Related Products of 4684-94-0 ,Some common heterocyclic compound, 4684-94-0, molecular formula is C6H4ClNO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: An oven dried resealable screw cap standard reaction tube containinga magnetic stir bar was charged with potassium persulfate(1.75 mmol, 472.5 mg), bismuth nitrate (1.0 mmol, 486 mg). Thenaryl carboxylic (0.5 mmol) was introduced in this mixture followedby acetonitrile (3 mL) was added in it. The tube was placed in apreheated oil bath at 130 C and the reaction mixture was stirredvigorously for 24 h in air atmosphere. The reaction mixture wascooled to room temperature, diluted with 2 mL ethyl acetate andfiltered through celite, eluting with additional 10 mL of ethyl acetate.The filtrate was concentrated and the resulting residue waspurified by column chromatography.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,4684-94-0, its application will become more common.
Reference:
Article; Agasti, Soumitra; Maiti, Siddhartha; Maity, Soham; Anniyappan; Talawar; Maiti, Debabrata; Polyhedron; vol. 172; (2019); p. 120 – 124;,
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