Adding a certain compound to certain chemical reactions, such as: 148760-75-2, tert-Butyl 1H-pyrrolo[3,2-c]pyridine-1-carboxylate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 148760-75-2, blongs to pyridine-derivatives compound. Safety of tert-Butyl 1H-pyrrolo[3,2-c]pyridine-1-carboxylate
tert-butyl pyrrolo[3,2-c]pyridine- 1 -carboxylate (P62) (100 mg, 0.46 mmol) was dissolved in ethanol (8 ml) and acetic acid (8 ml) and passed through the H-Cube (0.5 mI/mm, controlled H2, Rh/C cartridge, 60 C, 60 Bar), recycling reaction mixture for 3 % hours. The solution was concentrated under reduced pressure and the product purified by SCX (500 mg) to afford teit-butyl (3aS, 7aR)-2, 3, 3a,4, 5,6,7, 7a-octahydropyrrolo[3,2- c]pyridine- 1 -carboxylate (P64) (50 mg).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,148760-75-2, its application will become more common.
Reference:
Patent; CANCER RESEARCH TECHNOLOGY LIMITED; PUGLIESE, Angelo; FRANCIS, Stuart; MCARTHUR, Duncan; SIME, Mairi; BOWER, Justin; BELSHAW, Simone; (315 pag.)WO2019/34890; (2019); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem