Electric Literature of 173528-92-2 ,Some common heterocyclic compound, 173528-92-2, molecular formula is C20H18N2O3S, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
EXAMPLE 8 (E)-4-[2-[2-[[(p-Hydroxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine In DMF was dissolved 2.00 g of the (E)-4-[2-[2-[[(p-methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine obtained in Example 3, followed by addition of 1.91 g of sodium methanethiolate, and the mixture was stirred at 100 C. overnight and then after-treated. The resulting crystals were recrystallized from methanol to provide 0.19 g of the title compound (white powders). m.p. 293-296 C. (decomp.) Elemental analysis for C19 H16 N2 O3 S
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 173528-92-2, HMN-154, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Nippon Shinyaku Company, Limited; US5972976; (1999); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem