A flexible, convergent route to azaoxindoles, azaindolines, azaindoles, and tetrahydroazaquinolones was written by Bacque, Eric;El Qacemi, Myriem;Zard, Samir Z.. And the article was included in Heterocycles in 2012.Reference of 209798-48-1 This article mentions the following:
A variety of azaoxindoles, azaindolines, azaindoles, and tetrahydroazaquinolones were readily prepared by cyclization of xanthate-derived radicals onto pyridine rings. The xanthate precursors may themselves be produced by intermol. radical addition-transfer to allylamino- or butenoylamide side-chains. In the experiment, the researchers used many compounds, for example, (2-Chloro-pyridin-3-yl)-carbamic acid tert-butyl ester (cas: 209798-48-1Reference of 209798-48-1).
(2-Chloro-pyridin-3-yl)-carbamic acid tert-butyl ester (cas: 209798-48-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Reference of 209798-48-1