Related Products of 676339-81-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 676339-81-4, name is 6-(4-Carboxyphenyl)nicotinic acid, molecular formula is C13H9NO4, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
(1) Add equimolar amounts of Co (NO3) 2.6H2O (0.145g, 0.5mmol) and H2cpn (0.12g, 0.5mmol) to 12mL dmf solvent, and then stir for 20 minutes;(2) Add the material in step 1 to a 23mL polytetrafluoroethylene reactor, maintain a constant temperature of 130 C for 72 hours under autogenous pressure, and then drop to room temperature at a rate of 5 C / h;(3) The mixture in step 2 is filtered, the crystals are collected, washed with dmf solvent and dried,Purple crystals are obtained.(4) Filter the product, collect the crystals, and dry to obtain purple crystals.According to the calculation of H2cpn, the yield was 48%
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 676339-81-4, 6-(4-Carboxyphenyl)nicotinic acid.
Reference:
Patent; Zhaoqing University; Ma Deyun; Liang Fenglan; Tan Liang; Huang Yewei; Qin Jiayan; Shen Yijun; (7 pag.)CN111057113; (2020); A;,
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