Category: 1174626-28-8

Tan, Jing published the artcileMetal- and base-free synthesis of imidazo[1,2-a]pyridines through elemental sulfur-initiated oxidative annulation of 2-aminopyridines and aldehydes, Category: pyridine-derivatives, the publication is Organic & Biomolecular Chemistry (2018), 16(23), 4227-4230, database is CAplus and MEDLINE.

Arylacetaldehydes and aliphatic aldehydes underwent oxidative cyclocondensation reactions with aminopyridines mediated by S₈ in cyclohexane/DMSO to yield imidazopyridines without added metal or base.

Organic & Biomolecular Chemistry published new progress about 1174626-28-8. 1174626-28-8 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine,Benzene,Ether, name is 2-Amino-6-benzyloxypyridine, and the molecular formula is C20H17FO4S, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Mu, Bing published the artcilePd-Catalyzed Tandem Cyclization via C-H Arylation and Acylation for the Construction of Polycyclic Scaffolds, Computed Properties of 1174626-28-8, the publication is Organic Letters (2016), 18(20), 5260-5263, database is CAplus and MEDLINE.

The first Pd-catalyzed tandem cyclization of imidazo[1,2-a]pyridines with 2-chlorobenzaldehydes through C-H arylation and acylation is presented for the efficient synthesis of novel 6H-benzo[b]imidazo[5,1,2-de]quinolizin-6-ones. The direct acylation reaction proceeded smoothly without the aid of directing groups and in the presence of air as a clean and free terminal oxidant.

Organic Letters published new progress about 1174626-28-8. 1174626-28-8 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine,Benzene,Ether, name is 2-Amino-6-benzyloxypyridine, and the molecular formula is C12H12N2O, Computed Properties of 1174626-28-8.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Saha, Debasmita published the artcileIntramolecular cyclization of imidazo[1,2-a]pyridines via a silver mediated/palladium catalyzed C-H activation strategy, HPLC of Formula: 1174626-28-8, the publication is Organic Chemistry Frontiers (2019), 6(13), 2234-2239, database is CAplus.

A C-H activation reaction was developed using imidazo[1,2-a]pyridine adducts via an AgOAc-mediated, Pd catalyzed intramol. cyclization for the preparation of tetrazolylpyridoimidazo[4,5-c]quinoline derivatives I (R¹ = H, 9-Me, 9-Br, etc.; R² = t-Bu, Bn, cyclohexyl, etc.). The reaction was optimized and extensively explored using the Ugi/azide MCR as a tool to rapidly broaden substrate scope. Title compounds were screened against a cancer cell panel, and I (R¹ = H; R² = 1-phenylethyl) exhibited selective, antiproliferative activity against the MCF-7 (breast cancer) cell line. This C-H activation methodol. can be utilized to rapidly reach new chem.-space for drug discovery.

Organic Chemistry Frontiers published new progress about 1174626-28-8. 1174626-28-8 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine,Benzene,Ether, name is 2-Amino-6-benzyloxypyridine, and the molecular formula is C12H12N2O, HPLC of Formula: 1174626-28-8.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem