Aerobic Oxidation of PdII to PdIV by Active Radical Reactants: Direct C-H Nitration and Acylation of Arenes via Oxygenation Process with Molecular Oxygen was written by Liang, Yu-Feng;Li, Xinyao;Wang, Xiaoyang;Yan, Yuepeng;Feng, Peng;Jiao, Ning. And the article was included in ACS Catalysis in 2015.Reference of 4783-68-0 This article mentions the following:
In the presence of Pd(OAc)2, fused and unfused 2-arylpyridines and aryl-substituted nitrogen heterocycles, O-Me oximes of aryl ketones, and diaryl diazenes underwent regioselective aerobic nitration with tert-Bu nitrite and regioselective benzoylation with substituted toluenes in the presence of N-hydroxyphthalimide to yield nitroarenes and aryl ketones. The reactions are proposed to operate via a Pd(II)/Pd(IV) catalytic cycle. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Reference of 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 4783-68-0