, chem. potential, electrophilicity, polarizability and dipole moment were calculated Also, the main electronic structure principles such as maximum hardness, min. polarizability, and min. electrophilicity principles were considered to evaluate the stability of the complexes. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1COA of Formula: C12H9NO).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.COA of Formula: C12H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Selective Aerobic Oxidation of C_sp³-H Bonds Catalyzed by Yeast-Derived Nitrogen, Phosphorus, and Oxygen Codoped Carbon Materials was written by Ju, Zhao-Yang;Song, Li-Na;Chong, Ming-Ben;Cheng, Dang-Guo;Hou, Yang;Zhang, Xi-Ming;Zhang, Qing-Hua;Ren, Lan-Hui. And the article was included in Journal of Organic Chemistry in 2022.HPLC of Formula: 91-02-1 This article mentions the following:

Nitrogen, phosphorus and oxygen codoped carbon catalysts were successfully synthesized using dried yeast powder as pyrolysis precursor. The yeast-derived heteroatom-doped carbon (yeast@C) catalysts exhibited outstanding performance in the oxidation of C_sp3-H bonds to ketones and esters giving excellent products yields (up to 98% yield) without organic solvents at low O₂ pressure (0.1 MPa). The catalytic oxidation protocol exhibited broad range of substrates (38 examples) with good functional group tolerance, excellent regioselectivity and synthetic utility. The yeast-derived heteroatom-doped carbon catalysts showed good reusability and stability after recycle six times without any significant loss of activity. Exptl. results and DFT calculations proved the important role of N-oxide (N⁺-O^–) on the surface of yeast@C and a reasonable carbon radical mechanism. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1HPLC of Formula: 91-02-1).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.HPLC of Formula: 91-02-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Oxidatively Induced Selective Carbon-Carbon Bond Formation From Isolated Rhodium(III) Complexes was written by Shi, Ruoyi;Tan, Jiantao;Wang, Zhifan;Wang, Yuanhua. And the article was included in Chemistry – A European Journal in 2021.Related Products of 4373-61-9 This article mentions the following:

This work focuses on oxidatively induced regioselective intramol. C-C bond formations based on the Rh^III complexes synthesized from dirhodium(II) trifluoroacetate with 2-arylpyridines. With the selection of electron-donating groups on the arene rings of 2-arylpyridines, the unusual meta-ortho C-C bond-forming was favored, which led to the formation of meta-substituted 2-arylpyridine homocoupling dimers. On the contrary, the electron-withdrawing groups have tendency to occur conventional ortho-ortho bond-forming, resulting in the formation of new Rh^III complexes possessing the intriguing Rh^III(TFA)₃ fragment. Preliminary mechanistic experiments suggest that the sequential oxidation of Rh^III occurred in the reaction. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Related Products of 4373-61-9).

2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Related Products of 4373-61-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A Facile Route to Ortho-Hydroxyanilnes through an Ir^III-Catalyzed Direct C-H Amidation of 2-Phenoxypyridines was written by Wang, Lianhui;Yang, Zi;Yang, Mengqi;Tian, Miaodou;Kuai, Changsheng;Cui, Xiuling. And the article was included in Chemistry – An Asian Journal in 2017.COA of Formula: C11H9NO This article mentions the following:

A highly efficient and regioselective Ir^III-catalyzed C-H amidation of 2-phenoxypyridines was developed by using sulfonyl azides as an amino source. The amidated products were provided in good-to-excellent yields with broad functional-group tolerance. Furthermore, the 2-pyridyl moiety in the amidated products could be readily removed, thus offering an efficient route to synthetically useful ortho-hydroxyanilnes, which are important building blocks in organic synthesis. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0COA of Formula: C11H9NO).

2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. COA of Formula: C11H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem