COA of Formula: C7H9NOIn 2022 ,《Synthesis of Substituted Pyrano[3,4-b]Quinolines by Silver-Catalyzed Regioselective Intramolecular Cyclization of 3-Alkynylquinoline Aldehydes》 appeared in Asian Journal of Organic Chemistry. The author of the article were Vani, Damera; Chahal, Kapil; Preethi, Pagilla; Balasubramanian, Sridhar; Rajender Reddy, Kallu. The article conveys some information:
A novel approach for the synthesis of regioselective pyrano[3,4-b]quinolines from 3-alkynylquinoline aldehydes with alcs. as nucleophiles were elucidated. This protocol showed high generality of functional group and provided the pyrano-annulated products good to excellent yields. This methodol. was adopted a new synthetic strategy to develop the 3-alkynylquinolinealdehydes by using methanol as a C1 source. The results came from multiple reactions, including the reaction of 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2COA of Formula: C7H9NO)
2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.COA of Formula: C7H9NO