Synthesis and properties of [(thiocarbamoyl)methyl]pyridinium (isoquinolinium) ylides was written by Berseneva, V. S.;Bakulev, V. A.;Mokrushin, V. S.;Lebedev, A. T.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1989.Synthetic Route of C7H7ClN2 This article mentions the following:
Treating pyridinium or isoquinolinium ylides I (R = CN) with H2S in EtOH containing NaOEt gave ylides I (R = CSNH2). The isoquinoline derivatives were cyclized by 1-chloro-2,4-dinitrobenzene to give 32% imidazoloisoquinoline II. Addnl. obtained from I were 15 and 30% imidazolopyridine and isoquinolines III, resp. In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3Synthetic Route of C7H7ClN2).
1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Synthetic Route of C7H7ClN2