Ruthenium(II)-Catalyzed C-H Acyloxylation of Phenols with Removable Auxiliary was written by Raghuvanshi, Keshav;Rauch, Karsten;Ackermann, Lutz. And the article was included in Chemistry – A European Journal in 2015.Product Details of 4783-68-0 This article mentions the following:
Intermol. C-H acyloxylations of phenols with removable directing groups were accomplished with a versatile ruthenium catalyst. Specifically, a cationic ruthenium(II) complex, formed in-situ, enabled the chemoselective C-H oxygenations of a broad range of substrates. The catalyst proved tolerant of synthetically valuable functional groups, and the substrate scope included both (hetero)aromatic and, the more challenging, aliphatic carboxylic acids. The proposed reaction mechanism involved a reversible C-H ruthenation and an oxidatively induced C-O-bond-forming reductive elimination. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Product Details of 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Product Details of 4783-68-0