Category: 102074-19-1

Introduction of a new synthetic route about 102074-19-1

The chemical industry reduces the impact on the environment during synthesis 102074-19-1, I believe this compound will play a more active role in future production and life.

Reference of 102074-19-1, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.102074-19-1, name is (5-Methylpyridin-3-yl)methanol, molecular formula is C7H9NO, molecular weight is 123.15, as common compound, the synthetic route is as follows.

Step 2.; Alcohol (10 mmol) were refluxed in 10ml HBr (40% aq) for more than 5 hours, and monitored through TLC or LC-MS. After completed, mixture were heated in order to evaporator solvents (water and excess HBr) until the mixture became sticky. Cool the mixture, add acetone to the mixture, precipitated solid and filtered followed by drying. Yield was high to80%.

The chemical industry reduces the impact on the environment during synthesis 102074-19-1, I believe this compound will play a more active role in future production and life.

Reference:
Patent; ACEA BIOSCIENCES INC.; MAO, Long; ZHAO, Li; LIU, Jia; WANG, Xiaobo; XU, Xiao; WO2012/97196; (2012); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 102074-19-1

At the same time, in my other blogs, there are other synthetic methods of this type of compound,102074-19-1, (5-Methylpyridin-3-yl)methanol, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 102074-19-1, (5-Methylpyridin-3-yl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C7H9NO, blongs to pyridine-derivatives compound. Computed Properties of C7H9NO

Step 2. 5-methyl-3-pyridinecarboxaldehyde. A mixture of 5-methyl-3-pyridinemethanol (106 mg, 0.86 mmol) and activated MnO2 (376 mg) in methylenechloride (10 mL) was stirred at room temperature overnight. The black solid of MnO2 was removed by filtration. The filtrate was concentrated in vacuo to yield the title compound as an oil (100 mg, 85%). 1H NMR (CDCl3): 10.10 (s, 1H), 8.89 (s, 1H), 8.68 (s, 1H), 7.98 (s, 1H), 2.45 (s, 3H)

At the same time, in my other blogs, there are other synthetic methods of this type of compound,102074-19-1, (5-Methylpyridin-3-yl)methanol, and friends who are interested can also refer to it.

Reference:
Patent; Cytovia, Inc.; EP1230232; (2004); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem