9 Sep 2021 News Extracurricular laboratory: Synthetic route of 1239363-36-0

The synthetic route of 1239363-36-0 has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 1239363-36-0, tert-Butyl 2′,6′-dichloro-5,6-dihydro-[4,4′-bipyridine]-1(2H)-carboxylate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: tert-Butyl 2′,6′-dichloro-5,6-dihydro-[4,4′-bipyridine]-1(2H)-carboxylate, blongs to pyridine-derivatives compound. Recommanded Product: tert-Butyl 2′,6′-dichloro-5,6-dihydro-[4,4′-bipyridine]-1(2H)-carboxylate

18-1 (1.62 g, 4.9 mmol) was treated with PtO2 (0.16 g) under a H2 atmosphere for 1 h. The catalyst was removed by filtration, and 18-2 (1.46 g, 90%) was used without further purification. LC/MS: m/z 331.10 [M+H]+.

The synthetic route of 1239363-36-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Alios BioPharma, Inc.; Wang, Guangyi; Beigelman, Leonid; Truong, Anh; Stein, Karin Ann; (234 pag.)US2016/244460; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem