Adding a certain compound to certain chemical reactions, such as: 918503-72-7, 1-(6-Chloropyridin-3-yl)butan-1-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C9H10ClNO, blongs to pyridine-derivatives compound. Computed Properties of C9H10ClNO
1-(6-aminopyridin-3-yl)butan-1-one (b) (0215) 3.5 g of the above ketone ( a) was placed in a microwave reactor, and 20 mL of NH3 (aq. conc.) was added and the reactor was sealed and heated at 140 C. for 2 h. The reaction mixture was poured over water (50 mL), filtered, and rinsed with EtOH/water (1:1) to give 1-(6-aminopyridin-3-yl)butan-1-one (b, 3.5 g) as a white crude product.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,918503-72-7, 1-(6-Chloropyridin-3-yl)butan-1-one, and friends who are interested can also refer to it.
Reference:
Patent; Synta Pharmaceuticals Corp.; Chen, Shoujun; Bohnert, Gary; Jiang, Jun; Xia, Zhiqiang; (151 pag.)US9604978; (2017); B2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem