Copper(II)-Promoted Mono-Selective ortho C-H Chlorination of Arenes by Using Trimethyl(trichloromethyl)silane was written by Zhu, Zhaobin;Xu, Changming;Wang, Yongchang;Zhao, Li. And the article was included in Synlett in 2018.Name: 2-(m-Tolyl)pyridine This article mentions the following:
The first example of a Cu-promoted ortho-chlorination of aryl C-H bonds by using TMSCCl3as chlorinating agent is reported. This reaction features a high selectivity toward monochlorination over dichlorination, compatibility with a variety of functional groups, and gram-scale synthesis. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Name: 2-(m-Tolyl)pyridine).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Name: 2-(m-Tolyl)pyridine