The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1009735-24-3, name is Methyl 6-bromo-2-methoxynicotinate. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: Methyl 6-bromo-2-methoxynicotinate
Step 3: 6-bromo-2-methoxy-nicotinamjde; beta-bromo^-methoxy-nicotinic acid methyl ester (0.45g, 183mmol) and ammonium hydroxide (5 mL) were combined in a sealed tube and heated to 700C for 3 h. The reaction was cooled to room temperature, filtered and rinsed with water to obtain the title compound as a white solid (0.278 g, 66%). 1 H NMR (500 MHz, DMSO-d6) delta ppm 3.96 (3 H, s), 7.35 (1 H, d, J=7.8 Hz), 7.68 (1 H, br. s.), 7.76 (1 H, br. s.), 8.04 (1 H, d, J=7.8 Hz).
With the rapid development of chemical substances, we look forward to future research findings about 1009735-24-3.
Reference:
Patent; PFIZER INC.; ARHANCET, Graciela Barbieri; CASIMIRO-GARCIA, Agustin; CHEN, Xiangyang; HEPWORTH, David; MEYERS, Marvin Jay; PIOTROWSKI, David Walter; RAHEJA, Raj Kumar; WO2010/116282; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem