Halogenation of N-oxides of pyridine acetylamino derivatives was written by Talik, Tadeusz;Talik, Zofia. And the article was included in Prace Naukowe Akademii Ekonomicznej imienia Oskara Langego we Wroclawiu in 1983.HPLC of Formula: 31430-47-4 This article mentions the following:
2-Acetamidopyridine N-oxide with HCl or HBr and H2O2 gave the 5-chloro amine oxide, the 3,5-Cl2 analog, and the 3,5-Br2 analog; the 3-acetamido analog gave 2,4,6-trihalo amine oxides, and the 4-acetamido analog, as well as 2-acetamido-4- and -6-picoline N-oxides, gave 3,5-dihalo amine oxides (e.g., I and II), while 2-acetamido-3-picoline N-oxide gave 5-halo amine oxides; 2-acetamido-5-picoline underwent only the hydrolysis. In the experiment, the researchers used many compounds, for example, 3,5-Dichloro-4-methylpyridin-2-amine (cas: 31430-47-4HPLC of Formula: 31430-47-4).
3,5-Dichloro-4-methylpyridin-2-amine (cas: 31430-47-4) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.HPLC of Formula: 31430-47-4