Synthesis and characterization of copper(I) and silver(I) complexes with heterocyclic bidentate ligands (N, X), X = S, Se was written by Sousa-Pedrares, Antonio;Duran-Carril, Maria Luz;Romero, Jaime;Arturo Garcia-Vazquez, J.;Sousa, Antonio. And the article was included in Inorganica Chimica Acta in 2010.Application In Synthesis of 2-Bromo-3-(trifluoromethyl)pyridine This article mentions the following:
The synthesis and structural characterization of series of copper and silver homoleptic complexes [M(R-pyX)] (py = 2-pyridine, M = Cu, Ag, X = S, Se; R = H, 3-CF3, 5-CF3 (not all combinations)), is described. The copper compounds, as well as [Ag(pySe)] and [Ag(3-CF3-pySe)], were synthesized by electrochem. oxidation of anodic metal in a cell containing an acetonitrile solution of the corresponding proligand. The other homoleptic silver complexes were obtained by direct reaction between AgNO3 and the salt of the corresponding ligand in methanol. The reaction of the metal thiolate compounds with bis(diphenylphosphino)ethane (dppe) in acetone gave heteroleptic compounds [M2(R-pyX)2(dppe)3]. The compounds obtained were characterized by microanal., IR spectroscopy and mass spectrometry and, in cases where the complexes were sufficiently soluble, by 1H NMR spectroscopy. The proligands (3-CF3pySe)2 (1), (5-CF3-pySe)2 (2) and (5-CF3-pySe-DMF) (3) and [Cu(3-CF3-pyS)] (4), [Ag(3-CF3-pyS)] (5) and [Cu2(5-CF3-pyS)2(dppe)3] (6) were obtained as crystalline products and were studied by x-ray diffraction methods. In the experiment, the researchers used many compounds, for example, 2-Bromo-3-(trifluoromethyl)pyridine (cas: 175205-82-0Application In Synthesis of 2-Bromo-3-(trifluoromethyl)pyridine).
2-Bromo-3-(trifluoromethyl)pyridine (cas: 175205-82-0) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Application In Synthesis of 2-Bromo-3-(trifluoromethyl)pyridine