Jiang, Rong’s team published research in Bioorganic & Medicinal Chemistry Letters in 17 | CAS: 197958-29-5

Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, COA of Formula: C5H6BNO2.

Jiang, Rong published the artcile3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors, COA of Formula: C5H6BNO2, the publication is Bioorganic & Medicinal Chemistry Letters (2007), 17(22), 6378-6382, database is CAplus and MEDLINE.

The structure-based design and synthesis of a novel series of c-Jun N-terminal kinase (JNK) inhibitors with selectivity against p38 is reported. The unique structure of these 3,5-disubstituted quinolines, e.g. I, was developed from the previously reported 4-(2,7-phenanthrolin-9-yl)phenol. The X-ray crystal structure of I in JNK3 reveals an unexpected binding mode for this new scaffold with protein.

Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, COA of Formula: C5H6BNO2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem