Sulfonyl Fluoride Synthesis through Electrochemical Oxidative Coupling of Thiols and Potassium Fluoride was written by Laudadio, Gabriele;Bartolomeu, Aloisio de A.;Verwijlen, Lucas M. H. M.;Cao, Yiran;de Oliveira, Kleber T.;Noel, Timothy. And the article was included in Journal of the American Chemical Society in 2019.Category: pyridine-derivatives This article mentions the following:
Sulfonyl fluorides are valuable synthetic motifs for a variety of applications, among which sulfur(VI) fluoride exchange-based “click chem.” is currently the most prominent. Consequently, the development of novel and efficient synthetic methods to access these functional groups is of great interest. Herein, the authors report a mild and environmentally benign electrochem. approach to prepare sulfonyl fluorides using thiols or disulfides, as widely available starting materials, in combination with KF, as an inexpensive, abundant and safe fluoride source. No addnl. oxidants nor addnl. catalysts are required and, due to mild reaction conditions, the reaction displays a broad substrate scope, including a variety of alkyl, benzyl, aryl and heteroaryl thiols or disulfides. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Category: pyridine-derivatives).
Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Category: pyridine-derivatives