N-O Bond as External Oxidant in Group 9 Cp*M(III)-Catalyzed Oxidative C-H Coupling Reactions was written by Liu, Xu-Ge;Gao, Hui;Zhang, Shang-Shi;Li, Qingjiang;Wang, Honggen. And the article was included in ACS Catalysis in 2017.Application of 4373-61-9 This article mentions the following:
O-Acylhydroxylamines and peresters were tried as external oxidants in rhodium-, iridium-, and cobalt-catalyzed oxidative coupling reactions; O-acylhydroxylamines such as RCOONEt2 (R = Me, t-Bu) and 2,6-(MeO)2C6H3COONR12 (R1 = Et, i-Pr) were found to be effective oxidants for oxidative coupling reactions of benzoic acids and benzophenone imines with alkynes and for oxidative Heck reactions of arylpyridines and 2-phenylpyrimidine with styrenes to give isocoumarines, isoquinolines, and pyridinyl- and pyrimidinylstilbenes. Using the Cp*Rh(III)-catalyzed isocoumarin synthesis as a model reaction, exptl. and theor. mechanistic studies were conducted to understand the mechanism of the oxidative coupling reactions using O-acylhydroxylamines as oxidants. A Rh(III)-Rh(I)-Rh(III) pathway is more likely involved in the oxidative coupling reactions than a Rh(III)-Rh(V)-Rh(III) pathway; both C-H activation and oxidation of the Cp*Rh(I) species were involved in the turnover-limiting step. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Application of 4373-61-9).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application of 4373-61-9