Condensed as-triazines. V. Pyrido[4,3-e]-as-triazines was written by Benko, Pal;Berenyi, Edit;Messmer, Andras;Hajos, Gyorgy;Pallos, Laszlo. And the article was included in Acta Chimica Academiae Scientiarum Hungaricae in 1976.Application In Synthesis of 3,4-Dichloro-5-nitropyridine This article mentions the following:
Pyridotriazine oxides I (R = H, Cl) were obtained in 84.5 and 59.7% yields by base-catalyzed cyclocondensation of guanidine with a 4-methoxy-3-nitropyridine. Treatment of I (R = H) with base gave 41.7% of the rearranged triazoleamide II. Addnl. obtained were 35% and 24% III (R = PhCH2NH, morpholino). In the experiment, the researchers used many compounds, for example, 3,4-Dichloro-5-nitropyridine (cas: 56809-84-8Application In Synthesis of 3,4-Dichloro-5-nitropyridine).
3,4-Dichloro-5-nitropyridine (cas: 56809-84-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application In Synthesis of 3,4-Dichloro-5-nitropyridine