Reactions of 1-unsubstituted tautomeric 2-pyridones with benzyne was written by Kuzuya, Masayuki;Noguchi, Akihiro;Kamiya, Shoji;Okuda, Takachiyo. And the article was included in Chemical & Pharmaceutical Bulletin in 1985.Recommanded Product: 4783-68-0 This article mentions the following:
2-Pyridones I [R = H, Me; R1 = H, Me, Ph, Br; R2 = H, Me, Ph; R3 = H, Me, Br, Cl; R4 = H; R2R3 = (CH2)3, CH2CH2O] reacted with benzyne, generated in situ from 2-H2NC6H4CO2H and Me2CHCH2CH2ONO, to give benzoazabarrelenones II and large amounts of 2-phenoxypyridines. Under similar conditions I (R4 = Me) gave II only. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Recommanded Product: 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Recommanded Product: 4783-68-0