Extended knowledge of 2-Amino-5-nitropyridine

According to the analysis of related databases, 4214-76-0, the application of this compound in the production field has become more and more popular.

Related Products of 4214-76-0, Adding some certain compound to certain chemical reactions, such as: 4214-76-0, name is 2-Amino-5-nitropyridine,molecular formula is C5H5N3O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 4214-76-0.

General procedure: Under an Ar atmosphere, N-chlorosuccinimide (0.53 g,3.95 mmol) was added to a solution of compound 1 (0.50 g,3.59 mmol) in anhydrous toluene (7.18 mL). The resulting reactionmixture was stirred at 80 C for 1 h. The reaction mixture wascooled to room temperature and 15 mL of H2O was added to thismixture. It was then extracted with EtOAc, washed with sat.NaHCO3 solution, brine, concentrated under vacuum, and purifiedby column chromatography (KANTO 60 N, Hex/EtOAc = 80/20 to60/40) to give a yellow solid 2a (0.40 g, 2.30 mmol, 64percent).

According to the analysis of related databases, 4214-76-0, the application of this compound in the production field has become more and more popular.

Reference:
Article; Wang, Lei; Taniguchi, Yosuke; Okamura, Hidenori; Sasaki, Shigeki; Bioorganic and Medicinal Chemistry; vol. 25; 14; (2017); p. 3853 – 3860;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem