Category: 13602-82-9

Reference of 13602-82-9, Adding some certain compound to certain chemical reactions, such as: 13602-82-9, name is N-(2-Chloropyridin-4-yl)acetamide,molecular formula is C7H7ClN2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13602-82-9.

A mixture of 10 g (59 mmol) N~(2-chloropyridin-4-yl)acetamide (commercially available), 9.8 g (17.6 mmol) pulverized KOH and 4.1 ml (6.4 mmol) methyl iodide in 60 ml acetone was stirred at room temperature for 2 h. After evaporation of all volatiles the residue was taken up in water and extracted with ethyl acetate. The combined organic layers were dried with MgSQ4 and evaporated to yield 7.1 g (66%) of the title compound as off-white solid. MS: (m/e): 345.2 (MH+).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 13602-82-9, N-(2-Chloropyridin-4-yl)acetamide, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; F.HOFFMANN-LA ROCHE AG; WO2006/63718; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 13602-82-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 13602-82-9, name is N-(2-Chloropyridin-4-yl)acetamide. This compound has unique chemical properties. The synthetic route is as follows.

A mixture of 4.6 g (27 mmol) N-(2-chloropyridin-4-yl)acetamide (commercially available) and 5.2 g (41 mmol) l-(2-propyl-)-pirhoerazine in 2 ml DMF was heated to 150 0C for 4 h. Purification of the crude mixture with flash column chromatography on silica eluting with a gradient formed from DCM (1% NEt3) and methanol yielded after evaporation of the product fractions 3.38 g (47%) of the title compound as white solid. MS: (m/e): 263.4 (MH+).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 13602-82-9, N-(2-Chloropyridin-4-yl)acetamide.

Reference:
Patent; F.HOFFMANN-LA ROCHE AG; WO2006/63718; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 13602-82-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 13602-82-9, name is N-(2-Chloropyridin-4-yl)acetamide. This compound has unique chemical properties. The synthetic route is as follows.

A mixture of 4.6 g (27 mmol) N-(2-chloropyridin-4-yl)acetamide (commercially available) and 5.2 g (41 mmol) l-(2-propyl-)-pirhoerazine in 2 ml DMF was heated to 150 0C for 4 h. Purification of the crude mixture with flash column chromatography on silica eluting with a gradient formed from DCM (1% NEt3) and methanol yielded after evaporation of the product fractions 3.38 g (47%) of the title compound as white solid. MS: (m/e): 263.4 (MH+).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 13602-82-9, N-(2-Chloropyridin-4-yl)acetamide.

Reference:
Patent; F.HOFFMANN-LA ROCHE AG; WO2006/63718; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem