Category: 145934-89-0

Application of 145934-89-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 145934-89-0, name is 2-Chloro-5-hydrazinylpyridine. This compound has unique chemical properties. The synthetic route is as follows.

Step B: 1 -(6-fluoropyridin-3-yl)-3-pyridin-3-yl-5-ftrifiuoromethyl)-4,5-dihydro-l H-pgammarazol-5-olA solution of 2-chloro-5-hydrazinopyridine (136 mg, 0.95 mmol) and acetic acid (0.29 mL, 5,00 mmol) in ethanol (2 mL) is added to a stirred solution of (lZ)-45454-trifluoro-l-pyridin-3-ylbut-l- ene-l,3,3-triol (160 mg, 0,68 mmol) in ethanol (2 mL) in a pressure tube. The reaction mixture is heated at 90 0C (oil bath temp) overnight, cooled and concentrated. The residue was purified by silica gel chromatography (2% to 10% MeOH in CH2Cl2). LRMS: m/z found: 343.5 (M+l).

According to the analysis of related databases, 145934-89-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; MERCK & CO., INC.; WO2009/151800; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 145934-89-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 145934-89-0, name is 2-Chloro-5-hydrazinylpyridine. This compound has unique chemical properties. The synthetic route is as follows.

Step B: 1 -(6-fluoropyridin-3-yl)-3-pyridin-3-yl-5-ftrifiuoromethyl)-4,5-dihydro-l H-pgammarazol-5-olA solution of 2-chloro-5-hydrazinopyridine (136 mg, 0.95 mmol) and acetic acid (0.29 mL, 5,00 mmol) in ethanol (2 mL) is added to a stirred solution of (lZ)-45454-trifluoro-l-pyridin-3-ylbut-l- ene-l,3,3-triol (160 mg, 0,68 mmol) in ethanol (2 mL) in a pressure tube. The reaction mixture is heated at 90 0C (oil bath temp) overnight, cooled and concentrated. The residue was purified by silica gel chromatography (2% to 10% MeOH in CH2Cl2). LRMS: m/z found: 343.5 (M+l).

According to the analysis of related databases, 145934-89-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; MERCK & CO., INC.; WO2009/151800; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 145934-89-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 145934-89-0, name is 2-Chloro-5-hydrazinylpyridine. This compound has unique chemical properties. The synthetic route is as follows.

Step B: 1 -(6-fluoropyridin-3-yl)-3-pyridin-3-yl-5-ftrifiuoromethyl)-4,5-dihydro-l H-pgammarazol-5-olA solution of 2-chloro-5-hydrazinopyridine (136 mg, 0.95 mmol) and acetic acid (0.29 mL, 5,00 mmol) in ethanol (2 mL) is added to a stirred solution of (lZ)-45454-trifluoro-l-pyridin-3-ylbut-l- ene-l,3,3-triol (160 mg, 0,68 mmol) in ethanol (2 mL) in a pressure tube. The reaction mixture is heated at 90 0C (oil bath temp) overnight, cooled and concentrated. The residue was purified by silica gel chromatography (2% to 10% MeOH in CH2Cl2). LRMS: m/z found: 343.5 (M+l).

According to the analysis of related databases, 145934-89-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; MERCK & CO., INC.; WO2009/151800; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem